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Income Taxes - Reconciliation (Details) | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020
Effective income tax rate |  |
Tax effected at statutory rate | 21.00% | 21.00%
State taxes | 6.80% | 6.80%
Stock compensation | 0.90% | 1.60%
Non deductible expenses | (1.60%) | (2.40%)
Federal research and development credits | 6.50% | 7.90%
Other | (1.50%) | (0.50%)
Change in valuation allowance | (32.10%) | (34.40%)

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