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v3.25.0.1

Segment Information - Schedule of Segment Revenue, Segment Profit or Loss and Significant Segment Expenses (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Less: |  |  |  |
Interest income |  | $ (12,773) | $ (20,933) | $ (8,914)
Interest expense |  | 40,391 | 29,581 | 32,626
Income tax expense |  | 1,162 | 2,132 | 669
Net Income (Loss) |  | (197,878) | (528,628) | (652,172)
Reported Segment [Member] |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Revenue |  | 781,367 | 396,591 | 75,422
Less: |  |  |  |
Internal research and development costs |  | 91,881 | 121,931 | 116,525
Internal selling, general and administrative costs |  | 162,874 | 176,778 | 99,750
External commercial costs |  | 229,991 | 230,166 | 103,229
External research and development costs |  | 194,422 | 186,812 | 228,659
External general and administrative costs |  | 35,327 | 33,570 | 25,151
Other segment items | [1] | 121,842 | 59,238 | 38,814
Share-based compensation expense |  | 114,128 | 105,945 | 91,085
Interest income |  | 12,773 | 20,933 | 8,914
Interest expense |  | 40,391 | 29,581 | 32,626
Income tax expense |  | 1,162 | 2,132 | 669
Net Income (Loss) |  | $ (197,878) | $ (528,629) | $ (652,172)
[1] | Other segment items include cost of sales, loss on conversion of debt, and other expenses.

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