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Royalty financing agreement (Details)
$ in Thousands
 3 Months Ended
May 12, 2023
USD ($)
Mar. 31, 2024
USD ($)
Mar. 31, 2023
USD ($)
Dec. 31, 2038
Jun. 30, 2032
USD ($)
Collaboration arrangements          
Royalty financing agreement interest expense   $ 12,362      
Interest Expense   16,097 $ 3,562    
CLS          
Collaboration arrangements          
Maximum rights to all other royalties, as well as contractual milestones retained   1,300,000      
Royalty financing agreement          
Collaboration arrangements          
Upfront payment received $ 375,000        
Additional milestone payment $ 25,000        
Ratio of upfront payment 1.85        
Upfront payment payable to purchaser $ 693,800 693,800      
Royalty financing agreement interest expense   12,362      
Net proceeds from the Royalty Financing Agreement   370,100      
Payment of debt issuance costs   4,900      
Interest Expense   $ 12,400 $ 0    
Royalty financing agreement | Minimum          
Collaboration arrangements          
Effective interest rate (as a percent)   12.00%      
Interest Expense   $ 12,100      
Royalty financing agreement | Maximum          
Collaboration arrangements          
Effective interest rate (as a percent)   13.50%      
Interest Expense   $ 13,700      
Royalty financing agreement | First Hard Cap Date          
Collaboration arrangements          
Ratio of upfront payment         1.85
Upfront payment payable to purchaser         $ 25,000
Royalty financing agreement interest expense   323,700      
Royalty financing agreement | If paid through December 31, 2038          
Collaboration arrangements          
Ratio of upfront payment       2.25  
Royalty financing agreement | If 2024 net sales do not exceed a pre-specified threshold          
Collaboration arrangements          
Upfront payment payable to purchaser   $ 25,000