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Segment Information - Schedule of Segment Revenue, Segment Profit or Loss and Significant Segment Expenses (Detail) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Less:      
Interest income $ (12,773) $ (20,933) $ (8,914)
Interest expense 40,391 29,581 32,626
Income tax expense 1,162 2,132 669
Net Income (Loss) (197,878) (528,628) (652,172)
Reported Segment [Member]      
Segment Reporting Information [Line Items]      
Revenue 781,367 396,591 75,422
Less:      
Internal research and development costs 91,881 121,931 116,525
Internal selling, general and administrative costs 162,874 176,778 99,750
External commercial costs 229,991 230,166 103,229
External research and development costs 194,422 186,812 228,659
External general and administrative costs 35,327 33,570 25,151
Other segment items [1] 121,842 59,238 38,814
Share-based compensation expense 114,128 105,945 91,085
Interest income 12,773 20,933 8,914
Interest expense 40,391 29,581 32,626
Income tax expense 1,162 2,132 669
Net Income (Loss) $ (197,878) $ (528,629) $ (652,172)
[1] Other segment items include cost of sales, loss on conversion of debt, and other expenses.