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Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands | Sep. 30, 2025 | Dec. 31, 2024
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Payables and Accruals [Abstract] |  |
Accrued research and development | $ 17,525 | $ 22,782
Accrued royalties | 7,059 | 7,147
Accrued payroll liabilities | 32,542 | 40,888
Accrued goods received not invoiced | 3,498 | 638
Product revenue reserves | 47,448 | 45,145
Commercial costs | 27,588 | 20,610
Other | 4,662 | 2,974
Total accrued expenses | $ 140,322 | $ 140,184

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