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Product Revenues, Accounts Receivable, and Reserves for Product Sales - Schedule of Disaggregation of Product Revenue by Major Source (Detail) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]    
Total Product revenue, net $ 172,325 $ 44,846
EMPAVELI [Member]    
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]    
Total Product revenue, net 25,610 20,440
SYFOVRE [Member]    
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]    
Total Product revenue, net 137,465 18,360
Product Revenue, Net [Member]    
Product Revenues Accounts Receivable And Reserves For Product Sales [Line Items]    
Total Product revenue, net $ 163,075 $ 38,800