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v3.25.2

UNAUDITED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2025 | Jun. 30, 2024
Cash flows from operating activities |  |
Net loss | $ (81,356) | $ (121,917)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 8,157 | 5,299
Amortization of discount on investment securities | (4,163) | (6,672)
Share-based compensation expense | 9,494 | 14,071
Royalty financing agreement interest expense, net of interest paid | 20,626 | 22,172
Deferred tax expense | 921 | 1,604
Changes in fair value of contingent consideration | 3,470 | (1,621)
Unrealized foreign exchange (gains) / losses, net | (25,163) | 2,940
Provision for inventory write-downs |  | 5,839
Other items, net | (3,651) | 1,681
Changes in operating assets and liabilities: |  |
Accounts receivable, prepaid expenses, and other current assets and receivables | (6,761) | (7,227)
Inventories |  | (2,606)
Accounts payable | (2,297) | (1,619)
Accrued expenses, other liabilities, and operating leases | (3,272) | (5,230)
Net cash used in operating activities | (83,995) | (93,286)
Cash flows from investing activities |  |
Proceeds on maturity of debt securities | 213,763 | 297,806
Investment in debt securities | (120,205) | (152,936)
Purchases of property, plant, and equipment | (386) | (2,948)
Net cash generated from investing activities | 93,172 | 141,922
Cash flows from financing activities |  |
Proceeds from public offering of shares in connection with follow on, net of issuance costs | 80,511 |
Proceeds from issuance of ordinary shares related to employee stock option and purchase plans | 203 | 50
Net cash generated from financing activities | 80,714 | 50
Currency effect on cash, cash equivalents and restricted cash | 5,052 | (2,191)
Net increase in cash, cash equivalents and restricted cash | 94,943 | 46,495
Cash, cash equivalents and restricted cash at beginning of period | 160,329 | 244,544
Cash, cash equivalents and restricted cash at the end of period | 255,272 | 291,039
Cash and cash equivalents | 253,778 | 287,877
Restricted cash related to leasehold and other deposits | 1,494 | 3,162
Total cash, cash equivalents and restricted cash | 255,272 | 291,039
Supplemental cash flow disclosures: |  |
Cash paid for interest | (9,652) | (9,261)
Non-cash decrease in accounts payables and accrued expenses and other current liabilities related to purchases of property, plant, and equipment | $ (95) | $ (458)

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