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Loss per Share - Anti-dilutive common equivalent shares (Details) - shares
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Loss per Share    
Total anti-dilutive common equivalent shares 202,514,745 197,662,478
Outstanding options to purchase common shares    
Loss per Share    
Total anti-dilutive common equivalent shares 25,140,262 25,287,670
Outstanding RSUs    
Loss per Share    
Total anti-dilutive common equivalent shares 5,021,783 56,224
Outstanding shares under ESPP    
Loss per Share    
Total anti-dilutive common equivalent shares 34,116  
Outstanding warrants    
Loss per Share    
Total anti-dilutive common equivalent shares 36,078,620 36,078,620
Outstanding Special Shares and options to purchase Special Shares    
Loss per Share    
Total anti-dilutive common equivalent shares 136,239,964 136,239,964