<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:e2c974a5-4c2c-4c4a-a613-a30026151d03,g:64595ea2-724e-4728-8d67-4dfc6a9ab049-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member"/>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/CondensedConsolidatedStatementsofIncomeandComprehensiveIncome" xlink:type="simple" xlink:href="pbh-20250630.xsd#CondensedConsolidatedStatementsofIncomeandComprehensiveIncome"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/CondensedConsolidatedStatementsofIncomeandComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_87cd74b3-0cfa-47f0-8636-95e7aff78ef6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_StatementTable_87cd74b3-0cfa-47f0-8636-95e7aff78ef6" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_1ab5201c-6734-4f29-8547-83e01f4017e2" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_87cd74b3-0cfa-47f0-8636-95e7aff78ef6" xlink:to="loc_srt_ProductOrServiceAxis_1ab5201c-6734-4f29-8547-83e01f4017e2" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_1ab5201c-6734-4f29-8547-83e01f4017e2_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_1ab5201c-6734-4f29-8547-83e01f4017e2" xlink:to="loc_srt_ProductsAndServicesDomain_1ab5201c-6734-4f29-8547-83e01f4017e2_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_86b02247-ed20-44e8-bea7-59df99e906af" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_1ab5201c-6734-4f29-8547-83e01f4017e2" xlink:to="loc_srt_ProductsAndServicesDomain_86b02247-ed20-44e8-bea7-59df99e906af" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_e9bf621c-2d42-4fd2-82e0-39e71011ca4e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_86b02247-ed20-44e8-bea7-59df99e906af" xlink:to="loc_us-gaap_ProductMember_e9bf621c-2d42-4fd2-82e0-39e71011ca4e" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductAndServiceOtherMember_8a594526-2a7c-45a6-9ff8-2a5958e4ece8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductAndServiceOtherMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_86b02247-ed20-44e8-bea7-59df99e906af" xlink:to="loc_us-gaap_ProductAndServiceOtherMember_8a594526-2a7c-45a6-9ff8-2a5958e4ece8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_b0728db6-8168-4c0e-bfad-f8fd66c7f854" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenuesAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_RevenuesAbstract_b0728db6-8168-4c0e-bfad-f8fd66c7f854" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_f0119cd7-c107-45de-b783-aafba741eb13" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_RevenuesAbstract_b0728db6-8168-4c0e-bfad-f8fd66c7f854" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_f0119cd7-c107-45de-b783-aafba741eb13" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_73971b3a-4f6b-4328-b7c7-6a5600de517a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSoldAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_73971b3a-4f6b-4328-b7c7-6a5600de517a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_CostOfSalesExclusiveOfDepreciation_593d2726-0e90-4e30-857a-27a76bd6debe" xlink:href="pbh-20250630.xsd#pbh_CostOfSalesExclusiveOfDepreciation"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_73971b3a-4f6b-4328-b7c7-6a5600de517a" xlink:to="loc_pbh_CostOfSalesExclusiveOfDepreciation_593d2726-0e90-4e30-857a-27a76bd6debe" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSoldDepreciation_7fd6598a-e442-4013-bae9-22e5ad623cc4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfGoodsAndServicesSoldDepreciation"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_73971b3a-4f6b-4328-b7c7-6a5600de517a" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSoldDepreciation_7fd6598a-e442-4013-bae9-22e5ad623cc4" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfRevenue_408ede06-bafd-48a9-89d6-2799b48b81e5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfRevenue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CostOfGoodsAndServicesSoldAbstract_73971b3a-4f6b-4328-b7c7-6a5600de517a" xlink:to="loc_us-gaap_CostOfRevenue_408ede06-bafd-48a9-89d6-2799b48b81e5" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_1874cac8-b3cb-4478-8882-3799d512415c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_GrossProfit_1874cac8-b3cb-4478-8882-3799d512415c" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_50f8dd32-048b-4982-a6f6-ba86d8c6428d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_OperatingExpensesAbstract_50f8dd32-048b-4982-a6f6-ba86d8c6428d" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingAndAdvertisingExpense_129ddf36-00b0-458d-8644-d0c5df9715ec" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MarketingAndAdvertisingExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OperatingExpensesAbstract_50f8dd32-048b-4982-a6f6-ba86d8c6428d" xlink:to="loc_us-gaap_MarketingAndAdvertisingExpense_129ddf36-00b0-458d-8644-d0c5df9715ec" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_9455a3fb-6a52-43a4-8ecd-b2a360bb3cc4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OperatingExpensesAbstract_50f8dd32-048b-4982-a6f6-ba86d8c6428d" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_9455a3fb-6a52-43a4-8ecd-b2a360bb3cc4" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherDepreciationAndAmortization_dc3dea2a-95f7-419c-8379-195316da8c6a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherDepreciationAndAmortization"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OperatingExpensesAbstract_50f8dd32-048b-4982-a6f6-ba86d8c6428d" xlink:to="loc_us-gaap_OtherDepreciationAndAmortization_dc3dea2a-95f7-419c-8379-195316da8c6a" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_21a622b5-b96d-4fea-b80e-e012236edece" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingExpenses"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OperatingExpensesAbstract_50f8dd32-048b-4982-a6f6-ba86d8c6428d" xlink:to="loc_us-gaap_OperatingExpenses_21a622b5-b96d-4fea-b80e-e012236edece" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_d5286f96-dd5b-44c8-a975-bea7a5c138ad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_OperatingIncomeLoss_d5286f96-dd5b-44c8-a975-bea7a5c138ad" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_8faa16b4-708e-4a6f-b39c-2e69bf774711" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpenseAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_8faa16b4-708e-4a6f-b39c-2e69bf774711" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_0d4f9d67-fcf4-4066-a59a-22991dc3cfae" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_InterestIncomeExpenseNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_8faa16b4-708e-4a6f-b39c-2e69bf774711" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_0d4f9d67-fcf4-4066-a59a-22991dc3cfae" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_cfee4819-28da-402b-bc19-3e376c79ee75" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_8faa16b4-708e-4a6f-b39c-2e69bf774711" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_cfee4819-28da-402b-bc19-3e376c79ee75" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_TotalOtherIncomeExpense_845e79db-d969-4d52-8593-525728ae5b1d" xlink:href="pbh-20250630.xsd#pbh_TotalOtherIncomeExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_8faa16b4-708e-4a6f-b39c-2e69bf774711" xlink:to="loc_pbh_TotalOtherIncomeExpense_845e79db-d969-4d52-8593-525728ae5b1d" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossAttributableToParent_96ac7e8f-d11e-4ba3-8123-d3b71295d757" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeLossAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_IncomeLossAttributableToParent_96ac7e8f-d11e-4ba3-8123-d3b71295d757" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_61fd29f7-582e-419a-8c99-a09d17ac2a5d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_61fd29f7-582e-419a-8c99-a09d17ac2a5d" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_020dd533-d462-4dd7-92fe-28617e3396e8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_NetIncomeLoss_020dd533-d462-4dd7-92fe-28617e3396e8" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareAbstract_c5b9d54d-38b8-4cef-b079-5cec740247a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EarningsPerShareAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_EarningsPerShareAbstract_c5b9d54d-38b8-4cef-b079-5cec740247a0" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_448c18f3-4a70-48f0-97ad-1435b8ff4264" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareAbstract_c5b9d54d-38b8-4cef-b079-5cec740247a0" xlink:to="loc_us-gaap_EarningsPerShareBasic_448c18f3-4a70-48f0-97ad-1435b8ff4264" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_b485e025-51f3-4a56-b96d-3efde1c64106" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EarningsPerShareAbstract_c5b9d54d-38b8-4cef-b079-5cec740247a0" xlink:to="loc_us-gaap_EarningsPerShareDiluted_b485e025-51f3-4a56-b96d-3efde1c64106" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_WeightedAverageSharesOutstandingAbstract_8f16dbbb-3795-4a63-bc38-da9148978175" xlink:href="pbh-20250630.xsd#pbh_WeightedAverageSharesOutstandingAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_pbh_WeightedAverageSharesOutstandingAbstract_8f16dbbb-3795-4a63-bc38-da9148978175" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0cb5b225-c52c-469c-bd49-70184f59627c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_WeightedAverageSharesOutstandingAbstract_8f16dbbb-3795-4a63-bc38-da9148978175" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0cb5b225-c52c-469c-bd49-70184f59627c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_4cb76799-ae44-405a-b1ec-d9fef21a2818" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_WeightedAverageSharesOutstandingAbstract_8f16dbbb-3795-4a63-bc38-da9148978175" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_4cb76799-ae44-405a-b1ec-d9fef21a2818" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_4c5aa393-090b-46b0-ab4a-8703f4986df8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTaxAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_4c5aa393-090b-46b0-ab4a-8703f4986df8" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_8aff45ee-c371-4db3-b332-15472a033458" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_4c5aa393-090b-46b0-ab4a-8703f4986df8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_8aff45ee-c371-4db3-b332-15472a033458" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_1dd7980a-a867-4d3e-88df-9f7a51252519" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTaxAbstract_4c5aa393-090b-46b0-ab4a-8703f4986df8" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_1dd7980a-a867-4d3e-88df-9f7a51252519" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_45593a4e-a2ba-43d8-9780-4012b56e7e30" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_303d3afb-1de9-4b06-b39f-45d7a10dd320" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_45593a4e-a2ba-43d8-9780-4012b56e7e30" xlink:type="arc" order="12"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/CondensedConsolidatedStatementsofChangesinStockholdersEquity" xlink:type="simple" xlink:href="pbh-20250630.xsd#CondensedConsolidatedStatementsofChangesinStockholdersEquity"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/CondensedConsolidatedStatementsofChangesinStockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_75e7f25d-86ff-437f-b4d7-690be7fb5114" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_7aa4e189-91ca-4074-88eb-f91f73b64f7f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_StatementLineItems_75e7f25d-86ff-437f-b4d7-690be7fb5114" xlink:to="loc_us-gaap_StatementTable_7aa4e189-91ca-4074-88eb-f91f73b64f7f" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_8d5f7150-705e-4929-a07b-5d6f9f929e56" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_StatementTable_7aa4e189-91ca-4074-88eb-f91f73b64f7f" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_8d5f7150-705e-4929-a07b-5d6f9f929e56" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_8d5f7150-705e-4929-a07b-5d6f9f929e56_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_8d5f7150-705e-4929-a07b-5d6f9f929e56" xlink:to="loc_us-gaap_EquityComponentDomain_8d5f7150-705e-4929-a07b-5d6f9f929e56_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_8d5f7150-705e-4929-a07b-5d6f9f929e56" xlink:to="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_bc7cee1d-7185-4236-8fb2-9f707607a7ce" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:to="loc_us-gaap_CommonStockMember_bc7cee1d-7185-4236-8fb2-9f707607a7ce" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_664ded1b-36b7-4307-96ef-2988a300ed83" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_664ded1b-36b7-4307-96ef-2988a300ed83" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonMember_8f3d4683-1808-453e-b721-f143e7258999" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockCommonMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:to="loc_us-gaap_TreasuryStockCommonMember_8f3d4683-1808-453e-b721-f143e7258999" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_60fbda7a-26fb-4d8f-b04b-6fd993e566fc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_60fbda7a-26fb-4d8f-b04b-6fd993e566fc" