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Income Taxes - Reconciliation (Details)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Effective income tax rate
Tax effected at statutory rate	21.00%	21.00%
State taxes	6.80%	6.80%
Stock compensation	0.90%	1.60%
Non deductible expenses	(1.60%)	(2.40%)
Federal research and development credits	6.50%	7.90%
Other	(1.50%)	(0.50%)
Change in valuation allowance	(32.10%)	(34.40%)

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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to research tax credit.

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