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Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) $ in Thousands | Total | Common Stock [Member] | Additional Paid-In Capital [Member] | Accumulated Other Comprehensive Income/(Loss) [Member] | Accumulated Deficit [Member]
--- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2022 | $ 169,872 | $ 11 | $ 2,479,596 | $ (875) | $ (2,308,860)
Beginning balance, Shares at Dec. 31, 2022 |  | 110,772,000 |  |  |
Issuance of common stock and pre-funded warrants in common stock offering | 384,387 | $ 1 | 384,386 |  |
Issuance of common stock and pre-funded warrants in common stock offering, shares |  | 4,008,000 |  |  |
Issuance of common stock upon exercise of stock options | 17,718 |  | 17,718 |  |
Issuance of common stock upon exercise of stock options, shares |  | 951,000 |  |  |
Vesting of restricted stock units, net of shares withheld for taxes | (10,999) |  | (10,999) |  |
Vesting of restricted stock units, net of shares withheld for taxes. shares |  | 448,000 |  |  |
Share-based compensation expense | 28,823 |  | 28,823 |  |
Net loss | (177,778) |  |  |  | (177,778)
Foreign currency translation | 100 |  |  | 100 |
Ending balance at Mar. 31, 2023 | 412,123 | $ 12 | 2,899,524 | (775) | (2,486,638)
Ending balance, Shares at Mar. 31, 2023 |  | 116,179,000 |  |  |
Beginning balance at Dec. 31, 2022 | 169,872 | $ 11 | 2,479,596 | (875) | (2,308,860)
Beginning balance, Shares at Dec. 31, 2022 |  | 110,772,000 |  |  |
Net loss | (440,052) |  |  |  |
Foreign currency translation | (190) |  |  |  |
Ending balance at Sep. 30, 2023 | 232,271 | $ 12 | 2,982,236 | (1,065) | (2,748,912)
Ending balance, Shares at Sep. 30, 2023 |  | 118,359,000 |  |  |
Beginning balance at Mar. 31, 2023 | 412,123 | $ 12 | 2,899,524 | (775) | (2,486,638)
Beginning balance, Shares at Mar. 31, 2023 |  | 116,179,000 |  |  |
Issuance of common stock upon exercise of stock options | 22,334 |  | 22,334 |  |
Issuance of common stock upon exercise of stock options, shares |  | 1,208,000 |  |  |
Vesting of restricted stock units, net of shares withheld for taxes | (27) |  | (27) |  |
Vesting of restricted stock units, net of shares withheld for taxes. shares |  | 119,000 |  |  |
Share-based compensation expense | 29,277 |  | 29,277 |  |
Issuance of common stock to employee stock purchase plan | 3,754 |  | 3,754 |  |
Issuance of common stock to employee stock purchase plan, shares |  | 73,000 |  |  |
Net loss | (122,037) |  |  |  | (122,037)
Foreign currency translation | (21) |  |  | (21) |
Ending balance at Jun. 30, 2023 | 345,403 | $ 12 | 2,954,862 | (796) | (2,608,675)
Ending balance, Shares at Jun. 30, 2023 |  | 117,579,000 |  |  |
Issuance of common stock upon exercise of stock options | 5,757 |  | 5,757 |  |
Issuance of common stock upon exercise of stock options, shares |  | 665,000 |  |  |
Vesting of restricted stock units, net of shares withheld for taxes | (9) |  | (9) |  |
Vesting of restricted stock units, net of shares withheld for taxes. shares |  | 115,000 |  |  |
Share-based compensation expense | 21,626 |  | 21,626 |  |
Net loss | (140,237) |  |  |  | (140,237)
Foreign currency translation | (269) |  |  | (269) |
Ending balance at Sep. 30, 2023 | 232,271 | $ 12 | 2,982,236 | (1,065) | (2,748,912)
Ending balance, Shares at Sep. 30, 2023 |  | 118,359,000 |  |  |
Beginning balance at Dec. 31, 2023 | 194,521 | $ 12 | 3,035,539 | (3,542) | (2,837,488)
Beginning balance, Shares at Dec. 31, 2023 |  | 119,556,000 |  |  |
Proceeds from settlement of capped call | 98,763 |  | 98,763 |  |
Issuance of common stock upon exercise of stock options | 9,477 |  | 9,477 |  |
Issuance of common stock upon exercise of stock options, shares |  | 714,000 |  |  |
Vesting of restricted stock units, net of shares withheld for taxes | (28) |  | (28) |  |
Vesting of restricted stock units, net of shares withheld for taxes. shares |  | 997,000 |  |  |
Share-based compensation expense | 30,349 |  | 30,349 |  |
Net loss | (66,423) |  |  |  | (66,423)
Foreign currency translation | 17 |  |  | 17 |
Ending balance at Mar. 31, 2024 | 266,676 | $ 12 | 3,174,100 | (3,525) | (2,903,911)
Ending balance, Shares at Mar. 31, 2024 |  | 121,267,000 |  |  |
Beginning balance at Dec. 31, 2023 | 194,521 | $ 12 | 3,035,539 | (3,542) | (2,837,488)
Beginning balance, Shares at Dec. 31, 2023 |  | 119,556,000 |  |  |
Proceeds from settlement of capped call | 98,763 |  |  |  |
Net loss | (161,525) |  |  |  |
Foreign currency translation | 402 |  |  |  |
Ending balance at Sep. 30, 2024 | 237,121 | $ 12 | 3,239,262 | (3,140) | (2,999,013)
Ending balance, Shares at Sep. 30, 2024 |  | 122,069,000 |  |  |
Beginning balance at Mar. 31, 2024 | 266,676 | $ 12 | 3,174,100 | (3,525) | (2,903,911)
Beginning balance, Shares at Mar. 31, 2024 |  | 121,267,000 |  |  |
Issuance of common stock upon exercise of stock options | 1,962 |  | 1,962 |  |
Issuance of common stock upon exercise of stock options, shares |  | 233,000 |  |  |
Vesting of restricted stock units, net of shares withheld for taxes. shares |  | 102,000 |  |  |
Share-based compensation expense | 29,990 |  | 29,990 |  |
Issuance of common stock to employee stock purchase plan | 3,193 |  | 3,193 |  |
Issuance of common stock to employee stock purchase plan, shares |  | 85,000 |  |  |
Net loss | (37,657) |  |  |  | (37,657)
Foreign currency translation | 163 |  |  | 163 |
Ending balance at Jun. 30, 2024 | 264,327 | $ 12 | 3,209,245 | (3,362) | (2,941,568)
Ending balance, Shares at Jun. 30, 2024 |  | 121,687,000 |  |  |
Issuance of common stock upon exercise of stock options | 2,556 |  | 2,556 |  |
Issuance of common stock upon exercise of stock options, shares |  | 112,000 |  |  |
Vesting of restricted stock units, net of shares withheld for taxes | (14) |  | (14) |  |
Vesting of restricted stock units, net of shares withheld for taxes. shares |  | 270,000 |  |  |
Share-based compensation expense | 27,475 |  | 27,475 |  |
Net loss | (57,445) |  |  |  | (57,445)
Foreign currency translation | 222 |  |  | 222 |
Ending balance at Sep. 30, 2024 | $ 237,121 | $ 12 | $ 3,239,262 | $ (3,140) | $ (2,999,013)
Ending balance, Shares at Sep. 30, 2024 |  | 122,069,000 |  |  |

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