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CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE INCOME (LOSS) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenue:      
Revenue $ 677,564 $ 423,239 $ 270,259
Operating expenses:      
Cost of goods sold 77,673 60,910 33,407
Collaboration expenses 229,545 128,311 56,524
Research and development 96,853 111,623 76,097
Selling, general and administrative 196,272 168,011 129,427
Total operating expenses 600,343 468,855 295,455
Income (loss) from operations 77,221 (45,616) (25,196)
Other income, net 11,647 9,464 8,544
Income (loss) before income taxes 88,868 (36,152) (16,652)
Benefit (provision) for income taxes (29,863) (7,041) 30,736
Net income (loss) $ 59,005 $ (43,193) $ 14,084
Net income (loss) per share attributable to ordinary shareholders, basic $ 0.8 $ (0.6) $ 0.2
Net income (loss) per share attributable to ordinary shareholders, diluted $ 0.75 $ (0.6) $ 0.2
Weighted average ordinary shares outstanding, basic 74,200,924 71,424,159 70,058,952
Weighted average ordinary shares outstanding, diluted 78,979,030 71,424,159 71,922,915
Comprehensive income (loss):      
Net income (loss) $ 59,005 $ (43,193) $ 14,084
Other comprehensive income (loss):      
Unrealized gain (loss) on short-term investments and currency translation adjustments, net of tax 138 (169) (38)
Total other comprehensive income (loss) 138 (169) (38)
Total comprehensive income (loss) 59,143 (43,362) 14,046
Product revenue, net      
Revenue:      
Revenue $ 677,564 417,029 233,176
License and collaboration revenue      
Revenue:      
Revenue   $ 6,210 $ 37,083