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Long-term debt (Details) - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 6 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Jul. 31, 2024 | Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024 | Jan. 05, 2027 | Dec. 01, 2025 | Dec. 31, 2024
2023 Amended Facility |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Repayments of long term lines of credit | $ 50.0 |  |  |  |  |  |  |
Outstanding debt | 100.0 |  |  |  |  |  |  |
Back-end fees paid | $ 3.1 |  |  |  |  |  |  |
2024 Amended Facility |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Outstanding debt |  | $ 50.0 |  | $ 50.0 |  |  |  |
Interest rate (as a percent) |  | 7.95% |  | 7.95% |  |  |  |
Variable interest rate basis |  |  |  | 7.95% |  |  |  |
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration] |  |  |  | us-gaap:PrimeRateMember |  |  |  |
Discount rate (as a percent) |  | 3.25% |  | 3.25% |  |  |  |
Amortized cost net of discount and debt issuance costs |  | $ 52.3 |  | $ 52.3 |  |  |  | $ 51.9
Foreign currency gain |  | 4.3 |  | 6.4 |  |  |  |
Foreign currency loss |  |  | $ 0.7 |  | $ 3.0 |  |  |
Interest expense recorded |  | $ 1.8 | $ 3.7 | $ 3.6 | $ 7.4 |  |  |
2024 Amended Facility | Forecast |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Back-end fees |  |  |  |  |  | $ 0.6 | $ 2.4 |
Venture debt loan facility | 2024 Amended Facility |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Minimum percentage of cash and cash equivalents required to keep in U.S. bank accounts |  |  |  | 30.00% |  |  |  |
Assets pledged to secure facilities by directly or indirectly |  |  |  | $ 584.9 |  |  |  |
Assets not being pledged to secure facilities by directly or indirectly |  |  |  | 69.7 |  |  |  |
Venture debt loan facility | 2024 Amended Facility | uniQure France |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Assets not being pledged to secure facilities by directly or indirectly |  |  |  | $ 89.8 |  |  |  |
Venture debt loan facility | 2024 Amended Facility | Maximum |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Minimum percentage of cash and cash equivalents required to keep in U.S. bank accounts |  |  |  | 100.00% |  |  |  |
Venture debt loan facility | 2024 Amended Facility | Minimum |  |  |  |  |  |  |  |
Long-term Debt |  |  |  |  |  |  |  |
Minimum percentage of cash and cash equivalents required to keep in U.S. bank accounts |  |  |  | 65.00% |  |  |  |

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