    <SEC-DOCUMENT>0000950170-25-056968-index.html : 20250423
    <SEC-HEADER>0000950170-25-056968.hdr.sgml : 20250423
    <ACCEPTANCE-DATETIME>20250423073655
    ACCESSION NUMBER:		0000950170-25-056968
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20241231
    FILED AS OF DATE:		20250423
    DATE AS OF CHANGE:		20250423
    EFFECTIVENESS DATE:		20250423

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Apellis Pharmaceuticals, Inc.
    		CENTRAL INDEX KEY:			0001492422
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				271537290
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-38276
    		FILM NUMBER:		25859224

    	BUSINESS ADDRESS:
    		STREET 1:		100 FIFTH AVENUE
    		CITY:			WALTHAM
    		STATE:			MA
    		ZIP:			02451
    		BUSINESS PHONE:		617-977-5700

    	MAIL ADDRESS:
    		STREET 1:		100 FIFTH AVENUE
    		CITY:			WALTHAM
    		STATE:			MA
    		ZIP:			02451
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>apls-2025_-ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: apls-2025_-ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>