<SEC-DOCUMENT>0000902219-25-000121.txt : 20250210
<SEC-HEADER>0000902219-25-000121.hdr.sgml : 20250210
<ACCEPTANCE-DATETIME>20250210104927
ACCESSION NUMBER:		0000902219-25-000121
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20250210
DATE AS OF CHANGE:		20250210

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Apellis Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001492422
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				271537290
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-90187
		FILM NUMBER:		25604306

	BUSINESS ADDRESS:	
		STREET 1:		100 FIFTH AVENUE
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451
		BUSINESS PHONE:		617-977-5700

	MAIL ADDRESS:	
		STREET 1:		100 FIFTH AVENUE
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			WELLINGTON MANAGEMENT GROUP LLP
		CENTRAL INDEX KEY:			0000902219
		STANDARD INDUSTRIAL CLASSIFICATION:	UNKNOWN SIC - 0000 [0000]
		ORGANIZATION NAME:           	
		IRS NUMBER:				042683227
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		C/O WELLINGTON MANAGEMENT COMPANY LLP
		STREET 2:		280 CONGRESS STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
		BUSINESS PHONE:		6179515000

	MAIL ADDRESS:	
		STREET 1:		C/O WELLINGTON MANAGEMENT COMPANY LLP
		STREET 2:		280 CONGRESS STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	WELLINGTON MANAGEMENT CO LLP
		DATE OF NAME CHANGE:	19960930

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	WELLINGTON MANAGEMENT CO
		DATE OF NAME CHANGE:	19930426
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0000902219-20-000229</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0000902219</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>8</amendmentNo>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2024</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001492422</issuerCik>
        <issuerName>Apellis Pharmaceuticals, Inc.</issuerName>
        <issuerCusip>03753U106</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>100 5th Avenue</com:street1>
          <com:city>Waltham</com:city>
          <com:stateOrCountry>X1</com:stateOrCountry>
          <com:zipCode>02451</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Wellington Management Group LLP</reportingPersonName>
      <citizenshipOrOrganization>MA</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>11418239</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>11833409</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>11833409.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.5</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Wellington Group Holdings LLP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>11418239</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>11833409</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>11833409.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.5</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Wellington Investment Advisors Holdings LLP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>11418239</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>11833409</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>11833409.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.5</classPercent>
      <typeOfReportingPerson>HC</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Wellington Management Company LLP</reportingPersonName>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>11382754</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>11603969</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>11833409.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.3</classPercent>
      <typeOfReportingPerson>IA</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Apellis Pharmaceuticals, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>100 5th Avenue, Waltham MA 02451</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>
Wellington Management Group LLP
Wellington Group Holdings LLP
Wellington Investment Advisors Holdings LLP
Wellington Management Company LLP
</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>c/o Wellington Management Company LLP, 280 Congress Street, Boston MA 02210</principalBusinessOfficeOrResidenceAddress>
        <citizenship>
Wellington Management Group LLP - Massachusetts
Wellington Group Holdings LLP - Delaware
Wellington Investment Advisors Holdings LLP - Delaware
Wellington Management Company LLP - Delaware</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>HC</typeOfPersonFiling>
        <typeOfPersonFiling>IA</typeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>See the responses to Item 9 on the attached cover pages.</amountBeneficiallyOwned>
        <classPercent>9.51</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>0</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>See the responses to Item 6 on the attached cover pages.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>See the responses to Item 8 on the attached cover pages.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>N</notApplicableFlag>
        <ownershipMoreThan5PercentOnBehalfOfAnotherPerson>The securities as to which this Schedule is filed are owned of record by clients of one or more investment advisers identified in Item 7 directly or indirectly owned by Wellington Management Group LLP. Those clients have the right to receive, or the power to direct the receipt of, dividends from, or the proceeds from the sale of, such securities. No such client is known to have such right or power with respect to more than five percent of this class of securities, except as follows:

Vanguard Health Care Fund</ownershipMoreThan5PercentOnBehalfOfAnotherPerson>
      </item6>
      <item7>
        <notApplicableFlag>N</notApplicableFlag>
        <subsidiaryIdentificationAndClassification>
Pursuant to the instructions in Item 7 of Schedule 13G, the following lists the identity and Item 3 classification of each relevant entity that beneficially owns shares of the security class being reported on this Schedule 13G.

    Wellington Group Holdings LLP - HC
    Wellington Investment Advisors LLP - HC
    Wellington Management Global Holdings, Ltd. - HC

One or more of the following investment advisers (the "Wellington Investment Advisers"):

    Wellington Management Company LLP - IA
    Wellington Management Canada LLC - IA
    Wellington Management Singapore Pte Ltd - IA
    Wellington Management Hong Kong Ltd - IA
    Wellington Management International Ltd - IA
    Wellington Management Japan Pte Ltd - IA
    Wellington Management Australia Pty Ltd - IA

The securities as to which this Schedule is filed by Wellington Management Group LLP, as parent holding company of certain holding companies and the Wellington Investment Advisers, are owned of record by clients of the Wellington Investment Advisers. Wellington Investment Advisors Holdings LLP controls directly, or indirectly through Wellington Management Global Holdings, Ltd., the Wellington Investment Advisers. Wellington Investment Advisors Holdings LLP is owned by Wellington Group Holdings LLP. Wellington Group Holdings LLP is owned by Wellington Management Group LLP.
</subsidiaryIdentificationAndClassification>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Wellington Management Group LLP</reportingPersonName>
      <signatureDetails>
        <signature>Taisia Lowe</signature>
        <title>Regulatory Analyst</title>
        <date>02/10/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Wellington Group Holdings LLP</reportingPersonName>
      <signatureDetails>
        <signature>Taisia Lowe</signature>
        <title>Regulatory Analyst</title>
        <date>02/10/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Wellington Investment Advisors Holdings LLP</reportingPersonName>
      <signatureDetails>
        <signature>Taisia Lowe</signature>
        <title>Regulatory Analyst</title>
        <date>02/10/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Wellington Management Company LLP</reportingPersonName>
      <signatureDetails>
        <signature>Taisia Lowe</signature>
        <title>Regulatory Analyst</title>
        <date>02/10/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>

</edgarSubmission>
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</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>2
<FILENAME>Rule13D_JointFilingAgreement.htm
<DESCRIPTION>JOINT FILING AGREEMENT
<TEXT>






<html>
	<head>
		<title>Wellington Joint Filing Agreement</title>
	</head>
	<body>




		<div align="center">
			<p>
<h4 align="center"><u>JOINT FILING AGREEMENT</u></h4>
			</p>
    </div>

 <table>
    <tr>
        <td width="10%"> </td>
        <td>
The undersigned hereby agree that this Schedule 13G (the &#x201C;Schedule 13G&#x201D;)
with respect to the common stock of Apellis Pharmaceuticals, Inc. is,
and any additional
amendment thereto signed by each of the undersigned shall be, filed on
behalf of each undersigned pursuant to and in accordance with the
provisions of 13d-1(k) under the Securities Exchange Act of 1934,
as amended, and that all subsequent amendments to the Schedule 13G
shall be filed on behalf of each of the undersigned without the necessity
of filing additional joint filing agreements. The undersigned acknowledge
that each shall be responsible for the timely filing of such amendments,
and for the completeness and accuracy of the information concerning it
contained therein, but shall not be responsible for the completeness and
accuracy of the information concerning the other, except to the extent that
it knows or has reason to believe that such information is inaccurate. It is
understood and agreed that the joint filing of the Schedule 13G shall not be
construed as an admission that the persons named herein constitute a group for
purposes of Regulation 13D-G of the Securities Exchange Act of 1934, nor is a
joint venture for purposes of the Investment Company Act of 1940.
<br /><br />
        </td>
        <td width="10%"> </td>
    </tr>
   </table>


<table>






    <tr>
        <td width="50%"> </td>
        <td>
By:  Wellington Management Group LLP<br />
        </td>
    </tr>









    <tr>
        <td width="50%"> </td>
        <td>
By:  <u>/s/ Taisia Lowe</u><br />
        </td>
    </tr>

    <tr>
        <td width="50%"> </td>
        <td>
Name:    Taisia Lowe<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Title:   Regulatory Analyst<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Date:    February 10,2025<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
<br />
        </td>
    </tr>

<br />







    <tr>
        <td width="50%"> </td>
        <td>
By:
Wellington Group Holdings LLP<br />
        </td>
    </tr>









    <tr>
        <td width="50%"> </td>
        <td>
By:  <u>/s/
Taisia Lowe</u><br />
        </td>
    </tr>

    <tr>
        <td width="50%"> </td>
        <td>
Name:
Taisia Lowe<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Title:
Regulatory Analyst<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Date:    February 10,2025<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
<br />
        </td>
    </tr>






    <tr>
        <td width="50%"> </td>
        <td>
By:
Wellington Investment Advisors Holdings LLP<br />
        </td>
    </tr>









    <tr>
        <td width="50%"> </td>
        <td>
By:  <u>/s/
Taisia Lowe</u><br />
        </td>
    </tr>

    <tr>
        <td width="50%"> </td>
        <td>
Name:
Taisia Lowe<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Title:
Regulatory Analyst<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Date:    February 10,2025<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
<br />
        </td>
    </tr>






    <tr>
        <td width="50%"> </td>
        <td>
By:
Wellington Management Company LLP<br />
        </td>
    </tr>









    <tr>
        <td width="50%"> </td>
        <td>
By:  <u>/s/
Taisia Lowe</u><br />
        </td>
    </tr>

    <tr>
        <td width="50%"> </td>
        <td>
Name:
Taisia Lowe<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Title:
Regulatory Analyst<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
Date:    February 10,2025<br />
        </td>
    </tr>
    <tr>
        <td width="50%"> </td>
        <td>
<br />
        </td>
    </tr>


</table>



  </body>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
