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Segment Information and Geographic Data (Tables)

12 Months Ended

Dec. 31, 2025

Segment Information and Geographic Data

Schedule of selected financial information with respect to the company's single operating segment

​	​	​	​	​	​	​	​	​	​
​	​	Years Ended
​	​	December 31,
​	​ ​ ​	2025		​	2024		​ ​ ​	2023
Revenue:	​	​	​	​	​	​	​	​	​
Product revenue, net	​	$	677,564	​	$	417,029	​	$	233,176
License and collaboration revenue	​	​	-	​	​	6,210	​	​	37,083
Total revenue	​	​	677,564	​	​	423,239	​	​	270,259
Operating expenses:	​	​	​	​	​	​	​	​	​
Cost of goods sold	​	​	77,673	​	​	60,910	​	​	33,407
Collaboration expenses	​	​	229,545	​	​	128,311	​	​	56,524
Direct research and development expenses by program:	​	​	​	​	​	​	​	​	​
ARCALYST	​	​	1,040	​	​	1,080	​	​	2,628
KPL-387	​	​	47,265	​	​	11,221	​	​	2,537
KPL-1161	​	​	4,198	​	​	581	​	​	-
Abiprubart	​	​	6,122	​	​	59,459	​	​	28,388
Vixarelimab	​	​	44	​	​	1,530	​	​	7,717
Unallocated research and development expenses	​	​	38,184	​	​	37,752	​	​	34,827
Selling, general and administrative	​	​	196,272	​	​	168,011	​	​	129,427
Total operating expenses	​	​	600,343	​	​	468,855	​	​	295,455
Other income, net (1)	​	​	11,647	​	​	9,464	​	​	8,544
Income (loss) before income taxes	​	​	88,868	​	​	(36,152)	​	​	(16,652)
Benefit (provision) for income taxes	​	​	(29,863)	​	​	(7,041)	​	​	30,736
Net income (loss)	​	$	59,005	​	$	(43,193)	​	$	14,084
​	​	​	​	​	​	​	​	​	​
Other significant non-cash items:	​		​	​		​	​		​
Share-based compensation expense	​	$	37,003	​	$	30,693	​	$	27,149
Non-cash lease expense	​	​	3,666	​	​	3,136	​	​	3,054
Deferred income taxes	​	​	13,002	​	​	8,132	​	​	(33,788)

​

(1) Includes interest income of $11,636, $9,036 and $8,227 for the years ended December 31, 2025, 2024 and 2023 respectively.

Schedule of total revenue by geographic region of the customer

​

​	​	​	​	​	​	​	​	​	​
​	​	Years Ended
​	​	December 31,
​	​	2025		​	2024		​ ​ ​	2023
Revenue:	​	​	​	​	​	​	​	​	​
United States	​	$	676,750	​	$	421,434	​	$	269,772
United Kingdom	​	​	814	​	​	930	​	​	487
Rest of world	​	​	-	​	​	875	​	​	-
Total revenue	​	$	677,564	​	$	423,239	​	$	270,259

Schedule of property and equipment, net by geographic region

​

​	​	​	​	​	​	​
​	​	Years Ended
​	​	December 31,
​	​	2025		​	2024
Property and Equipment, net	​	​	​	​	​	​
United States	​	$	1,608	​	$	313
United Kingdom	​	​	76	​	​	99
Rest of world	​	​	259	​	​	250
Total property and equipment, net	​	$	1,943	​	$	662

​

X

- Definition

Tabular disclosure of long-lived assets, excluding financial instruments, long-term customer relationships of a financial institution, mortgage rights, deferred policy acquisition costs, and deferred tax assets, by geographic areas located in the entity's country of domicile and foreign countries in which the entity holds assets.

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Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

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