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Product Revenues, Accounts Receivable, and Reserves for Product Sales - Schedule of Disaggregation of Product Revenue by Major Source (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]      
Total product revenue, net $ 396,591 $ 75,422 $ 66,563
EMPAVELI      
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]      
Total product revenue, net 91,033 65,092 15,147
SYFOVRE [Member]      
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]      
Total product revenue, net 275,248    
Product revenue, net [Member]      
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]      
Total product revenue, net $ 366,281 $ 65,092 $ 15,147