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License and Collaboration Agreements - Additional Information (Detail) |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended | 47 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Nov. 30, 2020 USD ($) | Oct. 27, 2020 USD ($) | Jan. 31, 2024 USD ($) | Oct. 31, 2023 USD ($) | Apr. 30, 2023 USD ($) | Jan. 31, 2023 USD ($) | Jun. 30, 2022 USD ($) | Apr. 30, 2022 USD ($) | Aug. 31, 2021 USD ($) | Sep. 30, 2024 USD ($) License | Sep. 30, 2023 USD ($) | Sep. 30, 2024 USD ($) License | Sep. 30, 2023 USD ($) | Dec. 31, 2023 USD ($) | Sep. 30, 2024 USD ($) License | Jan. 31, 2021 USD ($) | Oct. 31, 2020 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Development cost reimbursement received |  |  | $ 15,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |  |  |  | $ 196,830,000 | $ 110,399,000 | $ 568,839,000 | $ 250,214,000 |  |  |  |
Number of licensed products | License |  |  |  |  |  |  |  |  |  | 2 |  | 2 |  |  | 2 |  |
EMPAVELI [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |  |  |  | $ 24,611,000 | 23,901,000 | $ 74,733,000 | 66,643,000 |  |  |  |
SYFOVRE [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |  |  |  | 151,960,000 | 75,281,000 | 444,049,000 | 160,983,000 |  |  |  |
Regulatory milestone payments |  |  | 3,000,000 | $ 2,000,000 | $ 2,300,000 |  |  |  |  |  |  |  |  |  |  |  |
Royalty expense |  |  |  |  |  |  |  |  |  | 4,900,000 |  | 14,400,000 |  |  |  |  |
Regulatory milestone incurred |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 5,000,000 |  |  |
EMPAVELI and Aspaveli [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone payments based on annual sales milestones |  |  | 1,500,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty expense |  |  |  |  |  |  |  |  |  | 1,800,000 |  | 5,000,000 |  |  |  |  |
Swedish Orphan Biovitrum AB (Publ) [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Royalty Revenue |  |  |  |  |  |  |  |  |  | 5,000,000 | 2,700,000 | $ 13,900,000 | 800,000 |  |  |  |
Collaboration and License Agreement [Member] | Swedish Orphan Biovitrum AB (Publ) [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment | $ 250,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone payment received for achievement of regulatory development milestone |  |  |  |  |  |  |  | $ 50,000,000 |  |  |  |  |  |  |  |  |
Development cost reimbursement received |  |  |  |  |  | $ 65,000,000 |  |  |  |  |  |  |  |  |  |  |
Waived Payment |  |  | 15,000,000 |  |  |  |  |  |  |  |  |  |  |  | $ 15,000,000 |  |
Royalties entitled to receive after first commercial sale of applicable licensed product period |  |  |  |  |  |  |  |  |  |  |  | 10 years |  |  |  |  |
Contract research and development reimbursement commitment |  | $ 80,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Contract research and development expense |  |  |  |  |  |  |  |  |  | 0 | $ 0 | $ 0 | $ 0 |  | 65,000,000 |  |
Contract research and development current |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,000,000 |  |  |
Remaining reimbursement payment |  |  | 15,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaboration and License Agreement [Member] | Swedish Orphan Biovitrum AB (Publ) [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate milestone payments upon achievement of specified one time regulatory development and commercial milestone events |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 915,000,000
Development cost reimbursement |  |  |  |  |  |  |  |  |  |  |  | 80,000,000 |  |  |  |  |
University of Pennsylvania [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Annual maintenance fees |  |  |  |  |  |  |  |  |  |  |  | 100,000 |  |  |  |  |
Development milestone achievement |  |  |  |  |  |  | $ 5,000,000 |  | $ 1,000,000 |  |  |  |  |  |  |  |
University of Pennsylvania [Member] | EMPAVELI and Aspaveli [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestone payments based on annual sales milestones |  |  |  |  |  | $ 1,000,000 |  |  |  |  |  |  |  |  |  |  |
University of Pennsylvania [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate milestones payments |  |  |  |  |  |  |  |  |  | 3,200,000 |  | 3,200,000 |  |  | 3,200,000 |  |
Milestone payments based on annual sales milestones |  |  |  |  |  |  |  |  |  |  |  | 5,000,000 |  |  |  |  |
2010 License Agreement [Member] | Maximum [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Aggregate milestones payments |  |  |  |  |  |  |  |  |  | $ 1,700,000 |  | 1,700,000 |  |  | $ 1,700,000 |  |
Milestone payments based on annual sales milestones |  |  |  |  |  |  |  |  |  |  |  | $ 2,500,000 |  |  |  |  |
Sobi Agreement and Another Licensing Transaction [Member] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Sublicense fee owed |  |  | $ 500,000 |  |  |  |  |  |  |  |  |  |  |  |  | $ 25,000,000 |

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