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Nature of Organization and Operations - Additional Information (Detail) - USD ($) $ in Thousands	Sep. 30, 2025	Dec. 31, 2024	Sep. 30, 2024
Nature Of Organization And Operations [Line Items]
Cash and cash equivalents	$ 479,171	$ 411,290	$ 396,864
Accumulated deficit	$ (2,954,027)	$ (3,035,366)

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Nature of organization and operations.

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Amount of cash and cash equivalent. Cash includes, but is not limited to, currency on hand, demand deposit with financial institution, and account with general characteristic of demand deposit. Cash equivalent includes, but is not limited to, short-term, highly liquid investment that is both readily convertible to known amount of cash and so near maturity that it presents insignificant risk of change in value because of change in interest rate.

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Amount of accumulated undistributed earnings (deficit).

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