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Insider Trading Arrangements
 3 Months Ended
Mar. 31, 2026
shares
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement Rule 10b5-1 Trading Arrangements

 

On February 6, 2026, Ian Somaiya, our Chief Financial Officer terminated a Rule 10b5-1 trading arrangement intended to satisfy the affirmative defense of Rule 10b5-1(c) that he initially adopted on September 30, 2025 and that provided for the potential sale of up to 200,000 Ordinary Shares, subject to certain price thresholds and other conditions. 100,000 Ordinary Shares were sold under this arrangement prior to its termination. On March 27, 2026, Mr. Somaiya adopted a Rule 10b5-1 trading arrangement intended to satisfy the affirmative defense of Rule 10b5-1(c) providing for the potential sale of up to 200,000 Ordinary Shares, subject to certain price thresholds and other conditions. The arrangement's expiration date is June 30, 2027.

 

On February 23, 2026, Louise Kooij, our Chief Accounting Officer, adopted a Rule 10b5-1 trading arrangement intended to satisfy the affirmative defense of Rule 10b5-1(c) providing for the potential sale of up to 210,000 Ordinary Shares, subject to certain price thresholds and other conditions. The arrangement's expiration date is December 30, 2026.

 

On February 27, 2026, Michael Davidson, our Chief Executive Officer, terminated a Rule 10b5-1 trading arrangement intended to satisfy the affirmative defense of Rule 10b5-1(c) that he initially adopted on September 29,

2025 and that provided for the potential sale of up to 750,000 Ordinary Shares, subject to certain price thresholds and other conditions. 306,293 Ordinary Shares were sold under this arrangement prior to its termination.

 

On March 31, 2026, Futurum B.V., an entity affiliated with John Kastelein, our Chief Scientific Officer, adopted a Rule 10b5-1 trading arrangement intended to satisfy the affirmative defense of Rule 10b5-1(c) providing for the potential sale of up to 250,000 Ordinary Shares, subject to certain price thresholds and other conditions. The arrangement's expiration date is June 30, 2027.

 

Other than as discussed above, during the three months ended March 31, 2026, none of our directors or officers (as defined in Rule 16a-1(f) promulgated under the Exchange Act) adopted or terminated a Rule 10b5-1 trading arrangement (as defined in Item 408(a)(1)(i) of Regulation S-K) or a non-10b5-1 trading arrangement (as defined in Item 408(c) of Regulation S-K).
Ian Somaiya  
Trading Arrangements, by Individual  
Name Ian Somaiya
Title Chief Financial Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date September 30, 2025
Rule 10b5-1 Arrangement Terminated true
Termination Date February 6, 2026
Arrangement Duration 130 days
Aggregate Available 200,000
Mr. Somaiya  
Trading Arrangements, by Individual  
Name Mr. Somaiya
Rule 10b5-1 Arrangement Adopted true
Adoption Date March 27, 2026
Rule 10b5-1 Arrangement Terminated true
Termination Date June 30, 2027
Arrangement Duration 461 days
Aggregate Available 200,000
Louise Kooij  
Trading Arrangements, by Individual  
Name Louise Kooij
Title Chief Accounting Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date February 23, 2026
Rule 10b5-1 Arrangement Terminated true
Termination Date December 30, 2026
Arrangement Duration 311 days
Aggregate Available 210,000
Michael Davidson  
Trading Arrangements, by Individual  
Name Michael Davidson
Title Chief Executive Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date September 29, 2025
Rule 10b5-1 Arrangement Terminated true
Termination Date February 27, 2026
Arrangement Duration 152 days
Aggregate Available 750,000
John Kastelein  
Trading Arrangements, by Individual  
Name John Kastelein
Title Chief Scientific Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date March 31, 2026
Rule 10b5-1 Arrangement Terminated true
Termination Date June 30, 2027
Arrangement Duration 457 days
Aggregate Available 250,000
Other Directors or Officers  
Trading Arrangements, by Individual  
Rule 10b5-1 Arrangement Adopted false
Non-Rule 10b5-1 Arrangement Adopted false
Rule 10b5-1 Arrangement Terminated false
Non-Rule 10b5-1 Arrangement Terminated false