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Subsequent Events - Additional Information (Details) - Swedish Orphan Biovitrum AB (Publ) [Member] - Subsequent Event [Member] $ in Millions | Jul. 01, 2025 USD ($)
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Royalty Agreement [Member] |
Subsequent Event [Line Items] |
Upfront payment to be received | $ 275.0
Aggregate amount agreed to be received upon European Medicines Agency approval | $ 25.0
Collaboration and License Agreement [Member] |
Subsequent Event [Line Items] |
Percentage of royalty payment obligation | 90.00%
Percentage of royalty payment obligation reverted | 100.00%

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- Definition Aggregate amount agreed to be received upon agency approval. + References No definition available. + Details
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Namespace Prefix: | apls_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Percentage of royalty payment obligation. + References No definition available. + Details
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Namespace Prefix: | apls_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

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- Definition Percentage of royalty payment obligation reverted. + References No definition available. + Details
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Namespace Prefix: | apls_
Data Type: | dtr-types:percentItemType
Balance Type: | na
Period Type: | instant

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- Definition Upfront payment to be received. + References No definition available. + Details
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Namespace Prefix: | apls_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | instant

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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 830 -SubTopic 30 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147481674/830-30-50-2 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 855 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147483399/855-10-50-2 + Details
Name: | us-gaap_SubsequentEventLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

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- Details
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Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | srt_CounterpartyNameAxis=apls_SwedishOrphanBiovitrumABPublMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_SubsequentEventTypeAxis=us-gaap_SubsequentEventMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

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- Details
Name: | us-gaap_TypeOfArrangementAxis=apls_CollaborationAndLicenseAgreementMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |