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v3.25.2

Segment Information - Schedule of Segment Revenue, Segment Profit or Loss and Significant Segment Expenses (Detail) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Mar. 31, 2025 | Jun. 30, 2024 | Mar. 31, 2024 | Jun. 30, 2025 | Jun. 30, 2024
Less: |  |  |  |  |  |  |
Interest income |  | $ (2,607) |  | $ (3,184) |  | $ (5,265) | $ (6,488)
Interest expense |  | 11,152 |  | 9,359 |  | 22,201 | 16,326
Income tax expense |  | 466 |  | 114 |  | 807 | 284
Net loss |  | (42,151) | $ (92,225) | (37,657) | $ (66,423) | (134,376) | (104,080)
Reported Segment [Member] |  |  |  |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |  |  |  |
Revenue |  | 178,494 |  | 199,685 |  | 345,291 | 372,009
Less: |  |  |  |  |  |  |
Internal research and development costs |  | 21,692 |  | 21,143 |  | 44,642 | 40,867
Internal selling, general and administrative costs |  | 43,527 |  | 43,788 |  | 90,194 | 90,128
External commercial costs |  | 60,081 |  | 59,207 |  | 117,074 | 117,879
External research and development costs |  | 33,871 |  | 43,163 |  | 85,590 | 94,154
External general and administrative costs |  | 11,787 |  | 8,738 |  | 21,846 | 16,867
Other segment items | [1] | 13,479 |  | 25,024 |  | 48,007 | 45,733
Share-based compensation expense |  | 27,197 |  | 29,990 |  | 54,571 | 60,339
Interest income |  | (2,607) |  | (3,184) |  | (5,265) | (6,488)
Interest expense |  | 11,152 |  | 9,359 |  | 22,201 | 16,326
Income tax expense |  | 466 |  | 114 |  | 807 | 284
Net loss |  | $ (42,151) |  | $ (37,657) |  | $ (134,376) | $ (104,080)
[1] | Other segment items include cost of sales and other expenses.

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