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v3.25.2

Segment Reporting - Schedule of segment reporting (Details) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 USD ($) | Jun. 30, 2024 USD ($) | Jun. 30, 2025 USD ($) segment | Jun. 30, 2024 USD ($)
Segment reporting |  |  |  |
Number of operating segments | segment |  |  | 1 |
Revenue | $ 5,262 | $ 11,126 | $ 6,829 | $ 19,611
Loss from operations | (43,865) | (44,010) | (83,196) | (98,238)
Depreciation and amortization expense |  |  | (8,157) | (5,299)
Fair value loss - contingent consideration |  |  | (3,470) | 1,621
Foreign currency gains / (losses), net | 18,638 | (989) | 25,810 | (2,134)
Interest income | 3,524 | 5,805 | 7,651 | 12,313
Interest expense - Royalty Financing Agreement |  |  | (20,626) | (22,172)
Loss before income tax expense | (37,294) | (55,351) | (80,435) | (120,313)
Operating Segment | Single Reportable Segment |  |  |  |
Segment reporting |  |  |  |
Revenue | 5,262 | 11,126 | 6,829 | 19,611
Employee related expenses | (14,525) | (22,665) | (28,741) | (47,048)
Laboratory and development expenses | (15,593) | (9,404) | (31,560) | (18,480)
Professional fees | (3,124) | (2,696) | (5,181) | (4,959)
Facility expenses | (1,704) | (4,624) | (3,371) | (9,763)
Consumables | (697) | (3,472) | (1,633) | (6,684)
Other segment items(1) | (1,945) | (631) | (2,979) | (8,063)
Loss from operations | $ (32,326) | $ (32,366) | $ (66,636) | $ (75,386)
Other segment items description | Other segment items included in segment operating loss include costs related to intellectual property, information technology and insurance offset by income related to payments received from European authorities to subsidize the Company’s research and development in the Netherlands. | Other segment items included in segment operating loss include costs related to intellectual property, information technology and insurance offset by income related to payments received from European authorities to subsidize the Company’s research and development in the Netherlands. | Other segment items included in segment operating loss include costs related to intellectual property, information technology and insurance offset by income related to payments received from European authorities to subsidize the Company’s research and development in the Netherlands. | Other segment items included in segment operating loss include costs related to intellectual property, information technology and insurance offset by income related to payments received from European authorities to subsidize the Company’s research and development in the Netherlands.
Material Reconciling | Single Reportable Segment |  |  |  |
Segment reporting |  |  |  |
Depreciation and amortization expense | $ (3,630) | $ (2,670) | $ (8,157) | $ (5,299)
Share-based compensation expense | (5,084) | (6,880) | (9,494) | (14,071)
Fair value loss - contingent consideration | (2,254) | 1,786 | (3,470) | 1,621
Foreign currency gains / (losses), net | 18,638 | (989) | 25,810 | (2,134)
Interest income | 3,524 | 5,805 | 7,651 | 12,313
Interest expense - Royalty Financing Agreement | (13,770) | (12,438) | (27,079) | (24,839)
Interest expense - Hercules debt facility | (1,821) | (3,719) | (3,621) | (7,415)
Other reconciling items | $ (571) | $ (3,880) | $ 4,561 | $ (5,103)

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