XML 41 R31.htm IDEA: XBRL DOCUMENT
v3.25.2

Segment Reporting (Tables) | 6 Months Ended
--- | ---
Jun. 30, 2025
Segment Reporting |
Schedule of segment reporting | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three months ended June 30, | ​ | Six months ended June 30,
​ |  | 2025 |  | 2024 | ​ | 2025 |  | 2024
​ | ​ | (in thousands) | ​ | (in thousands)
Revenue | ​ | $ | 5,262 | ​ | $ | 11,126 | ​ | $ | 6,829 | ​ | $ | 19,611
Less: | ​ |  | ​ | ​ | ​ | ​ | ​ |  | ​ | ​ | ​ | ​
Employee related expenses | ​ |  | (14,525) | ​ |  | (22,665) | ​ |  | (28,741) | ​ |  | (47,048)
Laboratory and development expenses | ​ | ​ | (15,593) | ​ | ​ | (9,404) | ​ | ​ | (31,560) | ​ | ​ | (18,480)
Professional fees | ​ | ​ | (3,124) | ​ | ​ | (2,696) | ​ | ​ | (5,181) | ​ | ​ | (4,959)
Facility expenses | ​ | ​ | (1,704) | ​ | ​ | (4,624) | ​ | ​ | (3,371) | ​ | ​ | (9,763)
Consumables | ​ | ​ | (697) | ​ | ​ | (3,472) | ​ | ​ | (1,633) | ​ | ​ | (6,684)
Other segment items(1) | ​ | ​ | (1,945) | ​ | ​ | (631) | ​ | ​ | (2,979) | ​ | ​ | (8,063)
Segment operating loss | ​ | ​ | (32,326) | ​ | ​ | (32,366) | ​ | ​ | (66,636) | ​ | ​ | (75,386)
Reconciliation | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Depreciation and amortization expense | ​ | ​ | (3,630) | ​ | ​ | (2,670) | ​ | ​ | (8,157) | ​ | ​ | (5,299)
Share-based compensation expense | ​ | ​ | (5,084) | ​ | ​ | (6,880) | ​ | ​ | (9,494) | ​ | ​ | (14,071)
Fair value loss - contingent consideration | ​ | ​ | (2,254) | ​ | ​ | 1,786 | ​ | ​ | (3,470) | ​ | ​ | 1,621
Foreign currency gains / (losses), net | ​ | ​ | 18,638 | ​ | ​ | (989) | ​ | ​ | 25,810 | ​ | ​ | (2,134)
Interest income | ​ | ​ | 3,524 | ​ | ​ | 5,805 | ​ | ​ | 7,651 | ​ | ​ | 12,313
Interest expense - Royalty Financing Agreement | ​ | ​ | (13,770) | ​ |  | (12,438) | ​ | ​ | (27,079) | ​ |  | (24,839)
Interest expense - Hercules debt facility | ​ | ​ | (1,821) | ​ | ​ | (3,719) | ​ | ​ | (3,621) | ​ | ​ | (7,415)
Other reconciling items | ​ | ​ | (571) | ​ | ​ | (3,880) | ​ | ​ | 4,561 | ​ | ​ | (5,103)
Consolidated loss before income tax expense | ​ | $ | (37,294) | ​ | $ | (55,351) | ​ | $ | (80,435) | ​ | $ | (120,313)
​
| (1) | Other segment items included in segment operating loss include costs related to intellectual property, information technology and insurance offset by income related to payments received from European authorities to subsidize the Company’s research and development in the Netherlands.

X
- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
Name: | us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SegmentReportingAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration