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Long-term debt (Details) - USD ($)
$ in Millions
 3 Months Ended
Apr. 01, 2024
Mar. 31, 2024
Mar. 31, 2023
Jan. 05, 2027
Dec. 01, 2025
Dec. 31, 2023
Long-term Debt            
Investment, Variable Interest Rate, Type [Extensible Enumeration]   Prime Rate        
2023 Amended Facility            
Long-term Debt            
Outstanding debt   $ 100.0        
Interest rate (as a percent)   7.95%        
Amortized cost net of discount and debt issuance costs   $ 103.3       $ 102.9
Foreign currency loss   2.3        
Foreign currency gain     $ 0.7      
Interest expense recorded   $ 3.7 $ 3.6      
2023 Amended Facility | Forecast            
Long-term Debt            
Back-end fees       $ 1.3 $ 4.9  
2023 Amended Facility | Prime Rate            
Long-term Debt            
Variable interest rate basis   7.95%        
Discount rate (as a percent)   3.25%        
Venture debt loan facility | 2023 Amended Facility            
Long-term Debt            
Minimum cash and cash equivalents in U.S. bank accounts   65.00% 100.00%      
Assets pledged to secure facilities by directly or indirectly   $ 770.1        
Assets not being pledged to secure facilities by directly or indirectly   6.8        
Venture debt loan facility | 2023 Amended Facility | uniQure France            
Long-term Debt            
Assets not being pledged to secure facilities by directly or indirectly   $ 87.7        
Subsequent events. | Venture debt loan facility | 2023 Amended Facility            
Long-term Debt            
Minimum cash and cash equivalents in U.S. bank accounts 30.00%