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Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended | 15 Months Ended
--- | --- | ---
Mar. 31, 2024 | Mar. 31, 2023 | Mar. 31, 2024
Cash flows from operating activities |  |  |
Net loss | $ (27,356) | $ (19,531) |
Adjustments to reconcile net loss to net cash used in operating activities |  |  |
Amortization of investment premiums | (2,821) | (389) |
Amortization of financing costs | 28 | 28 |
Stock-based compensation | 7,981 | 3,569 |
Amortization of right-of-use assets | 74 | 72 |
Interest expense related to operating lease liability | 9 | 12 |
Changes in operating assets and liabilities: |  |  |
Prepaid expenses and other current assets | 1,748 | (2,258) |
Accrued interest, net of interest receivable on maturity of investments | 655 | 243 |
Accounts payable | (2,287) | (4,732) |
Accrued expenses | 15,923 | (1,572) |
Lease liability | (88) | (85) |
Net cash used in operating activities | (6,134) | (24,643) |
Cash flows from investing activities |  |  |
Purchases of investments | (596,601) | (57,395) |
Proceeds from maturities of investments | 136,809 | 59,593 |
Net cash (used in) provided by investing activities | (459,792) | 2,198 |
Cash flows from financing activities |  |  |
Public offering, net of offering costs | 597,119 | (37) |
Value of shares withheld related to employee tax withholding | (42,101) | (1,714) |
Proceeds from option exercises | 4,361 | 3,966 |
ATM offering, net of fees | 46,658 | 1,969 |
Net cash provided by financing activities | 606,037 | 4,184 |
Net Increase (decrease) in cash and cash equivalents | 140,111 | (18,261) |
Cash and cash equivalents beginning of period | 55,516 | 36,632 | $ 36,632
Effect of exchange rate changes on cash | (48) | (9) |
Cash and cash equivalents end of period | 195,579 | 18,362 | $ 195,579
Supplemental disclosure of non-cash investing and financing transactions |  |  |
Unpaid deferred public offering and other financing costs | $ 69 | $ 52 |

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- Definition Amount of cash and cash equivalents, and cash and cash equivalents restricted to withdrawal or usage; including, but not limited to, disposal group and discontinued operations. Cash includes, but is not limited to, currency on hand, demand deposits with banks or financial institutions, and other accounts with general characteristics of demand deposits. Cash equivalents include, but are not limited to, short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 230 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 8 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482913/230-10-50-8 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 230 -SubTopic 10 -Name Accounting Standards Codification -Section 45 -Paragraph 24 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482740/230-10-45-24 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482740/230-10-45-4 + Details
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