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_34d9a9e5-d35b-44a4-a1f0-1a18c87544e0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RetainedEarningsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_f66e1d6a-233f-46bf-8584-78cb9d495c63" xlink:to="loc_us-gaap_RetainedEarningsMember_34d9a9e5-d35b-44a4-a1f0-1a18c87544e0" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_StatementLineItems_75e7f25d-86ff-437f-b4d7-690be7fb5114" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_1544920b-40a8-47cc-9c0a-2aeb37a492c1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_1544920b-40a8-47cc-9c0a-2aeb37a492c1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_4bd2b8ad-ee27-453b-a85d-e8a325f61868" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_StockholdersEquity_4bd2b8ad-ee27-453b-a85d-e8a325f61868" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonShares_4cbd5d17-13fc-47b4-9400-577c718448b9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockCommonShares"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_TreasuryStockCommonShares_4cbd5d17-13fc-47b4-9400-577c718448b9" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_750285e7-6c5b-4764-b7e7-28f26204ae23" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueShareBasedCompensation_750285e7-6c5b-4764-b7e7-28f26204ae23" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_3e6d6ef4-dda4-4858-a908-44d5bef519ad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_3e6d6ef4-dda4-4858-a908-44d5bef519ad" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_df977989-2d3f-4608-839d-59d1373e52ac" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_df977989-2d3f-4608-839d-59d1373e52ac" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_5099b848-e20f-47eb-bd45-47f766c04c9d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_5099b848-e20f-47eb-bd45-47f766c04c9d" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_c658c11d-0ec4-4afe-928b-b985c624e3a7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_c658c11d-0ec4-4afe-928b-b985c624e3a7" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_851b30b0-c71d-498f-9690-038c6e06d9b7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockSharesAcquired"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_851b30b0-c71d-498f-9690-038c6e06d9b7" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_884d6ee2-8688-4987-a4c0-94a988cb4ff2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_884d6ee2-8688-4987-a4c0-94a988cb4ff2" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_4cea0f07-eb39-47e1-a405-a0205f39fab9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_NetIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_NetIncomeLoss_4cea0f07-eb39-47e1-a405-a0205f39fab9" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_47891b98-0022-47e5-90e1-3bbfbf8e006c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_8ad73e63-13ff-4ffa-98bd-2a8dccc21c1d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_47891b98-0022-47e5-90e1-3bbfbf8e006c" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_4f696e03-4790-4f74-81e3-5110a31eae74" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_b62dd7dd-b18f-45ce-b572-07ff36137db9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockCommonShares_cb1a9845-2e93-4fe7-9ce7-dcc8b3d3b5b5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockCommonShares"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/GoodwillScheduleofChangesDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#GoodwillScheduleofChangesDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/GoodwillScheduleofChangesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillLineItems_ad3cbd5a-c236-447a-8597-3bbe09579152" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfGoodwillTable_9d6aa19d-7650-4453-aab8-9df26fe7ee72" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfGoodwillTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_GoodwillLineItems_ad3cbd5a-c236-447a-8597-3bbe09579152" xlink:to="loc_us-gaap_ScheduleOfGoodwillTable_9d6aa19d-7650-4453-aab8-9df26fe7ee72" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_ebdb7fb8-5508-410e-a845-e94867cd1eb5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfGoodwillTable_9d6aa19d-7650-4453-aab8-9df26fe7ee72" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_ebdb7fb8-5508-410e-a845-e94867cd1eb5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_ebdb7fb8-5508-410e-a845-e94867cd1eb5_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_ebdb7fb8-5508-410e-a845-e94867cd1eb5" xlink:to="loc_us-gaap_SegmentDomain_ebdb7fb8-5508-410e-a845-e94867cd1eb5_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_ce304ae6-51dc-440f-a9aa-723f6747ae0b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_ebdb7fb8-5508-410e-a845-e94867cd1eb5" xlink:to="loc_us-gaap_SegmentDomain_ce304ae6-51dc-440f-a9aa-723f6747ae0b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_NorthAmericanOTCHealthcareMember_700fe769-877d-410a-9152-1b349b61b9a0" xlink:href="pbh-20250630.xsd#pbh_NorthAmericanOTCHealthcareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_ce304ae6-51dc-440f-a9aa-723f6747ae0b" xlink:to="loc_pbh_NorthAmericanOTCHealthcareMember_700fe769-877d-410a-9152-1b349b61b9a0" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_InternationalOTCHealthcareMember_ca6fa68a-e91d-41bf-96dd-480622215411" xlink:href="pbh-20250630.xsd#pbh_InternationalOTCHealthcareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_ce304ae6-51dc-440f-a9aa-723f6747ae0b" xlink:to="loc_pbh_InternationalOTCHealthcareMember_ca6fa68a-e91d-41bf-96dd-480622215411" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillRollForward_c2c889c8-7419-4649-894d-31679572a74b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillLineItems_ad3cbd5a-c236-447a-8597-3bbe09579152" xlink:to="loc_us-gaap_GoodwillRollForward_c2c889c8-7419-4649-894d-31679572a74b" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillGross_7f975d99-d326-48fb-8900-47ecfdda720e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_c2c889c8-7419-4649-894d-31679572a74b" xlink:to="loc_us-gaap_GoodwillGross_7f975d99-d326-48fb-8900-47ecfdda720e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_6637b9c7-997f-402d-a19e-c6863bc245ab" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillImpairedAccumulatedImpairmentLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_c2c889c8-7419-4649-894d-31679572a74b" xlink:to="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_6637b9c7-997f-402d-a19e-c6863bc245ab" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_bb721c39-9f60-485e-bd59-130e4cc37950" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_c2c889c8-7419-4649-894d-31679572a74b" xlink:to="loc_us-gaap_Goodwill_bb721c39-9f60-485e-bd59-130e4cc37950" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_24a04259-c267-4796-84ba-a0db05307400" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillForeignCurrencyTranslationGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GoodwillRollForward_c2c889c8-7419-4649-894d-31679572a74b" xlink:to="loc_us-gaap_GoodwillForeignCurrencyTranslationGainLoss_24a04259-c267-4796-84ba-a0db05307400" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillGross_d50166a0-7247-409b-925f-6490d4ae76a8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillImpairedAccumulatedImpairmentLoss_f2a18119-57db-442a-b913-704557a9d5f4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GoodwillImpairedAccumulatedImpairmentLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_08570242-ea60-4f7e-8951-bdf655003a08" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_Goodwill"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/IntangibleAssetsnetScheduleofActivityAffectingIntangibleAssetsDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#IntangibleAssetsnetScheduleofActivityAffectingIntangibleAssetsDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/IntangibleAssetsnetScheduleofActivityAffectingIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:href="pbh-20250630.xsd#pbh_ScheduleOfIntangibleAssetsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ScheduleOfIntangibleAssetsTable_4b1aa431-3cec-46d8-bb63-065536c0bcca" xlink:href="pbh-20250630.xsd#pbh_ScheduleOfIntangibleAssetsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_pbh_ScheduleOfIntangibleAssetsTable_4b1aa431-3cec-46d8-bb63-065536c0bcca" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_0888da88-6d95-4b0c-b294-a7721fa2662b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsTable_4b1aa431-3cec-46d8-bb63-065536c0bcca" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_0888da88-6d95-4b0c-b294-a7721fa2662b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0888da88-6d95-4b0c-b294-a7721fa2662b_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_0888da88-6d95-4b0c-b294-a7721fa2662b" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_0888da88-6d95-4b0c-b294-a7721fa2662b_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_62209355-8546-4446-9944-7a131ad03ace" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsByMajorClassAxis_0888da88-6d95-4b0c-b294-a7721fa2662b" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_62209355-8546-4446-9944-7a131ad03ace" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_IndefinitelivedTradenamesMember_27c4d426-2401-4ee7-b70d-36f73cbf6f2e" xlink:href="pbh-20250630.xsd#pbh_IndefinitelivedTradenamesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsMajorClassNameDomain_62209355-8546-4446-9944-7a131ad03ace" xlink:to="loc_pbh_IndefinitelivedTradenamesMember_27c4d426-2401-4ee7-b70d-36f73cbf6f2e" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_f248c86d-07ef-4b80-92f1-5fd2856c2b95" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsTable_4b1aa431-3cec-46d8-bb63-065536c0bcca" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_f248c86d-07ef-4b80-92f1-5fd2856c2b95" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_f248c86d-07ef-4b80-92f1-5fd2856c2b95_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_f248c86d-07ef-4b80-92f1-5fd2856c2b95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_f248c86d-07ef-4b80-92f1-5fd2856c2b95_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_29802c41-8af8-4ee3-9490-71ab1d604410" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_f248c86d-07ef-4b80-92f1-5fd2856c2b95" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_29802c41-8af8-4ee3-9490-71ab1d604410" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_FiniteLivedTradenamesandCustomerRelationshipsMember_efd0b2bc-0897-416b-b1e0-2b0874edb0ea" xlink:href="pbh-20250630.xsd#pbh_FiniteLivedTradenamesandCustomerRelationshipsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_29802c41-8af8-4ee3-9490-71ab1d604410" xlink:to="loc_pbh_FiniteLivedTradenamesandCustomerRelationshipsMember_efd0b2bc-0897-416b-b1e0-2b0874edb0ea" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_e699723b-5a67-4959-81c9-62664cfcaa72" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_e699723b-5a67-4959-81c9-62664cfcaa72" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwillAbstract_170b7906-e042-4c42-a51f-bc9ed255c2c1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwillAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsRollForward_e699723b-5a67-4959-81c9-62664cfcaa72" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwillAbstract_170b7906-e042-4c42-a51f-bc9ed255c2c1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_fa88503a-6e26-4db0-9b97-d4ccf6901a03" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwillAbstract_170b7906-e042-4c42-a51f-bc9ed255c2c1" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_fa88503a-6e26-4db0-9b97-d4ccf6901a03" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_9d059bec-4a82-4319-a35e-59b8187fcf28" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwillAbstract_170b7906-e042-4c42-a51f-bc9ed255c2c1" xlink:to="loc_us-gaap_IndefiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_9d059bec-4a82-4319-a35e-59b8187fcf28" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill_c9948154-11ff-43a2-8fe0-ca25adf2ab52" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_cd4137b3-dcc8-4208-b43c-a6627aa11239" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_cd4137b3-dcc8-4208-b43c-a6627aa11239" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_9010d316-205a-4b03-9df9-44862c4bf704" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGrossAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsRollForward_cd4137b3-dcc8-4208-b43c-a6627aa11239" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_9010d316-205a-4b03-9df9-44862c4bf704" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4d16ca1e-6c69-4ea8-ad85-7d728945d996" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_9010d316-205a-4b03-9df9-44862c4bf704" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4d16ca1e-6c69-4ea8-ad85-7d728945d996" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_ecbfb1ec-5496-4211-8031-cfbe6f0cc96f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsGrossAbstract_9010d316-205a-4b03-9df9-44862c4bf704" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsForeignCurrencyTranslationGainLoss_ecbfb1ec-5496-4211-8031-cfbe6f0cc96f" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_4d4b40ca-1178-4baa-beb4-04e8cd4e6418" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsGross"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_IntangibleAssetsRollForward_108f74f9-e058-47ad-8041-a3ad10ca44db" xlink:href="pbh-20250630.xsd#pbh_IntangibleAssetsRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_pbh_IntangibleAssetsRollForward_108f74f9-e058-47ad-8041-a3ad10ca44db" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_IntangibleAssetsGrossAbstract_3ed3a273-51b7-4a81-87f0-272bdd43de21" xlink:href="pbh-20250630.xsd#pbh_IntangibleAssetsGrossAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_IntangibleAssetsRollForward_108f74f9-e058-47ad-8041-a3ad10ca44db" xlink:to="loc_pbh_IntangibleAssetsGrossAbstract_3ed3a273-51b7-4a81-87f0-272bdd43de21" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_aa520bb3-4580-4a11-9160-3d8f286ab2e0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_IntangibleAssetsGrossAbstract_3ed3a273-51b7-4a81-87f0-272bdd43de21" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_aa520bb3-4580-4a11-9160-3d8f286ab2e0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_IntangibleAssetsTranslationAdjustmentsGainLoss_96323d5f-86f5-4d23-92b3-0fbf47359e1c" xlink:href="pbh-20250630.xsd#pbh_IntangibleAssetsTranslationAdjustmentsGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_IntangibleAssetsGrossAbstract_3ed3a273-51b7-4a81-87f0-272bdd43de21" xlink:to="loc_pbh_IntangibleAssetsTranslationAdjustmentsGainLoss_96323d5f-86f5-4d23-92b3-0fbf47359e1c" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_1acdeffd-09a7-44ed-8867-76856b7f6157" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_FinitelivedIntangibleAssetsAccumulatedAmortizationRollForward_0b057ed8-5658-431b-bff5-85e985353c39" xlink:href="pbh-20250630.xsd#pbh_FinitelivedIntangibleAssetsAccumulatedAmortizationRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_pbh_FinitelivedIntangibleAssetsAccumulatedAmortizationRollForward_0b057ed8-5658-431b-bff5-85e985353c39" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationAbstract_87ed545c-6a9d-4d1c-8ec6-89bbcf98a4fe" xlink:href="pbh-20250630.xsd#pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_FinitelivedIntangibleAssetsAccumulatedAmortizationRollForward_0b057ed8-5658-431b-bff5-85e985353c39" xlink:to="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationAbstract_87ed545c-6a9d-4d1c-8ec6-89bbcf98a4fe" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_62075992-1049-4cbe-8f9f-38844313d0fd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationAbstract_87ed545c-6a9d-4d1c-8ec6-89bbcf98a4fe" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_62075992-1049-4cbe-8f9f-38844313d0fd" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_34171667-018b-45ef-95a9-e03d6bdad619" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationAbstract_87ed545c-6a9d-4d1c-8ec6-89bbcf98a4fe" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_34171667-018b-45ef-95a9-e03d6bdad619" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationTranslationAdjustmentsGainLoss_296df93e-fa14-49b5-9ab0-3316b349e329" xlink:href="pbh-20250630.xsd#pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationTranslationAdjustmentsGainLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationAbstract_87ed545c-6a9d-4d1c-8ec6-89bbcf98a4fe" xlink:to="loc_pbh_FiniteLivedIntangibleAssetsAccumulatedAmortizationTranslationAdjustmentsGainLoss_296df93e-fa14-49b5-9ab0-3316b349e329" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_ebf3ad3f-e193-49df-aaf1-28d6b8e84e76" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNetAbstract_e44d3091-a7d1-45d0-9e39-65a1430f560c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNetAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNetAbstract_e44d3091-a7d1-45d0-9e39-65a1430f560c" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_4b73817b-66e7-4d86-aed6-2c6195aeaa13" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNetAbstract_e44d3091-a7d1-45d0-9e39-65a1430f560c" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsNet_4b73817b-66e7-4d86-aed6-2c6195aeaa13" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwillAbstract_74223b5a-7e27-422d-a07f-da9174626798" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwillAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_pbh_ScheduleOfIntangibleAssetsLineItems_88cc47aa-b8f8-4dc8-88be-faf4717029b9" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwillAbstract_74223b5a-7e27-422d-a07f-da9174626798" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_2aea453c-fbbc-4096-9c1e-10ab6825ea05" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwillAbstract_74223b5a-7e27-422d-a07f-da9174626798" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_2aea453c-fbbc-4096-9c1e-10ab6825ea05" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/IntangibleAssetsnetNarrativeDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#IntangibleAssetsnetNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/IntangibleAssetsnetNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_8feba575-e780-48d5-ba9e-6d2b695a3f45" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_20f9ddd7-7ccd-4107-9bf1-9045a4968594" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_8feba575-e780-48d5-ba9e-6d2b695a3f45" xlink:to="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_20f9ddd7-7ccd-4107-9bf1-9045a4968594" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_3c5b0d41-84f2-48bb-9b61-1f085f6180dc" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfFiniteLivedIntangibleAssetsTable_20f9ddd7-7ccd-4107-9bf1-9045a4968594" xlink:to="loc_srt_RangeAxis_3c5b0d41-84f2-48bb-9b61-1f085f6180dc" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_3c5b0d41-84f2-48bb-9b61-1f085f6180dc_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_3c5b0d41-84f2-48bb-9b61-1f085f6180dc" xlink:to="loc_srt_RangeMember_3c5b0d41-84f2-48bb-9b61-1f085f6180dc_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_9dc8e038-5ff0-422e-99f8-95120f52a7e9" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_3c5b0d41-84f2-48bb-9b61-1f085f6180dc" xlink:to="loc_srt_RangeMember_9dc8e038-5ff0-422e-99f8-95120f52a7e9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_e60ad14c-12bc-4357-be4b-7f9b212ccd79" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MinimumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_9dc8e038-5ff0-422e-99f8-95120f52a7e9" xlink:to="loc_srt_MinimumMember_e60ad14c-12bc-4357-be4b-7f9b212ccd79" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_551ae6d7-81ac-4021-a716-e34c371b95f0" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MaximumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_9dc8e038-5ff0-422e-99f8-95120f52a7e9" xlink:to="loc_srt_MaximumMember_551ae6d7-81ac-4021-a716-e34c371b95f0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_a26f70e5-0b57-4fe1-ac9c-9ac7726ae044" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AmortizationOfIntangibleAssets"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_8feba575-e780-48d5-ba9e-6d2b695a3f45" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_a26f70e5-0b57-4fe1-ac9c-9ac7726ae044" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_e0a5356d-e23c-4f71-ba24-52bf658a3181" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsLineItems_8feba575-e780-48d5-ba9e-6d2b695a3f45" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_e0a5356d-e23c-4f71-ba24-52bf658a3181" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/LongTermDebtScheduleofLongtermDebtDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#LongTermDebtScheduleofLongtermDebtDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/LongTermDebtScheduleofLongtermDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_c3865c56-f00b-4bec-b374-6809e1c3ee71" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_f41b08a1-ced5-471c-ba00-c1a3f36b4191" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_c3865c56-f00b-4bec-b374-6809e1c3ee71" xlink:to="loc_us-gaap_DebtInstrumentTable_f41b08a1-ced5-471c-ba00-c1a3f36b4191" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_47ab7cd6-6f5b-400a-be53-2c70af07cc28" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_f41b08a1-ced5-471c-ba00-c1a3f36b4191" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_47ab7cd6-6f5b-400a-be53-2c70af07cc28" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_47ab7cd6-6f5b-400a-be53-2c70af07cc28_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_47ab7cd6-6f5b-400a-be53-2c70af07cc28" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_47ab7cd6-6f5b-400a-be53-2c70af07cc28_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_e11ce4da-1c2d-42d3-be23-585d6b8d9a00" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_47ab7cd6-6f5b-400a-be53-2c70af07cc28" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_e11ce4da-1c2d-42d3-be23-585d6b8d9a00" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_7d94324a-2620-44ce-9246-308eb27aa5be" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SeniorNotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_e11ce4da-1c2d-42d3-be23-585d6b8d9a00" xlink:to="loc_us-gaap_SeniorNotesMember_7d94324a-2620-44ce-9246-308eb27aa5be" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_c1e5b691-7c72-4ddd-99fb-44bcff447e84" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_f41b08a1-ced5-471c-ba00-c1a3f36b4191" xlink:to="loc_us-gaap_DebtInstrumentAxis_c1e5b691-7c72-4ddd-99fb-44bcff447e84" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_c1e5b691-7c72-4ddd-99fb-44bcff447e84_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_c1e5b691-7c72-4ddd-99fb-44bcff447e84" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_c1e5b691-7c72-4ddd-99fb-44bcff447e84_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_be25b6e8-af57-481f-9802-7022a7369231" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_c1e5b691-7c72-4ddd-99fb-44bcff447e84" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_be25b6e8-af57-481f-9802-7022a7369231" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_A2021SeniorNotesMember_91d4cff2-72c4-4fd8-b24f-e6d04fdb88c2" xlink:href="pbh-20250630.xsd#pbh_A2021SeniorNotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_be25b6e8-af57-481f-9802-7022a7369231" xlink:to="loc_pbh_A2021SeniorNotesMember_91d4cff2-72c4-4fd8-b24f-e6d04fdb88c2" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_A2019SeniorNotesMember_5435f4f5-1ad6-4870-adbd-e7130a5ae61f" xlink:href="pbh-20250630.xsd#pbh_A2019SeniorNotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_be25b6e8-af57-481f-9802-7022a7369231" xlink:to="loc_pbh_A2019SeniorNotesMember_5435f4f5-1ad6-4870-adbd-e7130a5ae61f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_63e9450a-2afa-426f-9fde-a69a18ead961" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_c3865c56-f00b-4bec-b374-6809e1c3ee71" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_63e9450a-2afa-426f-9fde-a69a18ead961" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_f7457962-1d67-425e-9648-f213c6612e0b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_c3865c56-f00b-4bec-b374-6809e1c3ee71" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_f7457962-1d67-425e-9648-f213c6612e0b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_9e080623-671b-4070-93dd-174134036fbd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_c3865c56-f00b-4bec-b374-6809e1c3ee71" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet_9e080623-671b-4070-93dd-174134036fbd" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_2f8fb45b-9717-4f86-b910-965984ab05fb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebt"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_c3865c56-f00b-4bec-b374-6809e1c3ee71" xlink:to="loc_us-gaap_LongTermDebt_2f8fb45b-9717-4f86-b910-965984ab05fb" xlink:type="arc" order="3"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/LongTermDebtNarrativeDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#LongTermDebtNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/LongTermDebtNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_7a75e823-5241-4186-ac33-b8914f5a1ae2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_d297f2c4-12f4-4553-bacd-815a24d21a3d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7a75e823-5241-4186-ac33-b8914f5a1ae2" xlink:to="loc_us-gaap_DebtInstrumentTable_d297f2c4-12f4-4553-bacd-815a24d21a3d" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_85f34c9f-4769-4ccc-bc44-539e663be768" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CreditFacilityAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_d297f2c4-12f4-4553-bacd-815a24d21a3d" xlink:to="loc_us-gaap_CreditFacilityAxis_85f34c9f-4769-4ccc-bc44-539e663be768" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_85f34c9f-4769-4ccc-bc44-539e663be768_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CreditFacilityDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_CreditFacilityAxis_85f34c9f-4769-4ccc-bc44-539e663be768" xlink:to="loc_us-gaap_CreditFacilityDomain_85f34c9f-4769-4ccc-bc44-539e663be768_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_e026fedc-f538-449a-8474-45dbfdb51707" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CreditFacilityDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_CreditFacilityAxis_85f34c9f-4769-4ccc-bc44-539e663be768" xlink:to="loc_us-gaap_CreditFacilityDomain_e026fedc-f538-449a-8474-45dbfdb51707" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevolvingCreditFacilityMember_220a813c-3153-463f-9fcd-10f435ce958f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevolvingCreditFacilityMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_CreditFacilityDomain_e026fedc-f538-449a-8474-45dbfdb51707" xlink:to="loc_us-gaap_RevolvingCreditFacilityMember_220a813c-3153-463f-9fcd-10f435ce958f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_54cb709b-4eaa-471a-9d55-f5182d70bac5" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_DebtInstrumentTable_d297f2c4-12f4-4553-bacd-815a24d21a3d" xlink:to="loc_us-gaap_DebtInstrumentAxis_54cb709b-4eaa-471a-9d55-f5182d70bac5" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_54cb709b-4eaa-471a-9d55-f5182d70bac5_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_54cb709b-4eaa-471a-9d55-f5182d70bac5" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_54cb709b-4eaa-471a-9d55-f5182d70bac5_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_f63b66f2-7c5c-441b-a6b9-ac28fc4f3060" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_54cb709b-4eaa-471a-9d55-f5182d70bac5" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_f63b66f2-7c5c-441b-a6b9-ac28fc4f3060" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_A2012ABLRevolverMember_4a6c831b-dc74-4407-95e5-60ba1ed4f231" xlink:href="pbh-20250630.xsd#pbh_A2012ABLRevolverMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_f63b66f2-7c5c-441b-a6b9-ac28fc4f3060" xlink:to="loc_pbh_A2012ABLRevolverMember_4a6c831b-dc74-4407-95e5-60ba1ed4f231" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_da826485-ea6d-46f0-bd44-9b99b30be6ff" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7a75e823-5241-4186-ac33-b8914f5a1ae2" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_da826485-ea6d-46f0-bd44-9b99b30be6ff" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCredit_0b4c93a5-24af-46ec-acda-ec4dbb191bb1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LineOfCredit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7a75e823-5241-4186-ac33-b8914f5a1ae2" xlink:to="loc_us-gaap_LineOfCredit_0b4c93a5-24af-46ec-acda-ec4dbb191bb1" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/FairValueMeasurementsDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#FairValueMeasurementsDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/FairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_ccbf2692-f842-4ade-bdf0-d8bca8d81cfa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByBalanceSheetGroupingTable_cb5ea00e-6b8d-43df-ae3f-4f8469e5db3c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByBalanceSheetGroupingTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_ccbf2692-f842-4ade-bdf0-d8bca8d81cfa" xlink:to="loc_us-gaap_FairValueByBalanceSheetGroupingTable_cb5ea00e-6b8d-43df-ae3f-4f8469e5db3c" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_24c4838c-fd9d-45de-889f-f0396aa5b943" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_cb5ea00e-6b8d-43df-ae3f-4f8469e5db3c" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_24c4838c-fd9d-45de-889f-f0396aa5b943" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_24c4838c-fd9d-45de-889f-f0396aa5b943_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_24c4838c-fd9d-45de-889f-f0396aa5b943" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_24c4838c-fd9d-45de-889f-f0396aa5b943_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_35081945-1e3d-4861-aa47-acaa3464642a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_24c4838c-fd9d-45de-889f-f0396aa5b943" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_35081945-1e3d-4861-aa47-acaa3464642a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeniorNotesMember_02bdbc0f-2f75-4947-9c25-4c2f3d63bb22" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SeniorNotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_35081945-1e3d-4861-aa47-acaa3464642a" xlink:to="loc_us-gaap_SeniorNotesMember_02bdbc0f-2f75-4947-9c25-4c2f3d63bb22" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_33e2be2f-b35b-4757-85c6-d15c9ad79bbb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_cb5ea00e-6b8d-43df-ae3f-4f8469e5db3c" xlink:to="loc_us-gaap_DebtInstrumentAxis_33e2be2f-b35b-4757-85c6-d15c9ad79bbb" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_33e2be2f-b35b-4757-85c6-d15c9ad79bbb_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_DebtInstrumentAxis_33e2be2f-b35b-4757-85c6-d15c9ad79bbb" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_33e2be2f-b35b-4757-85c6-d15c9ad79bbb_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_96eae536-905d-4a94-a87c-8dfd11bb54e0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_DebtInstrumentAxis_33e2be2f-b35b-4757-85c6-d15c9ad79bbb" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_96eae536-905d-4a94-a87c-8dfd11bb54e0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_A2019SeniorNotesMember_59e1f724-040a-4492-8c42-6ffaa74093d3" xlink:href="pbh-20250630.xsd#pbh_A2019SeniorNotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_96eae536-905d-4a94-a87c-8dfd11bb54e0" xlink:to="loc_pbh_A2019SeniorNotesMember_59e1f724-040a-4492-8c42-6ffaa74093d3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_A2021SeniorNotesMember_7fe0274a-1c01-423a-8f2b-dc44478a4f72" xlink:href="pbh-20250630.xsd#pbh_A2021SeniorNotesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_96eae536-905d-4a94-a87c-8dfd11bb54e0" xlink:to="loc_pbh_A2021SeniorNotesMember_7fe0274a-1c01-423a-8f2b-dc44478a4f72" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementBasisAxis_12ac37c3-d105-44be-adaa-7373779de267" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByMeasurementBasisAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_cb5ea00e-6b8d-43df-ae3f-4f8469e5db3c" xlink:to="loc_us-gaap_FairValueByMeasurementBasisAxis_12ac37c3-d105-44be-adaa-7373779de267" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_12ac37c3-d105-44be-adaa-7373779de267_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PortionAtFairValueFairValueDisclosureMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByMeasurementBasisAxis_12ac37c3-d105-44be-adaa-7373779de267" xlink:to="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_12ac37c3-d105-44be-adaa-7373779de267_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosureItemAmountsDomain_3bc43cc6-749c-40c7-bb19-84699a7d3694" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueDisclosureItemAmountsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByMeasurementBasisAxis_12ac37c3-d105-44be-adaa-7373779de267" xlink:to="loc_us-gaap_FairValueDisclosureItemAmountsDomain_3bc43cc6-749c-40c7-bb19-84699a7d3694" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_7bc9afcb-92de-42a7-bb2a-42cd13036d0c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PortionAtFairValueFairValueDisclosureMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueDisclosureItemAmountsDomain_3bc43cc6-749c-40c7-bb19-84699a7d3694" xlink:to="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_7bc9afcb-92de-42a7-bb2a-42cd13036d0c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CarryingReportedAmountFairValueDisclosureMember_3c54269a-5419-44f3-a51c-3a4a29d21b61" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CarryingReportedAmountFairValueDisclosureMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_7bc9afcb-92de-42a7-bb2a-42cd13036d0c" xlink:to="loc_us-gaap_CarryingReportedAmountFairValueDisclosureMember_3c54269a-5419-44f3-a51c-3a4a29d21b61" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EstimateOfFairValueFairValueDisclosureMember_e30065cf-a857-4ce9-b9c1-a368c3d22eec" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EstimateOfFairValueFairValueDisclosureMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PortionAtFairValueFairValueDisclosureMember_7bc9afcb-92de-42a7-bb2a-42cd13036d0c" xlink:to="loc_us-gaap_EstimateOfFairValueFairValueDisclosureMember_e30065cf-a857-4ce9-b9c1-a368c3d22eec" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_2bfbd1a7-0577-4885-ab04-05a58273da1f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_cb5ea00e-6b8d-43df-ae3f-4f8469e5db3c" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_2bfbd1a7-0577-4885-ab04-05a58273da1f" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2bfbd1a7-0577-4885-ab04-05a58273da1f_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_2bfbd1a7-0577-4885-ab04-05a58273da1f" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_2bfbd1a7-0577-4885-ab04-05a58273da1f_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_94713f03-a502-431e-a52a-83d8c9d5b90b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_2bfbd1a7-0577-4885-ab04-05a58273da1f" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_94713f03-a502-431e-a52a-83d8c9d5b90b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_8afe8d25-e524-4e83-a93b-e390a447764a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_94713f03-a502-431e-a52a-83d8c9d5b90b" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_8afe8d25-e524-4e83-a93b-e390a447764a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtFairValue_7706e4e8-12e2-4b0b-9425-f76a5f1865d2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_LongTermDebtFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_ccbf2692-f842-4ade-bdf0-d8bca8d81cfa" xlink:to="loc_us-gaap_LongTermDebtFairValue_7706e4e8-12e2-4b0b-9425-f76a5f1865d2" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/StockholdersEquityScheduleofRepurchasedSharesDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#StockholdersEquityScheduleofRepurchasedSharesDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/StockholdersEquityScheduleofRepurchasedSharesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_5014ed57-dcaa-4a50-bf2e-583fd9a3eb5b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_dba0d0d0-5ea6-41ef-8d20-024626d195b3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ClassOfStockLineItems_5014ed57-dcaa-4a50-bf2e-583fd9a3eb5b" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_dba0d0d0-5ea6-41ef-8d20-024626d195b3" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_252a3802-2d79-4a27-bbc1-9abf6b52a7fa" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_dba0d0d0-5ea6-41ef-8d20-024626d195b3" xlink:to="loc_us-gaap_AwardTypeAxis_252a3802-2d79-4a27-bbc1-9abf6b52a7fa" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_252a3802-2d79-4a27-bbc1-9abf6b52a7fa_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_252a3802-2d79-4a27-bbc1-9abf6b52a7fa" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_252a3802-2d79-4a27-bbc1-9abf6b52a7fa_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0e336a62-ddb6-4e9c-aa03-4be6b474bdaf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_252a3802-2d79-4a27-bbc1-9abf6b52a7fa" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0e336a62-ddb6-4e9c-aa03-4be6b474bdaf" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_066102c6-6482-46d6-b546-3e51b449979f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_0e336a62-ddb6-4e9c-aa03-4be6b474bdaf" xlink:to="loc_us-gaap_RestrictedStockMember_066102c6-6482-46d6-b546-3e51b449979f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ShareRepurchaseProgramAxis_ded957a6-b76f-4d2b-b789-07389e3cc4a3" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ShareRepurchaseProgramAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_dba0d0d0-5ea6-41ef-8d20-024626d195b3" xlink:to="loc_srt_ShareRepurchaseProgramAxis_ded957a6-b76f-4d2b-b789-07389e3cc4a3" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ShareRepurchaseProgramDomain_ded957a6-b76f-4d2b-b789-07389e3cc4a3_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ShareRepurchaseProgramDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ShareRepurchaseProgramAxis_ded957a6-b76f-4d2b-b789-07389e3cc4a3" xlink:to="loc_srt_ShareRepurchaseProgramDomain_ded957a6-b76f-4d2b-b789-07389e3cc4a3_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ShareRepurchaseProgramDomain_5c20380b-a46e-4fa9-b20b-748c51b02574" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ShareRepurchaseProgramDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ShareRepurchaseProgramAxis_ded957a6-b76f-4d2b-b789-07389e3cc4a3" xlink:to="loc_srt_ShareRepurchaseProgramDomain_5c20380b-a46e-4fa9-b20b-748c51b02574" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ShareRepurchaseProgramMember_ade62779-b75c-4d0c-ad2b-dad34b95e912" xlink:href="pbh-20250630.xsd#pbh_ShareRepurchaseProgramMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ShareRepurchaseProgramDomain_5c20380b-a46e-4fa9-b20b-748c51b02574" xlink:to="loc_pbh_ShareRepurchaseProgramMember_ade62779-b75c-4d0c-ad2b-dad34b95e912" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockSharesAcquired_cc4bef89-46f1-40c6-9ae4-cb8d0c712d74" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockSharesAcquired"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_5014ed57-dcaa-4a50-bf2e-583fd9a3eb5b" xlink:to="loc_us-gaap_TreasuryStockSharesAcquired_cc4bef89-46f1-40c6-9ae4-cb8d0c712d74" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare_6388eb73-c1e1-4c82-985f-04b95df5e49e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockAcquiredAverageCostPerShare"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_5014ed57-dcaa-4a50-bf2e-583fd9a3eb5b" xlink:to="loc_us-gaap_TreasuryStockAcquiredAverageCostPerShare_6388eb73-c1e1-4c82-985f-04b95df5e49e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_d6b8c588-a36d-480e-9879-4c7df40601c3" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_TreasuryStockValueAcquiredCostMethod"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockLineItems_5014ed57-dcaa-4a50-bf2e-583fd9a3eb5b" xlink:to="loc_us-gaap_TreasuryStockValueAcquiredCostMethod_d6b8c588-a36d-480e-9879-4c7df40601c3" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/AccumulatedOtherComprehensiveLossScheduleofComponentsofAOCLDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#AccumulatedOtherComprehensiveLossScheduleofComponentsofAOCLDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/AccumulatedOtherComprehensiveLossScheduleofComponentsofAOCLDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_13731e47-21b6-4051-93f6-a4aa56d2346e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_789e9988-0914-4028-8b87-8ac7634abda2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_13731e47-21b6-4051-93f6-a4aa56d2346e" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_789e9988-0914-4028-8b87-8ac7634abda2" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_8e61085f-2389-4af2-8bcb-bf09cd43bfa4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossTable_789e9988-0914-4028-8b87-8ac7634abda2" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_8e61085f-2389-4af2-8bcb-bf09cd43bfa4" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_8e61085f-2389-4af2-8bcb-bf09cd43bfa4_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_8e61085f-2389-4af2-8bcb-bf09cd43bfa4" xlink:to="loc_us-gaap_EquityComponentDomain_8e61085f-2389-4af2-8bcb-bf09cd43bfa4_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_7c00944b-a845-4911-9dbe-cdc799df4d61" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EquityComponentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_8e61085f-2389-4af2-8bcb-bf09cd43bfa4" xlink:to="loc_us-gaap_EquityComponentDomain_7c00944b-a845-4911-9dbe-cdc799df4d61" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_16e89660-3be1-4c1b-bbdc-661ab36cb2c6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EquityComponentDomain_7c00944b-a845-4911-9dbe-cdc799df4d61" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_16e89660-3be1-4c1b-bbdc-661ab36cb2c6" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedTranslationAdjustmentMember_643dd1ba-9139-4697-adc6-639b89b336f1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedTranslationAdjustmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_16e89660-3be1-4c1b-bbdc-661ab36cb2c6" xlink:to="loc_us-gaap_AccumulatedTranslationAdjustmentMember_643dd1ba-9139-4697-adc6-639b89b336f1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_079d459c-b4f6-4091-9a12-74988e286706" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_16e89660-3be1-4c1b-bbdc-661ab36cb2c6" xlink:to="loc_us-gaap_AccumulatedDefinedBenefitPlansAdjustmentMember_079d459c-b4f6-4091-9a12-74988e286706" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AociTaxAttributableToParent_12e67fc3-dd97-484b-b1f9-bcf4f6f185cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AociTaxAttributableToParent"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_13731e47-21b6-4051-93f6-a4aa56d2346e" xlink:to="loc_us-gaap_AociTaxAttributableToParent_12e67fc3-dd97-484b-b1f9-bcf4f6f185cb" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_889add47-d70a-4bc5-ad88-582e251caa4f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockholdersEquity"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossLineItems_13731e47-21b6-4051-93f6-a4aa56d2346e" xlink:to="loc_us-gaap_StockholdersEquity_889add47-d70a-4bc5-ad88-582e251caa4f" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/EarningsPerShareAntidilutiveSecuritiesNarrativeDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#EarningsPerShareAntidilutiveSecuritiesNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/EarningsPerShareAntidilutiveSecuritiesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_a1ac483a-2210-4dbe-b680-10f455e70d25" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_63a7d0a6-e59c-42db-8f0f-c2f65eeb4aad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_a1ac483a-2210-4dbe-b680-10f455e70d25" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_63a7d0a6-e59c-42db-8f0f-c2f65eeb4aad" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_e4b44dc3-7a5b-4e3c-9000-9c5bfc183807" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_63a7d0a6-e59c-42db-8f0f-c2f65eeb4aad" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_e4b44dc3-7a5b-4e3c-9000-9c5bfc183807" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e4b44dc3-7a5b-4e3c-9000-9c5bfc183807_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_e4b44dc3-7a5b-4e3c-9000-9c5bfc183807" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e4b44dc3-7a5b-4e3c-9000-9c5bfc183807_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_81fc944e-0b09-43cd-bf93-982fca0d0aed" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_e4b44dc3-7a5b-4e3c-9000-9c5bfc183807" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_81fc944e-0b09-43cd-bf93-982fca0d0aed" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockCompensationPlanMember_19efef11-1629-4a70-a693-689487746b88" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StockCompensationPlanMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_81fc944e-0b09-43cd-bf93-982fca0d0aed" xlink:to="loc_us-gaap_StockCompensationPlanMember_19efef11-1629-4a70-a693-689487746b88" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_018c3143-1faf-4d2f-bd39-440d41cb19f6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_a1ac483a-2210-4dbe-b680-10f455e70d25" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_018c3143-1faf-4d2f-bd39-440d41cb19f6" xlink:type="arc" order="0"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/StockBasedCompensationNarrativeDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#StockBasedCompensationNarrativeDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/StockBasedCompensationNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_484bed3d-99ec-4064-a22f-0960c747727b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_484bed3d-99ec-4064-a22f-0960c747727b" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_7146fc2c-df10-460c-944f-874398e4618e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PlanNameAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_484bed3d-99ec-4064-a22f-0960c747727b" xlink:to="loc_us-gaap_PlanNameAxis_7146fc2c-df10-460c-944f-874398e4618e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_7146fc2c-df10-460c-944f-874398e4618e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_PlanNameAxis_7146fc2c-df10-460c-944f-874398e4618e" xlink:to="loc_us-gaap_PlanNameDomain_7146fc2c-df10-460c-944f-874398e4618e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_94bcb821-cb7d-408d-a814-68c8be4a4c13" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_PlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_PlanNameAxis_7146fc2c-df10-460c-944f-874398e4618e" xlink:to="loc_us-gaap_PlanNameDomain_94bcb821-cb7d-408d-a814-68c8be4a4c13" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_LongtermEquityIncentivePlan2005Member_82ec9469-875a-40b7-89c5-379e705fd45e" xlink:href="pbh-20250630.xsd#pbh_LongtermEquityIncentivePlan2005Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanNameDomain_94bcb821-cb7d-408d-a814-68c8be4a4c13" xlink:to="loc_pbh_LongtermEquityIncentivePlan2005Member_82ec9469-875a-40b7-89c5-379e705fd45e" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_LongTermIncentivePlan2020Member_7ddd542c-67e6-4358-8388-de8e2ea27bd9" xlink:href="pbh-20250630.xsd#pbh_LongTermIncentivePlan2020Member"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_PlanNameDomain_94bcb821-cb7d-408d-a814-68c8be4a4c13" xlink:to="loc_pbh_LongTermIncentivePlan2020Member_7ddd542c-67e6-4358-8388-de8e2ea27bd9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_477e5dd6-1e07-49b0-b75e-8289ea442986" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_484bed3d-99ec-4064-a22f-0960c747727b" xlink:to="loc_us-gaap_AwardTypeAxis_477e5dd6-1e07-49b0-b75e-8289ea442986" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_477e5dd6-1e07-49b0-b75e-8289ea442986_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_477e5dd6-1e07-49b0-b75e-8289ea442986" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_477e5dd6-1e07-49b0-b75e-8289ea442986_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6542fa3c-65ed-41c8-baf4-1893803d5073" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_477e5dd6-1e07-49b0-b75e-8289ea442986" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6542fa3c-65ed-41c8-baf4-1893803d5073" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_47485e46-60ec-400e-93de-c5bd36a6e882" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6542fa3c-65ed-41c8-baf4-1893803d5073" xlink:to="loc_us-gaap_EmployeeStockOptionMember_47485e46-60ec-400e-93de-c5bd36a6e882" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_RestrictedStockUnitsRSUsPerformanceStockUnitsPSUsMember_2d11a2d1-25ff-4b7c-89b3-993aff9acebf" xlink:href="pbh-20250630.xsd#pbh_RestrictedStockUnitsRSUsPerformanceStockUnitsPSUsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_6542fa3c-65ed-41c8-baf4-1893803d5073" xlink:to="loc_pbh_RestrictedStockUnitsRSUsPerformanceStockUnitsPSUsMember_2d11a2d1-25ff-4b7c-89b3-993aff9acebf" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_d27b649f-4cff-44a8-9bb8-cdd180d13027" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_d27b649f-4cff-44a8-9bb8-cdd180d13027" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_24066d8e-2a30-4f40-8b96-6a6dfa7ff847" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfAdditionalSharesAuthorized_24066d8e-2a30-4f40-8b96-6a6dfa7ff847" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_6d23ac9b-60f2-43e9-aedb-b3168d606544" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_6d23ac9b-60f2-43e9-aedb-b3168d606544" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_CommonStockCapitalSharesReservedForFutureIssuanceNewShares_754799ec-c8e1-4033-86de-0f6bf2baf42d" xlink:href="pbh-20250630.xsd#pbh_CommonStockCapitalSharesReservedForFutureIssuanceNewShares"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_pbh_CommonStockCapitalSharesReservedForFutureIssuanceNewShares_754799ec-c8e1-4033-86de-0f6bf2baf42d" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_CommonStockCapitalSharesReservedForFutureIssuanceUnissuedShares_b664bfb4-23b9-478d-890c-15098eb38c62" xlink:href="pbh-20250630.xsd#pbh_CommonStockCapitalSharesReservedForFutureIssuanceUnissuedShares"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_pbh_CommonStockCapitalSharesReservedForFutureIssuanceUnissuedShares_b664bfb4-23b9-478d-890c-15098eb38c62" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_dedc8ab5-59ad-45a3-85ff-beab550c4bf4" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_dedc8ab5-59ad-45a3-85ff-beab550c4bf4" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_6f41c2c5-bfe4-429c-90ef-5c963d8ef4cc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions_6f41c2c5-bfe4-429c-90ef-5c963d8ef4cc" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_7ea7c482-5bdb-4e4f-be96-42e6395da22e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_7ea7c482-5bdb-4e4f-be96-42e6395da22e" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_aae8ab15-8c6e-4ef6-a4c2-057195f3bd03" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedShareBasedAwardsOtherThanOptions_aae8ab15-8c6e-4ef6-a4c2-057195f3bd03" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_b73a6dd2-0fb7-4420-9db4-d93c4d592315" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ccb9f77d-0068-4f1a-8ac7-0457bd0562f2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue_b73a6dd2-0fb7-4420-9db4-d93c4d592315" xlink:type="arc" order="9"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/StockBasedCompensationScheduleofRestrictedStockUnitsActivityDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#StockBasedCompensationScheduleofRestrictedStockUnitsActivityDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/StockBasedCompensationScheduleofRestrictedStockUnitsActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ec9c79df-10a0-422e-b1d5-76abce4d317e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c27a4bdc-31ae-4a46-ab65-4c6add96374d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ec9c79df-10a0-422e-b1d5-76abce4d317e" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c27a4bdc-31ae-4a46-ab65-4c6add96374d" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_1d6aa39b-44fe-4e48-904b-10c158a318ae" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_c27a4bdc-31ae-4a46-ab65-4c6add96374d" xlink:to="loc_us-gaap_AwardTypeAxis_1d6aa39b-44fe-4e48-904b-10c158a318ae" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1d6aa39b-44fe-4e48-904b-10c158a318ae_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_1d6aa39b-44fe-4e48-904b-10c158a318ae" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1d6aa39b-44fe-4e48-904b-10c158a318ae_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_84476653-42c9-4f30-b259-a61ebe71e510" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_1d6aa39b-44fe-4e48-904b-10c158a318ae" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_84476653-42c9-4f30-b259-a61ebe71e510" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_2b72a79e-ab31-43d7-8530-b5731be54424" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_84476653-42c9-4f30-b259-a61ebe71e510" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_2b72a79e-ab31-43d7-8530-b5731be54424" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ec9c79df-10a0-422e-b1d5-76abce4d317e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_559d838b-d376-4cd8-9772-cbd3accb2ffd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_559d838b-d376-4cd8-9772-cbd3accb2ffd" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_62651555-2d39-44c8-97cd-60992963972b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_62651555-2d39-44c8-97cd-60992963972b" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIncrementalPerformanceShares_285a3aa2-099b-4111-878b-75db9448a933" xlink:href="pbh-20250630.xsd#pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIncrementalPerformanceShares"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:to="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsIncrementalPerformanceShares_285a3aa2-099b-4111-878b-75db9448a933" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndIssued_51839fe0-8bbe-464f-81f8-f5724fa7053d" xlink:href="pbh-20250630.xsd#pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndIssued"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:to="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndIssued_51839fe0-8bbe-464f-81f8-f5724fa7053d" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_1685289a-eec7-4677-af1a-6757132108f9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_d8d4e507-44c5-4eea-aac4-701f875c6319" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_1685289a-eec7-4677-af1a-6757132108f9" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber_ce912aa9-3ecc-4fb7-8bbc-ed5b395f9deb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingNumber"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedNumber_49b8bce2-a28d-4545-8bf7-d6601fa31232" xlink:href="pbh-20250630.xsd#pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ec9c79df-10a0-422e-b1d5-76abce4d317e" xlink:to="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedNumber_49b8bce2-a28d-4545-8bf7-d6601fa31232" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2cc5757c-7b20-437c-8060-5870134f5135" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ec9c79df-10a0-422e-b1d5-76abce4d317e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2cc5757c-7b20-437c-8060-5870134f5135" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_e4a4fee4-36ff-4610-b985-f3d15d51f7dc" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2cc5757c-7b20-437c-8060-5870134f5135" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_e4a4fee4-36ff-4610-b985-f3d15d51f7dc" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_abd345b2-2bc6-41af-ad20-cbf178c80374" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2cc5757c-7b20-437c-8060-5870134f5135" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_abd345b2-2bc6-41af-ad20-cbf178c80374" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndIssuedInPeriodWeightedAverageGrantDateFairValue_fae4cda5-c0da-47e2-8373-52e00b0ec37d" xlink:href="pbh-20250630.xsd#pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndIssuedInPeriodWeightedAverageGrantDateFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2cc5757c-7b20-437c-8060-5870134f5135" xlink:to="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedAndIssuedInPeriodWeightedAverageGrantDateFairValue_fae4cda5-c0da-47e2-8373-52e00b0ec37d" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_e4cafcfd-ef9b-4359-be5a-1d081fba693a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_2cc5757c-7b20-437c-8060-5870134f5135" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_e4cafcfd-ef9b-4359-be5a-1d081fba693a" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_5c4a87e5-1b99-490e-bf92-0a051a263f9b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedWeightedAverageGrantDateFairValue_5492dbc4-2c72-45e6-a1af-17db7aab9bfa" xlink:href="pbh-20250630.xsd#pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedWeightedAverageGrantDateFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_ec9c79df-10a0-422e-b1d5-76abce4d317e" xlink:to="loc_pbh_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedWeightedAverageGrantDateFairValue_5492dbc4-2c72-45e6-a1af-17db7aab9bfa" xlink:type="arc" order="3"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/StockBasedCompensationScheduleofStockOptionValuationAssumptionsDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#StockBasedCompensationScheduleofStockOptionValuationAssumptionsDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/StockBasedCompensationScheduleofStockOptionValuationAssumptionsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ec56db04-6002-44a2-9006-a3235392a3b2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ec56db04-6002-44a2-9006-a3235392a3b2" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_c149eb2f-68a1-4b63-a9cd-ac7c3feb7a9c" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ec56db04-6002-44a2-9006-a3235392a3b2" xlink:to="loc_srt_RangeAxis_c149eb2f-68a1-4b63-a9cd-ac7c3feb7a9c" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_c149eb2f-68a1-4b63-a9cd-ac7c3feb7a9c_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_RangeAxis_c149eb2f-68a1-4b63-a9cd-ac7c3feb7a9c" xlink:to="loc_srt_RangeMember_c149eb2f-68a1-4b63-a9cd-ac7c3feb7a9c_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_0be23faf-681c-4b25-9a1c-22c228674059" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_RangeMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_RangeAxis_c149eb2f-68a1-4b63-a9cd-ac7c3feb7a9c" xlink:to="loc_srt_RangeMember_0be23faf-681c-4b25-9a1c-22c228674059" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_8d6b9ab1-494b-4c77-8eb4-6cf25609261c" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MinimumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_0be23faf-681c-4b25-9a1c-22c228674059" xlink:to="loc_srt_MinimumMember_8d6b9ab1-494b-4c77-8eb4-6cf25609261c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_951d7fcc-817b-4a81-9355-5c3e24451567" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MaximumMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_RangeMember_0be23faf-681c-4b25-9a1c-22c228674059" xlink:to="loc_srt_MaximumMember_951d7fcc-817b-4a81-9355-5c3e24451567" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_d2345d91-9266-483d-ba46-3118dd45153d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ec56db04-6002-44a2-9006-a3235392a3b2" xlink:to="loc_us-gaap_AwardTypeAxis_d2345d91-9266-483d-ba46-3118dd45153d" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_d2345d91-9266-483d-ba46-3118dd45153d_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_d2345d91-9266-483d-ba46-3118dd45153d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_d2345d91-9266-483d-ba46-3118dd45153d_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4642a9c9-d4d7-496a-bd89-367f18ed8b35" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_d2345d91-9266-483d-ba46-3118dd45153d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4642a9c9-d4d7-496a-bd89-367f18ed8b35" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_44bed96d-9bc8-41aa-97f8-6c1a4efe9613" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_4642a9c9-d4d7-496a-bd89-367f18ed8b35" xlink:to="loc_us-gaap_EmployeeStockOptionMember_44bed96d-9bc8-41aa-97f8-6c1a4efe9613" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_e073922b-ece4-4804-a119-85a7078ad68a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_e073922b-ece4-4804-a119-85a7078ad68a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageExpectedDividend_e5e2149e-b6bd-490a-88ec-9d18e4ddfbc9" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageExpectedDividend"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageExpectedDividend_e5e2149e-b6bd-490a-88ec-9d18e4ddfbc9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_6805f2d1-855a-465f-a1da-38b66461ea52" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_6805f2d1-855a-465f-a1da-38b66461ea52" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_5018ae7a-b063-44a2-802b-7e2ed27081cb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_5018ae7a-b063-44a2-802b-7e2ed27081cb" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_e2fe1cf8-689d-4991-80dd-ebbc2ad80c6d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_15655ed4-2403-415d-bbf7-68c9aab7024b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_e2fe1cf8-689d-4991-80dd-ebbc2ad80c6d" xlink:type="arc" order="4"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/ConcentrationsofRiskDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#ConcentrationsofRiskDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/ConcentrationsofRiskDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskLineItems_35e33bab-e500-4530-ac80-97f8874d742f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTable_19de21e4-a1fb-4be5-9dcf-4afd47ff2fb8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_35e33bab-e500-4530-ac80-97f8874d742f" xlink:to="loc_us-gaap_ConcentrationRiskTable_19de21e4-a1fb-4be5-9dcf-4afd47ff2fb8" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MajorCustomersAxis_94ff1804-abfc-4d74-bac1-48a91b4036e0" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_MajorCustomersAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ConcentrationRiskTable_19de21e4-a1fb-4be5-9dcf-4afd47ff2fb8" xlink:to="loc_srt_MajorCustomersAxis_94ff1804-abfc-4d74-bac1-48a91b4036e0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_NameOfMajorCustomerDomain_94ff1804-abfc-4d74-bac1-48a91b4036e0_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_NameOfMajorCustomerDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_MajorCustomersAxis_94ff1804-abfc-4d74-bac1-48a91b4036e0" xlink:to="loc_srt_NameOfMajorCustomerDomain_94ff1804-abfc-4d74-bac1-48a91b4036e0_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_NameOfMajorCustomerDomain_b26412e8-9584-49ec-944e-7ac41569ca1b" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_NameOfMajorCustomerDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_MajorCustomersAxis_94ff1804-abfc-4d74-bac1-48a91b4036e0" xlink:to="loc_srt_NameOfMajorCustomerDomain_b26412e8-9584-49ec-944e-7ac41569ca1b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_Top5BrandsMember_c87c42af-0f51-441d-a3c2-e4eb84e49e46" xlink:href="pbh-20250630.xsd#pbh_Top5BrandsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_NameOfMajorCustomerDomain_b26412e8-9584-49ec-944e-7ac41569ca1b" xlink:to="loc_pbh_Top5BrandsMember_c87c42af-0f51-441d-a3c2-e4eb84e49e46" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_WalmartMember_6748d9c9-e6f0-490d-bc9f-c779d823302b" xlink:href="pbh-20250630.xsd#pbh_WalmartMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_NameOfMajorCustomerDomain_b26412e8-9584-49ec-944e-7ac41569ca1b" xlink:to="loc_pbh_WalmartMember_6748d9c9-e6f0-490d-bc9f-c779d823302b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_AmazonMember_f6d1b4f7-4f67-4111-ac2c-b34a994d382a" xlink:href="pbh-20250630.xsd#pbh_AmazonMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_NameOfMajorCustomerDomain_b26412e8-9584-49ec-944e-7ac41569ca1b" xlink:to="loc_pbh_AmazonMember_f6d1b4f7-4f67-4111-ac2c-b34a994d382a" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_dceb50ed-e71d-46c2-90ba-58c95fe97c16" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ConcentrationRiskTable_19de21e4-a1fb-4be5-9dcf-4afd47ff2fb8" xlink:to="loc_srt_ProductOrServiceAxis_dceb50ed-e71d-46c2-90ba-58c95fe97c16" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_dceb50ed-e71d-46c2-90ba-58c95fe97c16_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_dceb50ed-e71d-46c2-90ba-58c95fe97c16" xlink:to="loc_srt_ProductsAndServicesDomain_dceb50ed-e71d-46c2-90ba-58c95fe97c16_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_38d20a81-a4b4-4330-9c5a-a68b1396c745" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_dceb50ed-e71d-46c2-90ba-58c95fe97c16" xlink:to="loc_srt_ProductsAndServicesDomain_38d20a81-a4b4-4330-9c5a-a68b1396c745" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ManufacturesMember_ee8f59ac-53ab-40d2-867c-17eb8b261b8d" xlink:href="pbh-20250630.xsd#pbh_ManufacturesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_38d20a81-a4b4-4330-9c5a-a68b1396c745" xlink:to="loc_pbh_ManufacturesMember_ee8f59ac-53ab-40d2-867c-17eb8b261b8d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ContractPharmacalCorporationMember_87d55930-7b58-4c18-916d-1dcee0de35ea" xlink:href="pbh-20250630.xsd#pbh_ContractPharmacalCorporationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_38d20a81-a4b4-4330-9c5a-a68b1396c745" xlink:to="loc_pbh_ContractPharmacalCorporationMember_87d55930-7b58-4c18-916d-1dcee0de35ea" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_2349fe69-f327-4d83-bc1c-079526bbf24e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ConcentrationRiskTable_19de21e4-a1fb-4be5-9dcf-4afd47ff2fb8" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_2349fe69-f327-4d83-bc1c-079526bbf24e" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_2349fe69-f327-4d83-bc1c-079526bbf24e_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_2349fe69-f327-4d83-bc1c-079526bbf24e" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_2349fe69-f327-4d83-bc1c-079526bbf24e_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_b80e6c1e-ff57-43f0-afea-0c8b19fc4913" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_2349fe69-f327-4d83-bc1c-079526bbf24e" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_b80e6c1e-ff57-43f0-afea-0c8b19fc4913" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SalesMember_c76e8b4c-fa30-44a3-a9ed-22c96ca0ad7c" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SalesMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_b80e6c1e-ff57-43f0-afea-0c8b19fc4913" xlink:to="loc_us-gaap_SalesMember_c76e8b4c-fa30-44a3-a9ed-22c96ca0ad7c" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_d64f0a99-a75c-4757-9685-2f6969ce4923" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskByTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ConcentrationRiskTable_19de21e4-a1fb-4be5-9dcf-4afd47ff2fb8" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_d64f0a99-a75c-4757-9685-2f6969ce4923" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_d64f0a99-a75c-4757-9685-2f6969ce4923_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_d64f0a99-a75c-4757-9685-2f6969ce4923" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_d64f0a99-a75c-4757-9685-2f6969ce4923_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_57916611-e0cf-40f5-8c4b-33fec7c6c079" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_d64f0a99-a75c-4757-9685-2f6969ce4923" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_57916611-e0cf-40f5-8c4b-33fec7c6c079" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductConcentrationRiskMember_d2a27297-3526-4330-afdb-4323ff13cc11" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ProductConcentrationRiskMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_57916611-e0cf-40f5-8c4b-33fec7c6c079" xlink:to="loc_us-gaap_ProductConcentrationRiskMember_d2a27297-3526-4330-afdb-4323ff13cc11" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_074c2f28-ea7e-4a47-9451-332966eaca5f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CustomerConcentrationRiskMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_57916611-e0cf-40f5-8c4b-33fec7c6c079" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_074c2f28-ea7e-4a47-9451-332966eaca5f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplierConcentrationRiskMember_03bc4e19-b310-4a95-9eef-67316e689795" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SupplierConcentrationRiskMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_57916611-e0cf-40f5-8c4b-33fec7c6c079" xlink:to="loc_us-gaap_SupplierConcentrationRiskMember_03bc4e19-b310-4a95-9eef-67316e689795" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_73e0268f-81d7-4bee-a9b8-5ed72f1363ee" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ConcentrationRiskPercentage1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_35e33bab-e500-4530-ac80-97f8874d742f" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_73e0268f-81d7-4bee-a9b8-5ed72f1363ee" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_NumberOfThirdPartyManufacturers_5e6454de-455f-4c94-b6ce-96f6bd11b27a" xlink:href="pbh-20250630.xsd#pbh_NumberOfThirdPartyManufacturers"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_35e33bab-e500-4530-ac80-97f8874d742f" xlink:to="loc_pbh_NumberOfThirdPartyManufacturers_5e6454de-455f-4c94-b6ce-96f6bd11b27a" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_NumberOfThirdPartyManufacturersWithLongTermContracts_0e465e9b-832b-4787-b61e-82d85b3d9702" xlink:href="pbh-20250630.xsd#pbh_NumberOfThirdPartyManufacturersWithLongTermContracts"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ConcentrationRiskLineItems_35e33bab-e500-4530-ac80-97f8874d742f" xlink:to="loc_pbh_NumberOfThirdPartyManufacturersWithLongTermContracts_0e465e9b-832b-4787-b61e-82d85b3d9702" xlink:type="arc" order="2"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/BusinessSegmentsScheduleofInformationonOperatingandReportableSegmentsDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#BusinessSegmentsScheduleofInformationonOperatingandReportableSegmentsDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/BusinessSegmentsScheduleofInformationonOperatingandReportableSegmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationLineItems_a41d5f03-1e37-4e56-a16b-7888decf5963" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentReportingInformationLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5a2a4889-4395-4cb7-b736-359b479277a0" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_a41d5f03-1e37-4e56-a16b-7888decf5963" xlink:to="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5a2a4889-4395-4cb7-b736-359b479277a0" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsAxis_216b83f6-5b95-4708-ad7e-f02794a9ddb1" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ConsolidationItemsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5a2a4889-4395-4cb7-b736-359b479277a0" xlink:to="loc_srt_ConsolidationItemsAxis_216b83f6-5b95-4708-ad7e-f02794a9ddb1" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsDomain_216b83f6-5b95-4708-ad7e-f02794a9ddb1_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ConsolidationItemsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ConsolidationItemsAxis_216b83f6-5b95-4708-ad7e-f02794a9ddb1" xlink:to="loc_srt_ConsolidationItemsDomain_216b83f6-5b95-4708-ad7e-f02794a9ddb1_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ConsolidationItemsDomain_fb04a49d-8d13-4a0e-9091-dffe2846eec0" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ConsolidationItemsDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ConsolidationItemsAxis_216b83f6-5b95-4708-ad7e-f02794a9ddb1" xlink:to="loc_srt_ConsolidationItemsDomain_fb04a49d-8d13-4a0e-9091-dffe2846eec0" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingSegmentsMember_477c85e2-479f-4298-a643-205ee95a293d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingSegmentsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_fb04a49d-8d13-4a0e-9091-dffe2846eec0" xlink:to="loc_us-gaap_OperatingSegmentsMember_477c85e2-479f-4298-a643-205ee95a293d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntersegmentEliminationMember_d1c73282-dd3b-42aa-97b0-c1019cd89a2f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_IntersegmentEliminationMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ConsolidationItemsDomain_fb04a49d-8d13-4a0e-9091-dffe2846eec0" xlink:to="loc_us-gaap_IntersegmentEliminationMember_d1c73282-dd3b-42aa-97b0-c1019cd89a2f" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_d3cc05f6-f982-4b71-8213-555414e61564" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable_5a2a4889-4395-4cb7-b736-359b479277a0" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_d3cc05f6-f982-4b71-8213-555414e61564" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_d3cc05f6-f982-4b71-8213-555414e61564_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_d3cc05f6-f982-4b71-8213-555414e61564" xlink:to="loc_us-gaap_SegmentDomain_d3cc05f6-f982-4b71-8213-555414e61564_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_9e9e9123-9c65-4902-9a8a-4c7eff4857d6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_d3cc05f6-f982-4b71-8213-555414e61564" xlink:to="loc_us-gaap_SegmentDomain_9e9e9123-9c65-4902-9a8a-4c7eff4857d6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_NorthAmericanOTCHealthcareMember_d1784f02-c8ee-40e7-b807-e1d4c4894492" xlink:href="pbh-20250630.xsd#pbh_NorthAmericanOTCHealthcareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_9e9e9123-9c65-4902-9a8a-4c7eff4857d6" xlink:to="loc_pbh_NorthAmericanOTCHealthcareMember_d1784f02-c8ee-40e7-b807-e1d4c4894492" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_InternationalOTCHealthcareMember_38ba1e33-4eb9-4440-b971-19e0b8ead05d" xlink:href="pbh-20250630.xsd#pbh_InternationalOTCHealthcareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_9e9e9123-9c65-4902-9a8a-4c7eff4857d6" xlink:to="loc_pbh_InternationalOTCHealthcareMember_38ba1e33-4eb9-4440-b971-19e0b8ead05d" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentReportingInformationProfitLossAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationLineItems_a41d5f03-1e37-4e56-a16b-7888decf5963" xlink:to="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_49df02d3-669a-49e4-b3a8-498617f080ff" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_49df02d3-669a-49e4-b3a8-498617f080ff" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfRevenue_b6ea6c03-da22-4e8c-a808-4171f5f6f4bf" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_CostOfRevenue"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_us-gaap_CostOfRevenue_b6ea6c03-da22-4e8c-a808-4171f5f6f4bf" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_73fa8015-5244-461b-9a84-301773307215" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GrossProfit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_us-gaap_GrossProfit_73fa8015-5244-461b-9a84-301773307215" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MarketingAndAdvertisingExpense_79b42a63-7b86-45a0-9253-db105ca978bb" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_MarketingAndAdvertisingExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_us-gaap_MarketingAndAdvertisingExpense_79b42a63-7b86-45a0-9253-db105ca978bb" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_ContributionMargin_ce59d77c-5421-47cc-9a1e-1646f35111e3" xlink:href="pbh-20250630.xsd#pbh_ContributionMargin"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_pbh_ContributionMargin_ce59d77c-5421-47cc-9a1e-1646f35111e3" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_GeneralAndAdministrativeAndDepreciationAndAmortizationExpense_a7475063-667f-4b44-9b08-52a5ba6389c2" xlink:href="pbh-20250630.xsd#pbh_GeneralAndAdministrativeAndDepreciationAndAmortizationExpense"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_pbh_GeneralAndAdministrativeAndDepreciationAndAmortizationExpense_a7475063-667f-4b44-9b08-52a5ba6389c2" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_5566072c-8be9-4692-8c0b-2d9583208552" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentReportingInformationProfitLossAbstract_fe8f6dc4-1a7f-4fb5-ae19-32dd948b5e2a" xlink:to="loc_us-gaap_OperatingIncomeLoss_5566072c-8be9-4692-8c0b-2d9583208552" xlink:type="arc" order="7"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/BusinessSegmentsScheduleofRevenueDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#BusinessSegmentsScheduleofRevenueDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/BusinessSegmentsScheduleofRevenueDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_16b7f9e6-0c11-4b5e-acdd-bf1b782caf2d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_40887f75-08a1-4e71-8cc8-7b60d46ad9e2" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_16b7f9e6-0c11-4b5e-acdd-bf1b782caf2d" xlink:to="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_40887f75-08a1-4e71-8cc8-7b60d46ad9e2" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementBusinessSegmentsAxis_f07c7846-6ca3-40e9-921e-d7989c172773" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_StatementBusinessSegmentsAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_40887f75-08a1-4e71-8cc8-7b60d46ad9e2" xlink:to="loc_us-gaap_StatementBusinessSegmentsAxis_f07c7846-6ca3-40e9-921e-d7989c172773" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_f07c7846-6ca3-40e9-921e-d7989c172773_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_f07c7846-6ca3-40e9-921e-d7989c172773" xlink:to="loc_us-gaap_SegmentDomain_f07c7846-6ca3-40e9-921e-d7989c172773_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentDomain_46167f08-2a00-41e9-a444-b8ca8f6e735e" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SegmentDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementBusinessSegmentsAxis_f07c7846-6ca3-40e9-921e-d7989c172773" xlink:to="loc_us-gaap_SegmentDomain_46167f08-2a00-41e9-a444-b8ca8f6e735e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_NorthAmericanOTCHealthcareMember_38b678d8-6507-44f5-9c3e-1bcac0595db3" xlink:href="pbh-20250630.xsd#pbh_NorthAmericanOTCHealthcareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_46167f08-2a00-41e9-a444-b8ca8f6e735e" xlink:to="loc_pbh_NorthAmericanOTCHealthcareMember_38b678d8-6507-44f5-9c3e-1bcac0595db3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_InternationalOTCHealthcareMember_1d139e76-6012-45f9-8e00-17225d8248a6" xlink:href="pbh-20250630.xsd#pbh_InternationalOTCHealthcareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SegmentDomain_46167f08-2a00-41e9-a444-b8ca8f6e735e" xlink:to="loc_pbh_InternationalOTCHealthcareMember_1d139e76-6012-45f9-8e00-17225d8248a6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_f1099477-30db-4489-94bd-7c0277f86a76" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductOrServiceAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_ScheduleOfEntityWideInformationRevenueFromExternalCustomersByProductsAndServicesTable_40887f75-08a1-4e71-8cc8-7b60d46ad9e2" xlink:to="loc_srt_ProductOrServiceAxis_f1099477-30db-4489-94bd-7c0277f86a76" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_f1099477-30db-4489-94bd-7c0277f86a76_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_ProductOrServiceAxis_f1099477-30db-4489-94bd-7c0277f86a76" xlink:to="loc_srt_ProductsAndServicesDomain_f1099477-30db-4489-94bd-7c0277f86a76_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ProductsAndServicesDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_ProductOrServiceAxis_f1099477-30db-4489-94bd-7c0277f86a76" xlink:to="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_AnalgesicsMember_7628e5c7-77da-4662-9066-375038224750" xlink:href="pbh-20250630.xsd#pbh_AnalgesicsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_AnalgesicsMember_7628e5c7-77da-4662-9066-375038224750" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_CoughAndColdMember_60c708a9-e1d1-4688-8364-350517140522" xlink:href="pbh-20250630.xsd#pbh_CoughAndColdMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_CoughAndColdMember_60c708a9-e1d1-4688-8364-350517140522" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_WomensHealthMember_a32cc97d-2958-453f-ac76-b55ac1724d7c" xlink:href="pbh-20250630.xsd#pbh_WomensHealthMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_WomensHealthMember_a32cc97d-2958-453f-ac76-b55ac1724d7c" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_GastrointestinalMember_1fcc3a90-0a84-49e3-a404-ca3723c42709" xlink:href="pbh-20250630.xsd#pbh_GastrointestinalMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_GastrointestinalMember_1fcc3a90-0a84-49e3-a404-ca3723c42709" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_EyeAndEarCareMember_2bf746f4-0253-4b18-a3d5-6a45c87d3996" xlink:href="pbh-20250630.xsd#pbh_EyeAndEarCareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_EyeAndEarCareMember_2bf746f4-0253-4b18-a3d5-6a45c87d3996" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_DermatologicalsMember_ee918bc2-2c19-4130-98e5-3870f18ccdf4" xlink:href="pbh-20250630.xsd#pbh_DermatologicalsMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_DermatologicalsMember_ee918bc2-2c19-4130-98e5-3870f18ccdf4" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_OralCareMember_a65aca2e-3e93-4d69-ab40-2eed5ca86d41" xlink:href="pbh-20250630.xsd#pbh_OralCareMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_OralCareMember_a65aca2e-3e93-4d69-ab40-2eed5ca86d41" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_OtherOtcMember_f98b908b-48e8-425b-b664-e76c14ca9a27" xlink:href="pbh-20250630.xsd#pbh_OtherOtcMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ProductsAndServicesDomain_95ba50ce-2bb4-468f-a4fb-7be04230b163" xlink:to="loc_pbh_OtherOtcMember_f98b908b-48e8-425b-b664-e76c14ca9a27" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeographicAreasRevenuesFromExternalCustomersAbstract_87495c08-7b76-4e0e-83b3-8ba85581bedd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_GeographicAreasRevenuesFromExternalCustomersAbstract"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_EntityWideInformationRevenueFromExternalCustomerLineItems_16b7f9e6-0c11-4b5e-acdd-bf1b782caf2d" xlink:to="loc_us-gaap_GeographicAreasRevenuesFromExternalCustomersAbstract_87495c08-7b76-4e0e-83b3-8ba85581bedd" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5ff51321-95f5-4ce8-8416-4b3d1385e85d" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_GeographicAreasRevenuesFromExternalCustomersAbstract_87495c08-7b76-4e0e-83b3-8ba85581bedd" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_5ff51321-95f5-4ce8-8416-4b3d1385e85d" xlink:type="arc" order="1"/>
  </link:definitionLink>
  <link:roleRef roleURI="http://www.prestigebrandsinc.com/role/SubsequentEventsDetails" xlink:type="simple" xlink:href="pbh-20250630.xsd#SubsequentEventsDetails"/>
  <link:definitionLink xlink:role="http://www.prestigebrandsinc.com/role/SubsequentEventsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventLineItems_7ea6f439-a04c-4bc8-8468-bdbce26e914f" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_us-gaap_SubsequentEventLineItems_7ea6f439-a04c-4bc8-8468-bdbce26e914f" xlink:to="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeAxis_4d46637a-4a34-4699-a813-65634741a57b" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:to="loc_us-gaap_SubsequentEventTypeAxis_4d46637a-4a34-4699-a813-65634741a57b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_4d46637a-4a34-4699-a813-65634741a57b_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_4d46637a-4a34-4699-a813-65634741a57b" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_4d46637a-4a34-4699-a813-65634741a57b_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventTypeDomain_e2dc2032-5d57-439a-bc83-49d7cf2433b8" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventTypeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_SubsequentEventTypeAxis_4d46637a-4a34-4699-a813-65634741a57b" xlink:to="loc_us-gaap_SubsequentEventTypeDomain_e2dc2032-5d57-439a-bc83-49d7cf2433b8" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsequentEventMember_d34d5500-0ec5-42bb-9287-7a193b835edd" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_SubsequentEventMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventTypeDomain_e2dc2032-5d57-439a-bc83-49d7cf2433b8" xlink:to="loc_us-gaap_SubsequentEventMember_d34d5500-0ec5-42bb-9287-7a193b835edd" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_TitleOfIndividualAxis_d4eb9773-8b7a-4ddb-b37f-3bce50b89219" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_TitleOfIndividualAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:to="loc_srt_TitleOfIndividualAxis_d4eb9773-8b7a-4ddb-b37f-3bce50b89219" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_d4eb9773-8b7a-4ddb-b37f-3bce50b89219_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_TitleOfIndividualWithRelationshipToEntityDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_TitleOfIndividualAxis_d4eb9773-8b7a-4ddb-b37f-3bce50b89219" xlink:to="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_d4eb9773-8b7a-4ddb-b37f-3bce50b89219_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_cc3fa369-ed96-4d3d-9113-b4d3a6f113c9" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_TitleOfIndividualWithRelationshipToEntityDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_TitleOfIndividualAxis_d4eb9773-8b7a-4ddb-b37f-3bce50b89219" xlink:to="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_cc3fa369-ed96-4d3d-9113-b4d3a6f113c9" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_DirectorMember_ad6bc784-7e1a-499c-b9d0-90117ae80466" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_DirectorMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_cc3fa369-ed96-4d3d-9113-b4d3a6f113c9" xlink:to="loc_srt_DirectorMember_ad6bc784-7e1a-499c-b9d0-90117ae80466" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_8e191f22-f766-4515-9b25-0b6d418d33df" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_AwardTypeAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:to="loc_us-gaap_AwardTypeAxis_8e191f22-f766-4515-9b25-0b6d418d33df" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8e191f22-f766-4515-9b25-0b6d418d33df_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_AwardTypeAxis_8e191f22-f766-4515-9b25-0b6d418d33df" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_8e191f22-f766-4515-9b25-0b6d418d33df_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_642ff339-36ee-40ac-ac4d-e1ea15792f50" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_AwardTypeAxis_8e191f22-f766-4515-9b25-0b6d418d33df" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_642ff339-36ee-40ac-ac4d-e1ea15792f50" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_08da6e3c-90ed-4a81-a528-3110eb25daa1" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_642ff339-36ee-40ac-ac4d-e1ea15792f50" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_08da6e3c-90ed-4a81-a528-3110eb25daa1" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAxis_3bfd4eef-28b1-4eb7-b84b-06b5764cc0f6" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:to="loc_us-gaap_BusinessAcquisitionAxis_3bfd4eef-28b1-4eb7-b84b-06b5764cc0f6" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_3bfd4eef-28b1-4eb7-b84b-06b5764cc0f6_default" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_3bfd4eef-28b1-4eb7-b84b-06b5764cc0f6" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_3bfd4eef-28b1-4eb7-b84b-06b5764cc0f6_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8a524f06-6dc5-4c9f-ae0c-8c4d164a88d7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessAcquisitionAcquireeDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_BusinessAcquisitionAxis_3bfd4eef-28b1-4eb7-b84b-06b5764cc0f6" xlink:to="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8a524f06-6dc5-4c9f-ae0c-8c4d164a88d7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_Pillar5PharmaMember_f98696b4-3f95-4da4-91b6-c1edbb29f53f" xlink:href="pbh-20250630.xsd#pbh_Pillar5PharmaMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_BusinessAcquisitionAcquireeDomain_8a524f06-6dc5-4c9f-ae0c-8c4d164a88d7" xlink:to="loc_pbh_Pillar5PharmaMember_f98696b4-3f95-4da4-91b6-c1edbb29f53f" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementScenarioAxis_b5f76ddf-e381-45c7-ac30-8ea3f6c1c5a8" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_StatementScenarioAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_us-gaap_SubsequentEventTable_3865ceab-b10c-4872-ad19-40019e074e15" xlink:to="loc_srt_StatementScenarioAxis_b5f76ddf-e381-45c7-ac30-8ea3f6c1c5a8" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_b5f76ddf-e381-45c7-ac30-8ea3f6c1c5a8_default" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_srt_StatementScenarioAxis_b5f76ddf-e381-45c7-ac30-8ea3f6c1c5a8" xlink:to="loc_srt_ScenarioUnspecifiedDomain_b5f76ddf-e381-45c7-ac30-8ea3f6c1c5a8_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioUnspecifiedDomain_26c7d1f7-2c6a-4ef1-9a71-33369150c8d6" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ScenarioUnspecifiedDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_srt_StatementScenarioAxis_b5f76ddf-e381-45c7-ac30-8ea3f6c1c5a8" xlink:to="loc_srt_ScenarioUnspecifiedDomain_26c7d1f7-2c6a-4ef1-9a71-33369150c8d6" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ScenarioForecastMember_033e30f9-2ea7-4a28-b531-8d5455be637d" xlink:href="https://xbrl.fasb.org/srt/2025/elts/srt-2025.xsd#srt_ScenarioForecastMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_srt_ScenarioUnspecifiedDomain_26c7d1f7-2c6a-4ef1-9a71-33369150c8d6" xlink:to="loc_srt_ScenarioForecastMember_033e30f9-2ea7-4a28-b531-8d5455be637d" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_74005812-68c9-43cc-8498-b59bd14ce403" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_7ea6f439-a04c-4bc8-8468-bdbce26e914f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_74005812-68c9-43cc-8498-b59bd14ce403" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_7776c5fd-633c-45b1-9949-bb8200135da7" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_7ea6f439-a04c-4bc8-8468-bdbce26e914f" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_7776c5fd-633c-45b1-9949-bb8200135da7" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_pbh_CommonStockNumberOfSharesDeliveredForEachVestedRestrictedStockUnit_d5c23fc2-2084-49a8-bc33-bd899d79e705" xlink:href="pbh-20250630.xsd#pbh_CommonStockNumberOfSharesDeliveredForEachVestedRestrictedStockUnit"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_7ea6f439-a04c-4bc8-8468-bdbce26e914f" xlink:to="loc_pbh_CommonStockNumberOfSharesDeliveredForEachVestedRestrictedStockUnit_d5c23fc2-2084-49a8-bc33-bd899d79e705" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_7a5a86d4-befa-4f94-819b-3f10360991ad" xlink:href="https://xbrl.fasb.org/us-gaap/2025/elts/us-gaap-2025.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_SubsequentEventLineItems_7ea6f439-a04c-4bc8-8468-bdbce26e914f" xlink:to="loc_us-gaap_BusinessCombinationConsiderationTransferred1_7a5a86d4-befa-4f94-819b-3f10360991ad" xlink:type="arc" order="3"/>
  </link:definitionLink>
</link:linkbase>
