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Share Capital (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Mar. 31, 2021 | Aug. 31, 2020 | Feb. 29, 2020 | Jan. 31, 2020 | Nov. 30, 2019 | Mar. 31, 2018 | Mar. 31, 2021 | Mar. 31, 2020 | Jun. 30, 2021 | Dec. 31, 2019 | Dec. 31, 2018
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amount offered for issuance of common stock |  |  |  |  |  |  |  | $ 102,456 |  |  |
Warrants outstanding to purchase common stock |  |  |  |  |  |  |  |  | 1,081,081 |  |
Warrants exercise description | The Company may not affect the exercise of any Pre-Funded Warrant, and a holder will not be entitled to exercise any portion of any Pre-Funded Warrant that, upon giving effect to such exercise, would cause: (i) the aggregate number of common shares beneficially owned by such holder, together with its affiliates, to exceed 4.99% of the total number of common shares outstanding immediately after giving effect to the exercise; or (ii) the combined voting power of the Company’s securities beneficially owned by such holder, together with its affiliates, to exceed 4.99% of the combined voting power of all of the Company’s securities immediately outstanding after giving effect to the exercise, which percentage may be changed at the holder’s election to a higher or lower percentage not in excess of 19.99% upon at least 61 days’ notice to the Company. |  |  |  |  |  |  |  |  |  |
Series1 Preferred Shares |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Conversion of shares |  |  |  |  |  |  |  |  |  |  | 1,852,000
Common Shares [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Conversion of shares |  |  |  |  |  |  |  |  |  |  | 1,852,000
BVF Partners L.P [Member] | Exchange Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Estimated weighted average cancellation price per share of common stock |  |  |  |  |  | $ 7.61 |  |  |  |  |
BVF Partners L.P [Member] | Exchange Agreement [Member] | Series1 Preferred Shares |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares issued |  |  |  |  |  | 2,868,000 |  |  |  |  |
Preferred shares convertible into common shares |  |  |  |  |  | one-for-one |  |  |  |  |
Maximum beneficial ownership limitation percentage for conversion of common stock issued and outstanding |  |  |  |  |  | 9.99% |  |  |  |  |
Maximum beneficial ownership limitation upon notice, percentage for conversion of common stock issued and outstanding |  |  |  |  |  | 19.99% |  |  |  |  |
Maximum beneficial percentage hold for conversion of number Of common stock issued and outstanding |  |  |  |  |  | 5.00% |  |  |  |  |
Minimum beneficial percentage hold for conversion of number Of common stock issued and outstanding. |  |  |  |  |  | 5.00% |  |  |  |  |
BVF Partners L.P [Member] | Exchange Agreement [Member] | Common Shares [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares cancelled |  |  |  |  |  | 2,868,000 |  |  |  |  |
Common Shares [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares issued |  |  |  |  |  |  | 5,868,135 | 6,759,187 |  |  |
Amount offered for issuance of common stock |  |  |  |  |  |  | $ 99,846 | $ 102,456 |  |  |
Jefferies and Stifel [Member] | Underwritten Public Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amount offered for issuance of common stock | $ 107,922 |  |  |  |  |  |  |  |  |  |
Shares issued | 5,135,135 |  |  |  |  |  |  |  |  |  |
Shares price | $ 18.50 |  |  |  |  |  | $ 18.50 |  |  |  |
Warrants outstanding to purchase common stock | 1,081,081 |  |  |  |  |  | 1,081,081 |  |  |  |
Warrants issued price per pre funded warrant | $ 18.4999 |  |  |  |  |  | $ 18.4999 |  |  |  |
Warrants exercise price per common share | $ 0.0001 |  |  |  |  |  | $ 0.0001 |  |  |  |
Sale proceeds from issuance of pre funded warrants | $ 18,769 |  |  |  |  |  |  |  |  |  |
Number of warrants exercised |  |  |  |  |  |  |  |  | 0 |  |
Jefferies and Stifel [Member] | At-The-Market Equity Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amount offered for issuance of common stock |  |  |  | $ 37,796 |  |  |  |  |  | $ 10,729 |
Sale proceeds of common shares |  |  |  |  |  |  |  |  | 10,693,000 |  |
Jefferies and Stifel [Member] | At-The-Market Equity Offering [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amount offered for issuance of common stock |  |  |  |  | $ 50,000 |  |  |  |  |  |
Amount offered for issuance of common stock |  | $ 100,000 |  |  |  |  |  |  |  |  |
Jefferies and Stifel [Member] | At-The-Market Equity Offering [Member] | Common Shares [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares issued |  |  |  | 2,446,687 |  |  |  |  | 733,000 | 805,643 |
Jefferies and Stifel [Member] | Over Allotment [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares issued | 810,810 |  |  |  |  |  |  |  |  |  |
Jefferies, Stifel and Guggenheim Securities, LLC [Member] | Underwritten Public Offering [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amount offered for issuance of common stock |  |  | $ 8,395 | $ 56,265 |  |  |  |  |  |  |
Jefferies, Stifel and Guggenheim Securities, LLC [Member] | Underwritten Public Offering [Member] | Common Shares [Member] |  |  |  |  |  |  |  |  |  |  |
Share Capital [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares issued |  |  | 562,500 | 3,750,000 |  |  |  |  |  |  |
Shares price |  |  |  | $ 16.00 |  |  |  |  |  |  |

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