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v3.25.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Operating Activities |  |  |
Net loss | $ (197,878) | $ (528,628) | $ (652,172)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Share-based compensation expense | 114,128 | 105,945 | 91,085
Loss on conversion of debt |  |  | 32,890
Loss on extinguishment of development liability | 1,949 |  |
Loss on disposal of fixed assets |  | 120 |
Forfeiture of accrued interest in exchange of convertible notes |  |  | 1,287
Depreciation expense | 1,797 | 1,784 | 1,552
Amortization of discounts for credit facility | 1,250 |  |
Amortization of discounts for convertible notes | 309 | 297 | 459
Accretion of discount to development liability | 8,936 | 25,996 | 26,917
Changes in operating assets and liabilities: |  |  |
Accounts receivable | (58,484) | (198,715) | 2,375
Inventory | (10,755) | (60,647) | (69,397)
Prepaid assets | 20,420 | (1,870) | (11,479)
Other current assets | 10,793 | 14,243 | 32,936
Other assets | 705 | 11,700 | 17,490
Right-of-use assets and lease liabilities | (277) | (80) | (65)
Accounts payable | 1,089 | 170 | 18,689
Accrued expenses and other liabilities | 18,152 | 34,950 | (6,312)
Net cash used in operating activities | (87,866) | (594,735) | (513,745)
Investing Activities |  |  |
Purchase of property and equipment | (403) | (773) | (1,524)
Proceeds from sale of fixed assets |  | 99 |
Purchase of available-for-sale securities |  |  | (331,863)
Proceeds from maturity of available-for-sale securities |  |  | 393,280
Net cash (used in) provided by investing activities | (403) | (674) | 59,893
Financing Activities |  |  |
Proceeds from credit facility | 365,454 |  |
Payment of issuance cost for credit facility | (7,214) |  |
Repayment of development liability | (326,533) |  |
Proceeds from settlement of capped call | 98,763 |  |
Proceeds from issuance of common stock, net of issuance costs |  |  | 380,120
Proceeds from issuance of common stock, pre-funded warrant offering, net of issuance costs |  | 384,387 |
Payments for development liability |  | (55,500) | (34,500)
Proceeds from exercise of stock options | 14,316 | 71,274 | 21,483
Proceeds from issuance of common stock under employee share purchase plan | 4,512 | 5,378 | 4,238
Payments of employee tax withholding related to equity-based compensation | (57) | (11,040) | (5,682)
Net cash provided by financing activities | 149,241 | 394,499 | 365,659
Effect of exchange rate changes on cash and cash equivalents | (659) | 135 | (488)
Net increase (decrease) in cash and cash equivalents | 60,313 | (200,775) | (88,681)
Cash, cash equivalents and restricted cash at beginning of period | 352,299 | 553,074 | 641,755
Cash, cash equivalents and restricted cash at end of period | 412,612 | 352,299 | 553,074
Reconciliation of cash, cash equivalents and restricted cash to the consolidated balance sheets: |  |  |
Cash and cash equivalents | 411,290 | 351,185 | 551,801
Restricted cash | 1,322 | 1,114 | 1,273
Total cash, cash equivalents, and restricted cash | 412,612 | 352,299 | 553,074
Supplemental disclosure of cash flow information: |  |  |
Cash paid for interest | 29,368 | 3,286 | 5,003
Cash paid for income taxes | $ 1,649 |  | 4,915
Proceeds from income tax refunds net of income taxes paid |  | $ 1,759 |
Convertible Notes exchanged for common stock |  |  | $ 98,086

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