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Commitments and Contingencies (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Manufacturing commitments      
Non-cancelable purchase commitments $ 175,704    
Amount of purchase commitment obligation due within one year 46,924    
Research and development 96,853 $ 111,623 $ 76,097
Abiprubart      
Manufacturing commitments      
Research and development 2,500    
PSOs      
Long-term incentive plan      
Performance cash award expense 0    
2018 Plan | PSOs      
Long-term incentive plan      
Estimated amount of cash award in the event performance goals are achieved $ 23,118