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Product Revenue, Net

12 Months Ended

Dec. 31, 2025

Product Revenue, Net

Product Revenue, Net

4.           Product Revenue, Net

ARCALYST

​

The Company derives substantially all of its product revenue, net from sales of ARCALYST in the United States, which was as follows:

​

​	​	​	​	​	​	​	​	​	​
​	​	Years Ended
​	​	December 31,
​	​	2025		​	2024		​	2023
Product Revenue, net	​	$	677,564	​	$	417,029	​	$	233,176

​

​

The following tables summarizes balances and activity in each of the product revenue allowance and reserve categories for the years ended December 31, 2025 and 2024:

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Contractual

​

Government

​

​

​

​

​

​

Adjustments

​

Rebates

​

Returns

​

Total

Balance at December 31, 2024

​

$

3,495

​

$

8,640

​

$

2,294

​

$

14,429

Current provisions relating to sales in the current year

​

​

36,209

​

​

26,882

​

​

1,704

​

​

64,795

Adjustments relating to prior years

​

​

—

​

​

(2,306)

​

​

(718)

​

​

(3,024)

Payments/returns relating to sales in the current year

​

​

(31,650)

​

​

(15,995)

​

​

—

​

​

(47,645)

Payments/returns relating to sales in the prior years

​

​

(3,495)

​

​

(5,338)

​

​

(156)

​

​

(8,989)

Balance at December 31, 2025

​

$

4,559

​

$

11,883

​

$

3,124

​

$

19,566

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

​

Contractual

​

Government

​

​

​

​

​

​

Adjustments

​

Rebates

​

Returns

​

Total

Balance at December 31, 2023

​

$

2,022

​

$

3,775

​

$

341

​

$

6,138

Current provisions relating to sales in the current year

​

​

24,738

​

​

18,436

​

​

1,296

​

​

44,470

Adjustments relating to prior years

​

​

(31)

​

​

(155)

​

​

836

​

​

650

Payments/returns relating to sales in the current year

​

​

(21,277)

​

​

(9,796)

​

​

—

​

​

(31,073)

Payments/returns relating to sales in the prior years

​

​

(1,957)

​

​

(3,620)

​

​

(179)

​

​

(5,756)

Balance at December 31, 2024

​

$

3,495

​

$

8,640

​

$

2,294

​

$

14,429

​

Total revenue-related reserves as of December 31, 2025 and 2024, included in the Company’s consolidated balance sheets, are summarized as follows:

​

​	​	​	​	​	​	​
​	​	December 31,		​	December 31,
​	​	2025		​	2024
Reduction of accounts receivable	​	$	(831)	​	$	(444)
Components of other current liabilities	​	​	20,397	​	​	14,873
Total revenue-related reserves	​	$	19,566	​	$	14,429

​

pl

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- References

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- Definition

The entire disclosure of revenue from contract with customer to transfer good or service and to transfer nonfinancial asset. Includes, but is not limited to, disaggregation of revenue, credit loss recognized from contract with customer, judgment and change in judgment related to contract with customer, and asset recognized from cost incurred to obtain or fulfill contract with customer. Excludes insurance and lease contracts.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 7
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-7

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 9
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-9

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 10
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-10

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 15
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-15

Reference 5: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-12

Reference 6: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-12

Reference 7: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12
-Subparagraph (c)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-12

Reference 8: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-12

Reference 9: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 12
-Subparagraph (e)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-12

Reference 10: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 13
-Subparagraph (b)(2)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-13

Reference 11: http://www.xbrl.org/2003/role/disclosureRef
-Name Accounting Standards Codification
-Topic 606
-Publisher FASB
-URI https://asc.fasb.org/606/tableOfContent

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