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Segment Information | 12 Months Ended
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Dec. 31, 2024
Segment Reporting Information, Revenue for Reportable Segment [Abstract] |
Segment Information | 17. Segment Information The Company operates as a single operating segment, which is the development and commercialization of treatments across a broad range of diseases driven by complement. The Company defines its segment on the basis in which internally reported financial information is regularly reviewed by CODM to analyze financial performance, make decisions, and allocate resources. The Company’s CODM reviews consolidated net loss for purposes of assessing performance, making operating decisions, allocating resources, and planning and forecasting for future periods. The following table presents information about reported segment revenue, segment loss, and significant segment expenses as provided to the CODM with respect to the Company’s single operating segment for the years ended December 31, 2024, 2023 and 2022:
| Year Ended December 31, |
| 2024 |  |  | 2023 |  |  | 2022 |
Revenue | $ | 781,367 |  |  | $ | 396,591 |  |  | $ | 75,422 |
Less: |  |  |  |  |  |  |  |
Internal research and development costs |  | 91,881 |  |  |  | 121,931 |  |  |  | 116,525 |
Internal selling, general and administrative costs |  | 162,874 |  |  |  | 176,778 |  |  |  | 99,750 |
External commercial costs |  | 229,991 |  |  |  | 230,166 |  |  |  | 103,229 |
External research and development costs |  | 194,422 |  |  |  | 186,812 |  |  |  | 228,659 |
External general and administrative costs |  | 35,327 |  |  |  | 33,570 |  |  |  | 25,151 |
Other segment items (1) |  | 121,842 |  |  |  | 59,238 |  |  |  | 38,814 |
Share-based compensation expense |  | 114,128 |  |  |  | 105,945 |  |  |  | 91,085 |
Interest income |  | (12,773 | ) |  |  | (20,933 | ) |  |  | (8,914 | )
Interest expense |  | 40,391 |  |  |  | 29,581 |  |  |  | 32,626 |
Income tax expense |  | 1,162 |  |  |  | 2,132 |  |  |  | 669 |
Net loss | $ | (197,878 | ) |  | $ | (528,629 | ) |  | $ | (652,172 | )
(1) Other segment items include cost of sales, loss on conversion of debt, and other expenses.

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- Definition The entire disclosure for reporting segments including data and tables. 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