<SEC-DOCUMENT>0001209191-14-067085.txt : 20141106
<SEC-HEADER>0001209191-14-067085.hdr.sgml : 20141106
<ACCEPTANCE-DATETIME>20141106180746
ACCESSION NUMBER:		0001209191-14-067085
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20141104
FILED AS OF DATE:		20141106
DATE AS OF CHANGE:		20141106

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Xenon Pharmaceuticals Inc.
		CENTRAL INDEX KEY:			0001582313
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				980661854
		STATE OF INCORPORATION:			A1
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		200 - 3650 GILMORE WAY
		CITY:			BURNABY
		STATE:			A1
		ZIP:			V5G 48W
		BUSINESS PHONE:		(604) 484-3300

	MAIL ADDRESS:	
		STREET 1:		200 - 3650 GILMORE WAY
		CITY:			BURNABY
		STATE:			A1
		ZIP:			V5G 48W

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MX Associates, LLP
		CENTRAL INDEX KEY:			0001624453

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36687
		FILM NUMBER:		141202120

	BUSINESS ADDRESS:	
		STREET 1:		5375 MEDPACE WAY
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45227
		BUSINESS PHONE:		604-484-3300

	MAIL ADDRESS:	
		STREET 1:		5375 MEDPACE WAY
		CITY:			CINCINNATI
		STATE:			OH
		ZIP:			45227
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2014-11-04</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001582313</issuerCik>
        <issuerName>Xenon Pharmaceuticals Inc.</issuerName>
        <issuerTradingSymbol>XENE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001624453</rptOwnerCik>
            <rptOwnerName>MX Associates, LLP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5375 MEDPACE WAY</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CINCINNATI</rptOwnerCity>
            <rptOwnerState>OH</rptOwnerState>
            <rptOwnerZipCode>45227</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Series E Preferred Shares</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F3"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Shares</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>1474660</value>
                    <footnoteId id="F1"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Reflects a 1-for-4.86 reverse stock split of the Issuer's outstanding shares effected October 1, 2014 (the &quot;Reverse Stock Split&quot;).</footnote>
        <footnote id="F2">Reflects the automatic conversion of each share of Series E Preferred Shares into 1.2 shares of Common Shares to occur upon the closing of the Issuer's initial public offering.</footnote>
        <footnote id="F3">Each share has no expiration date.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Barbara Mery, Attorney-in-fact for MX Associates, Inc.</signatureName>
        <signatureDate>2014-11-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
<TEXT>
<HTML>
<HEAD>
</HEAD>
<BODY>
<PRE>

                               POWER OF ATTORNEY

     The undersigned, as a Section 16 reporting person of Xenon Pharmaceuticals
Inc. (the "Company"), hereby constitutes and appoints Wilson Sonsini Goodrich &
Rosati, P.C., the undersigned's true and lawful attorney-in-fact to:

     1.  complete and execute Forms ID, 3,4 and 5 and other forms and all
         amendments thereto as such attorney-in-fact shall in his or her
         discretion determine to be required or advisable pursuant to Section 16
         of the Securities Exchange Act of 1934 (as amended) and the rules and
         regulations promulgated thereunder, or any successor laws and
         regulations, as a consequence of the undersigned's ownership,
         acquisition or disposition of securities of the Company; and

     2.  do all acts necessary in order to file such forms with the Securities
         and Exchange Commission, any securities exchange or national
         association, the Company and such other person or agency as the
         attorney-in-fact shall deem appropriate.

     The undersigned hereby ratifies and confirms all that said
attorneys-in-fact and agents shall do or cause to be done by virtue hereof.  The
undersigned acknowledges that the foregoing attorneys-in-fact, in serving in
such capacity at the request of the undersigned, are not assuming, nor is the
Company assuming, any of the undersigned's responsibilities to comply with
Section 16 of the Securities Exchange Act of 1934 (as amended).

     This Power of Attorney shall remain in full force and effect until the
undersigned is no longer required to file Forms ID, 3, 4 and 5 with respect to
the undersigned's holdings of and transactions in securities issued by the
Company, unless earlier revoked by the undersigned in a signed writing
delivered to the Company and the foregoing attorneys-in-fact.

     IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be
executed as of this 5th day of November, 2014.

                                   MX ASSOCIATES, LLP


                                   By:    /s/ August J. Troendle
                                      ----------------------------------

                                   Name:  August J. Troendle
                                        --------------------------------

                                   Title: Managing Partner
                                         -------------------------------

</PRE>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
