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Common Stock - (Details) - USD ($) $ / shares in Units, $ in Thousands |  |  |  | 2 Months Ended | 12 Months Ended
--- | --- | --- | --- | --- | ---
Oct. 28, 2021 | Nov. 02, 2020 | Oct. 28, 2020 | Jul. 31, 2019 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Sale of common shares, net of issuance costs (in shares) |  |  | 3,717,948 | 3,450,000 |  |  |
Proceeds from sale of common shares and pre-funded warrants, net of issuance costs |  | $ 215,900 |  |  | $ 13,095 | $ 215,922 | $ 48,300
Purchase price (in dollars per share) |  |  | $ 39.00 | $ 15.00 |  |  |
Warrant to purchase |  |  | 2,179,487 |  |  |  |
Pre-funded warrants (in dollars per share) |  |  | $ 38.9999 |  |  |  |
Warrant purchase price (in dollars per share) |  |  | $ 0.0001 |  |  |  |
Proceeds from stock before issuance costs |  |  | $ 230,000 |  |  |  |
Pre funded warrants exercised during period |  |  |  |  | 0 |  |
ATM Offering |  |  |  |  |  |  |
Subsidiary, Sale of Stock [Line Items] |  |  |  |  |  |  |
Aggregate offering price | $ 150,000 |  |  |  |  |  |
Sale of common shares, net of issuance costs (in shares) | 500,000 |  |  |  |  |  |
Proceeds from sale of common shares and pre-funded warrants, net of issuance costs | $ 13,100 |  |  |  |  |  |

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