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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Cash flows from operating activities:    
Net loss $ (23,280) $ (23,599)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 586 359
Equity-based compensation 3,432 1,571
Amortization of investment securities (694)  
Amortization of operating lease right-of-use asset 492  
Deferred payroll tax credit   190
Change in operating assets and liabilities:    
Prepaid expenses and other current assets (1,091) (753)
Accounts payable (1,028) 464
Accrued expenses (1,771) 191
Deferred rent   (15)
Operating lease liabilities (378)  
Deferred revenue (8,145)  
Other liabilities (59) 82
Net cash used in operating activities (31,936) (21,510)
Cash flows from investing activities:    
Purchase of property and equipment (1,279) (192)
Purchase of marketable securities (77,297)  
Sales and maturities of marketable securities 67,300 1,498
Net cash (used in) provided by investing activities (11,276) 1,306
Cash flows from financing activities:    
Principal payments on loan payable (365) (333)
Proceeds from sale of common stock, net of issuance costs 42,220 79,137
Proceeds from stock option exercises 92  
Other (6)  
Net cash provided by financing activities 41,941 78,804
Net (decrease) increase in cash and cash equivalents and restricted cash (1,271) 58,600
Cash and cash equivalents and restricted cash, beginning of period 115,274 56,666
Cash and cash equivalents and restricted cash, end of period 114,003 115,266
Supplemental disclosure of non-cash items:    
Property and equipment purchases in accounts payable 27  
Offering costs in accounts payable and accrued expenses 198 1,302
Operating lease right-of-use asset obtained in exchange for operating lease obligation 5,349  
Supplemental cash flow information:    
Cash paid for interest $ 6 $ 19