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Segment Information
 12 Months Ended
Dec. 31, 2024
Segment Reporting Information, Revenue for Reportable Segment [Abstract]  
Segment Information

17. Segment Information

 

The Company operates as a single operating segment, which is the development and commercialization of treatments across a broad range of diseases driven by complement. The Company defines its segment on the basis in which internally reported financial information is regularly reviewed by CODM to analyze financial performance, make decisions, and allocate resources. The Company’s CODM reviews consolidated net loss for purposes of assessing performance, making operating decisions, allocating resources, and planning and forecasting for future periods.

The following table presents information about reported segment revenue, segment loss, and significant segment expenses as provided to the CODM with respect to the Company’s single operating segment for the years ended December 31, 2024, 2023 and 2022:

 

Year Ended December 31,

 

 

2024

 

 

2023

 

 

2022

 

Revenue

$

781,367

 

 

$

396,591

 

 

$

75,422

 

Less:

 

 

 

 

 

 

 

 

Internal research and development costs

 

91,881

 

 

 

121,931

 

 

 

116,525

 

Internal selling, general and administrative costs

 

162,874

 

 

 

176,778

 

 

 

99,750

 

External commercial costs

 

229,991

 

 

 

230,166

 

 

 

103,229

 

External research and development costs

 

194,422

 

 

 

186,812

 

 

 

228,659

 

External general and administrative costs

 

35,327

 

 

 

33,570

 

 

 

25,151

 

Other segment items (1)

 

121,842

 

 

 

59,238

 

 

 

38,814

 

Share-based compensation expense

 

114,128

 

 

 

105,945

 

 

 

91,085

 

Interest income

 

(12,773

)

 

 

(20,933

)

 

 

(8,914

)

Interest expense

 

40,391

 

 

 

29,581

 

 

 

32,626

 

Income tax expense

 

1,162

 

 

 

2,132

 

 

 

669

 

Net loss

$

(197,878

)

 

$

(528,629

)

 

$

(652,172

)

 

(1)
Other segment items include cost of sales, loss on conversion of debt, and other expenses.