<SEC-DOCUMENT>0001564590-22-008105-index.html : 20220301
<SEC-HEADER>0001564590-22-008105.hdr.sgml : 20220301
<ACCEPTANCE-DATETIME>20220301171246
ACCESSION NUMBER:		0001564590-22-008105
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20220301
DATE AS OF CHANGE:		20220301

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Xenon Pharmaceuticals Inc.
		CENTRAL INDEX KEY:			0001582313
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				980661854
		STATE OF INCORPORATION:			A1
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-260010
		FILM NUMBER:		22699614

	BUSINESS ADDRESS:	
		STREET 1:		200 - 3650 GILMORE WAY
		CITY:			BURNABY
		STATE:			A1
		ZIP:			V5G 48W
		BUSINESS PHONE:		(604) 484-3300

	MAIL ADDRESS:	
		STREET 1:		200 - 3650 GILMORE WAY
		CITY:			BURNABY
		STATE:			A1
		ZIP:			V5G 48W
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>xene-424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: xene-424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>2
<FILENAME>xene-exfilingfees_177.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 2 - file: xene-exfilingfees_177.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>gyu1yhw1mz2i000003.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: gyu1yhw1mz2i000003.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>gyu1yhw1mz2i000001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: gyu1yhw1mz2i000001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>gyu1yhw1mz2i000002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: gyu1yhw1mz2i000002.jpg

</DOCUMENT>
</SEC-DOCUMENT>