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Common Stock - (Details) - USD ($)
$ / shares in Units, $ in Thousands
 2 Months Ended 12 Months Ended
Oct. 28, 2021
Nov. 02, 2020
Oct. 28, 2020
Jul. 31, 2019
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Subsidiary, Sale of Stock [Line Items]              
Sale of common shares, net of issuance costs (in shares)     3,717,948 3,450,000      
Proceeds from sale of common shares and pre-funded warrants, net of issuance costs   $ 215,900     $ 13,095 $ 215,922 $ 48,300
Purchase price (in dollars per share)     $ 39.00 $ 15.00      
Warrant to purchase     2,179,487        
Pre-funded warrants (in dollars per share)     $ 38.9999        
Warrant purchase price (in dollars per share)     $ 0.0001        
Proceeds from stock before issuance costs     $ 230,000        
Pre funded warrants exercised during period         0    
ATM Offering              
Subsidiary, Sale of Stock [Line Items]              
Aggregate offering price $ 150,000            
Sale of common shares, net of issuance costs (in shares) 500,000            
Proceeds from sale of common shares and pre-funded warrants, net of issuance costs $ 13,100