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Net Loss per Share (Details) - shares | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020
Anti-dilutive securities |  |
Pre funded warrants exercised during period | 0 |
Anti-dilutive securities excluded from the calculation of net loss per share | 4,058,301 | 3,737,900
Restricted stock awards |  |
Anti-dilutive securities |  |
Anti-dilutive securities excluded from the calculation of net loss per share |  | 57,969
Restricted Stock Units |  |
Anti-dilutive securities |  |
Anti-dilutive securities excluded from the calculation of net loss per share | 314,901 |
Stock Options |  |
Anti-dilutive securities |  |
Anti-dilutive securities excluded from the calculation of net loss per share | 3,743,400 | 3,679,931

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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