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Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
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Payables and Accruals [Abstract] |  |
Accrued research and development | $ 22,782 | $ 28,318
Accrued royalties | 7,147 | 10,197
Accrued payroll liabilities | 40,888 | 51,781
Product revenue reserves | 45,145 | 16,625
Commercial costs | 20,610 | 8,715
Other | 3,612 | 12,170
Total accrued expenses | $ 140,184 | $ 127,806

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