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UNAUDITED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Total revenues $ 8,485 $ 5,325
Operating expenses:    
Cost of license revenues (150)  
Cost of contract manufacturing revenues (9,076) (2,435)
Research and development expenses (40,692) (60,809)
Selling, general and administrative expenses (13,937) (17,848)
Total operating expenses (63,855) (81,092)
Other income 1,376 1,811
Other expense (234) (216)
Loss from operations (54,228) (74,172)
Interest income 6,508 1,669
Interest expense (16,097) (3,562)
Foreign currency losses, net (1,145) (2,369)
Loss before income tax (expense) / benefit (64,962) (78,434)
Income tax (expense) / benefit (656) 1,207
Net loss (65,618) (77,227)
Other comprehensive (loss) / income:    
Foreign currency translation (loss) / gains, net (2,524) 5,797
Defined benefit pension gain, net of taxes 35  
Total comprehensive loss $ (68,107) $ (71,430)
Earnings per ordinary share - basic    
Basic net (loss) / income per ordinary share $ (1.36) $ (1.63)
Earnings per ordinary share - diluted    
Diluted net (loss) / income per ordinary share $ (1.36) $ (1.63)
Weighted average shares - basic 48,384,510 47,436,335
Weighted average shares - diluted 48,384,510 47,436,335
License revenues    
Total revenues $ 1,202 $ 0
Contract manufacturing revenues    
Total revenues 3,990 4,937
Collaboration revenues    
Total revenues $ 3,293 $ 388