XML 16 R8.htm IDEA: XBRL DOCUMENT
v3.25.3

Insider Trading Arrangements | 3 Months Ended
--- | ---
Sep. 30, 2025 shares
Trading Arrangements, by Individual |
Material Terms of Trading Arrangement | The following table describes, for the quarterly period covered by this report, each trading arrangement for the sale or purchase of our securities adopted or terminated by our directors and officers that is either (1) a contract, instruction or written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c), or a Rule 10b5-1 trading arrangement, or (2) a “non-Rule 10b5-1 trading arrangement” (as defined in Item 408(c) of Regulation S-K):
Name (Title) |  | Action Taken (Date of Action) |  | Type of Trading Arrangement |  | Nature of Trading Arrangement |  | Duration of Trading Arrangement |  |  | Aggregate Number of Securities |
Cedric G Francois President and Chief Executive Officer |  | Termination 8/14/2025 |  | Rule 10b5-1 trading arrangement |  | Sale |  |  | (1 | ) |  |  | (1 | )
Caroline Baumal Chief Medical Officer |  | Adoption 8/19/2025 |  | Rule 10b5-1 trading arrangement |  | Sale |  | Until 2/27/2027, or such earlier date upon which all transactions are completed or expire without execution |  |  | Up to 14,698 shares |
James Chopas Vice President, Corporate Controller and Chief Accounting Officer |  | Adoption 9/15/2025 |  | Rule 10b5-1 trading arrangement |  | Sale |  | Until 1/29/2027, or such earlier date upon which all transactions are completed or expire without execution |  |  | Up to 25,947 shares |
(1) This trading plan related to 358,090 shares of our common stock and had a scheduled expiration date of 7/31/2025.
Cedric G Francois [Member] |
Trading Arrangements, by Individual |
Name | Cedric G Francois
Title | President and Chief ExecutiveOfficer
Rule 10b5-1 Arrangement Terminated | true
Termination Date | 8/14/2025
Expiration Date | 7/31/2025
Aggregate Available | 358,090
Caroline Baumal [Member] |
Trading Arrangements, by Individual |
Name | Caroline Baumal
Title | Chief Medical Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | 8/19/2025
Expiration Date | 2/27/2027
Aggregate Available | 14,698
James Chopas [Member] |
Trading Arrangements, by Individual |
Name | James Chopas
Title | Vice President, Corporate Controller andChief Accounting Officer
Rule 10b5-1 Arrangement Adopted | true
Adoption Date | 9/15/2025
Expiration Date | 1/29/2027
Aggregate Available | 25,947

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 1 + Details
Name: | ecd_MtrlTermsOfTrdArrTextBlock
Namespace Prefix: | ecd_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 1 + Details
Name: | ecd_Rule10b51ArrAdoptedFlag
Namespace Prefix: | ecd_
Data Type: | xbrli:booleanItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 1 + Details
Name: | ecd_Rule10b51ArrTrmntdFlag
Namespace Prefix: | ecd_
Data Type: | xbrli:booleanItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph A + Details
Name: | ecd_TradingArrByIndTable
Namespace Prefix: | ecd_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph B + Details
Name: | ecd_TrdArrAdoptionDate
Namespace Prefix: | ecd_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph C + Details
Name: | ecd_TrdArrExpirationDate
Namespace Prefix: | ecd_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph A + Details
Name: | ecd_TrdArrIndName
Namespace Prefix: | ecd_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph A + Details
Name: | ecd_TrdArrIndTitle
Namespace Prefix: | ecd_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph D + Details
Name: | ecd_TrdArrSecuritiesAggAvailAmt
Namespace Prefix: | ecd_
Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | instant

X
- References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-K -Number 229 -Section 408 -Subsection a -Paragraph 2 -Subparagraph B + Details
Name: | ecd_TrdArrTerminationDate
Namespace Prefix: | ecd_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration

X
- Details
Name: | ecd_IndividualAxis=apls_CedricGFrancoisMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | ecd_IndividualAxis=apls_CarolineBaumalMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |

X
- Details
Name: | ecd_IndividualAxis=apls_JamesChopasMember
Namespace Prefix: |
Data Type: | na
Balance Type: |
Period Type: |