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Product Revenues, Accounts Receivable, and Reserves for Product Sales - Schedule of Factoring of Accounts Receivable and Associated Fees (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Revenue, Major Customer [Line Items]
Accounts receivable sold	$ 0	$ 56,590	$ 199,448	$ 56,590
Less: factoring fees	0	(672)	(2,433)	(672)
Net cash proceeds	$ 0	$ 55,918	$ 197,015	$ 55,918

X

- Definition

Payment of factoring fees.

+ References

No definition available.

+ Details

Name:	apls_PaymentOfFactoringFees
Namespace Prefix:	apls_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

X

- Definition

Proceeds from sale of other receivables net of factoring fees.

+ References

No definition available.

+ Details

Name:	apls_ProceedsFromSaleOfOtherReceivablesNetOfFactoringFees
Namespace Prefix:	apls_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

Name:	us-gaap_EntityWideRevenueMajorCustomerLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Amount of cash inflow from the sale of receivables classified as other.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 12
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482740/230-10-45-12

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration