XML 42 R34.htm IDEA: XBRL DOCUMENT
v3.25.3

Product Revenues, Accounts Receivable, and Reserves for Product Sales - Summary of Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Sep. 30, 2025 | Jun. 30, 2025 | Mar. 31, 2025 | Sep. 30, 2024 | Jun. 30, 2024 | Mar. 31, 2024
Fees And Patient Assistance [Member] |  |  |  |  |  |
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward] |  |  |  |  |  |
Beginning Balance | $ 10,460 | $ 9,221 | $ 11,589 | $ 5,930 | $ 5,671 | $ 5,674
Provision related to sales in the current period | 12,695 | 12,138 | 10,277 | 11,455 | 10,025 | 9,575
Adjustments related to prior period sales | 366 | (66) | 439 | 2,332 | (131) | 146
Credits and payments made | (12,436) | (10,833) | (13,084) | (12,078) | (9,635) | (9,724)
Ending balance | 11,085 | 10,460 | 9,221 | 7,639 | 5,930 | 5,671
Government and Other Rebates [Member] |  |  |  |  |  |
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward] |  |  |  |  |  |
Beginning Balance | 30,577 | 27,192 | 31,533 | 15,589 | 12,098 | 8,898
Provision related to sales in the current period | 38,426 | 30,823 | 24,139 | 25,364 | 17,777 | 13,125
Adjustments related to prior period sales | (12) | 185 | (13) | 420 | 354 | (19)
Credits and payments made | (34,730) | (27,623) | (28,467) | (17,695) | (14,640) | (9,906)
Ending balance | 34,261 | 30,577 | 27,192 | 23,678 | 15,589 | 12,098
Returns [Member] |  |  |  |  |  |
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward] |  |  |  |  |  |
Beginning Balance | 3,485 | 2,491 | 2,023 | 1,183 | 1,453 | 2,053
Provision related to sales in the current period | 1,152 | 1,083 | 976 | 1,380 | 1,039 | 1,355
Adjustments related to prior period sales | (211) | 852 | (382) | 0 | (983) | (96)
Credits and payments made | (2,324) | (941) | (126) | (979) | (326) | (1,859)
Ending balance | 2,102 | 3,485 | 2,491 | 1,584 | 1,183 | 1,453
Product Revenue Allowance and Reserves [Member] |  |  |  |  |  |
SEC Schedule, 12-09, Movement in Valuation Allowances and Reserves [Roll Forward] |  |  |  |  |  |
Beginning Balance | 44,522 | 38,904 | 45,145 | 22,702 | 19,222 | 16,625
Provision related to sales in the current period | 52,273 | 44,044 | 35,392 | 38,199 | 28,841 | 24,055
Adjustments related to prior period sales | 143 | 971 | 44 | 2,752 | (760) | 31
Credits and payments made | (49,490) | (39,397) | (41,677) | (30,752) | (24,601) | (21,489)
Ending balance | $ 47,448 | $ 44,522 | $ 38,904 | $ 32,901 | $ 22,702 | $ 19,222

X
- Definition Product revenue allowances and reserves. + References No definition available. + Details
Name: | apls_ProductRevenueAllowancesAndReserves
Namespace Prefix: | apls_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | instant

X
- Definition Product revenue allowances and reserves, adjustments related to prior period sales. + References No definition available. + Details
Name: | apls_ProductRevenueAllowancesAndReservesAdjustmentsRelatedToPriorPeriodSales
Namespace Prefix: | apls_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition Product revenue allowances and reserves, credit and payments made. + References No definition available. + Details
Name: | apls_ProductRevenueAllowancesAndReservesCreditAndPaymentsMade
Namespace Prefix: | apls_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

X
- Definition Product revenue allowances and reserves, provision related to sales in the current year. + References No definition available. + Details
Name: | apls_ProductRevenueAllowancesAndReservesProvisionRelatedToSalesInTheCurrentYear
Namespace Prefix: | apls_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration

X
- Definition A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period. + References No definition available. + Details
Name: | us-gaap_MovementInValuationAllowancesAndReservesRollForward
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Details
Name: | us-gaap_ValuationAllowancesAndReservesTypeAxis=apls_FeesAndPatientAssistanceMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ValuationAllowancesAndReservesTypeAxis=apls_AllowanceForGovernmentAndOtherRebatesMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ValuationAllowancesAndReservesTypeAxis=us-gaap_SalesReturnsAndAllowancesMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | us-gaap_ValuationAllowancesAndReservesTypeAxis=apls_ProductRevenueAllowanceAndReservesMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |