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Share-based compensation - Option activity and weighted-average assumptions (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Dec. 31, 2023
Weighted average exercise price      
Total weighted average grant date fair value of options issued during the period (in $ millions) $ 3,000    
Proceeds from Issuance of Shares under Incentive and Share-based Compensation Plans, Including Stock Options   $ 131  
The 2014 Plan [Member]      
Weighted average exercise price      
Vesting period (in years) 4 years    
The 2014 Plan [Member] | Share options      
Options      
Outstanding at beginning of the period (in shares) 4,974,030    
Granted (in shares) 930,900    
Forfeited (in shares) (71,437)    
Expired (in shares) (11,584)    
Outstanding at end of the period (in shares) 5,821,909   4,974,030
Thereof, fully vested and exercisable at end of period (in shares) 3,054,242    
Thereof, outstanding and expected to vest after at end of period (in shares) 2,767,667   2,098,557
Weighted average exercise price      
Outstanding at beginning of the period (in dollars per share) $ 23.25    
Granted (in dollars per share) 5.59    
Forfeited (in dollars per share) 21.26    
Expired (in dollars per share) 37.61    
Outstanding at end of period (in dollars per share) 20.42   $ 23.25
Thereof, fully vested and exercisable at end of period (in dollars per share) 25.70    
Outstanding and expected to vest after at end of the period (in dollars per share) $ 14.60   $ 23.38
Weighted-average assumptions used to estimate fair value of share options granted during year      
Expected volatility (as a percent) 70.00% 70.00%  
Expected terms (in years) 10 years 10 years  
Risk free interest rate (as a percent) 4.32% 4.10%  
Expected dividend (as a percent) 0.00% 0.00%  
The 2014 Plan [Member] | Non-executive directors      
Weighted average exercise price      
Vesting period (in years) 1 year    
The 2014 Plan [Member] | One year from grant date      
Weighted average exercise price      
Vesting percentage per year 25.00%    
Vesting period (in years) 1 year