    <SEC-DOCUMENT>0001933414-26-000073-index.html : 20260410
    <SEC-HEADER>0001933414-26-000073.hdr.sgml : 20260410
    <ACCEPTANCE-DATETIME>20260410162405
    ACCESSION NUMBER:		0001933414-26-000073
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20251231
    FILED AS OF DATE:		20260410
    DATE AS OF CHANGE:		20260410
    EFFECTIVENESS DATE:		20260410

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Mineralys Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0001933414
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-41614
    		FILM NUMBER:		26855191

    	BUSINESS ADDRESS:
    		STREET 1:		150 N. RADNOR CHESTER RD.
    		STREET 2:		SUITE F200
    		CITY:			RADNOR
    		STATE:			PA
    		ZIP:			19087
    		BUSINESS PHONE:		(888) 378-6240

    	MAIL ADDRESS:
    		STREET 1:		150 N. RADNOR CHESTER RD.
    		STREET 2:		SUITE F200
    		CITY:			RADNOR
    		STATE:			PA
    		ZIP:			19087
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>mineralystherapeutics_2026.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: mineralystherapeutics_2026.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>