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Commitments and Contingencies (Details) - USD ($) $ in Thousands		1 Months Ended		12 Months Ended
	Oct. 05, 2020	Nov. 30, 2019	Feb. 28, 2018	Dec. 31, 2021	Dec. 31, 2020	Mar. 31, 2015
Leased assets
Rent for facility lease				$ 8,600	$ 3,200
Letter of credit				2,500
Sublease income				2,300
Lease Cost:
Operating lease cost				8,642
Variable lease cost				2,256
Total lease cost				10,898
Operating cash flows used for operating leases				$ 8,880
Weighted average remaining lease term				3 years 4 months 24 days
Weighted average incremental borrowing rate				7.50%
Payment made on commitment				$ 2,000
Payment commitment				3,700
Antibody library expense				$ 3,700
620 Memorial Drive, Cambridge MA
Leased assets
Term of lease						5 years
Option to extend the term			true
Renewal term			5 years
Sublease annual base rent	$ 1,900
620 Memorial Drive, Cambridge MA | Financing receivable, lower range of payment terms
Leased assets
Rent for facility lease			$ 1,400
620 Memorial Drive, Cambridge MA | Financing receivable, upper range of payment terms
Leased assets
Rent for facility lease			$ 1,700
301 Binney St, Cambridge MA
Leased assets
Option to extend the term		true
Renewal term		2 years
Base rent		$ 6,900
Annual upward adjustment (as a percent)		3.50%
Incentive to lease		$ 14,100
Letter of credit		$ 2,300

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