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Product Revenues, Accounts Receivable, and Reserves for Product Sales - Schedule of Factoring of Accounts Receivable and Associated Fees (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2024 USD ($)
Product Revenues Accounts Receivable And Reserves For Product Sales [Abstract]
Accounts receivable sold	$ 142,698
Less: factoring fees	(1,700)
Net cash proceeds	$ 140,998

X

- Definition

Payment of factoring fees.

+ References

No definition available.

+ Details

Name:	apls_PaymentOfFactoringFees
Namespace Prefix:	apls_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

X

- Definition

Proceeds from sale of other receivables net of factoring fees.

+ References

No definition available.

+ Details

Name:	apls_ProceedsFromSaleOfOtherReceivablesNetOfFactoringFees
Namespace Prefix:	apls_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

Product revenues, accounts receivable, and reserves for product sales.

+ References

No definition available.

+ Details

Name:	apls_ProductRevenuesAccountsReceivableAndReservesForProductSalesAbstract
Namespace Prefix:	apls_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Amount of cash inflow from the sale of receivables classified as other.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 12
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482740/230-10-45-12

+ Details

Name:	us-gaap_ProceedsFromSaleOfOtherReceivables
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration