EX-99.2 3 d924731dex992.htm EX-99.2

Nasdaq SFNC Exhibit 99.2 nd 2 Quarter 2025 Earnings Presentation July 17, 2025

Company Overview Simmons First National Corporation A Mid-South based financial holding company serving our $26.7 $21.8 customers and the communities where we work and live since 1903 BILLION BILLION TOTAL ASSETS TOTAL DEPOSITS $8.9 $17.1 CONSECUTIVE YEARS 3 116 PAYING DIVIDENDS BILLION BILLION ASSETS UNDER TOTAL LOANS MANAGEMENT/ ADMINISTRATION YEARS OF SERVICE 122 14.4% 8.5% 1 TOTAL RBC RATIO TCE RATIO FINANCIAL CENTERS 223 ACROSS SIX STATES 4.2% 78% 2 DIVIDEND YIELD LOAN TO DEPOSIT RATIO 1.48% 161% ACL TO TOTAL NPL COVERAGE LOANS RATIO Figures presented on this slide are as of June 30, 2025, unless otherwise noted 2 1 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations 2 Based on July 10, 2025, closing stock price of $20.19 and annualized dividend rate of $0.85 per share 3 The future payment of dividends is not guaranteed and is subject to various factors, including approval by the Company’s board of directors

2Q25 Financial Highlights 3

2Q25 Highlights ❑ Strong top-line growth drives performance 1 Reported Adjusted 1 1 ─ Adjusted net income of $56.1 million and adjusted diluted EPS of $0.44 ─ Net interest margin surpasses 3% mark ahead of expectations Net income $54.8M $56.1M • Net interest margin at 3.06%, up 11 bps linked quarter and 37 bps year-over-year th • 5 consecutive quarterly increase in net interest margin • Pricing discipline leads to 6 bps increase in loan yields linked quarter EPS (diluted) $0.43 $0.44 rd • Cost of deposits decline for 3 consecutive quarter, down 8 bps vs 1Q25 1 ─ Total revenue tops $214 million and adjusted PPNR totaled $77.3 million Revenue $214.2M $214.2M • Net interest income up $8.4 million, or 5%, on a linked quarter basis 1 • Adjusted noninterest expense was $136.8 million , down 5% vs 1Q25 2 PPNR $75.6M $77.3M ❑ Positive underlying balance sheet momentum ─ Total loans at $17.0 billion, up slightly on a linked quarter basis • Average loans at $17.0 billion, up 3% on a linked quarter annualized basis NIM 3.06% • Linked quarter growth driven by C&I, agricultural, and consumer & other portfolios rd • Unfunded commitments rose for 3 consecutive quarter NCO ratio 25 bps ─ Total deposits at $21.8 billion, up 1% linked quarter • Low-cost customer deposits increase $233.1 million vs 1Q25 ACL ratio 1.48% ❑ Credit quality remains healthy ‒ Net charge offs at 25 bps in 2Q25; provision expense exceeded net charge-offs NPL/Loans 92 bps ‒ ACL ratio at 1.48%, unchanged from 1Q25 levels Comparisons on this page are 2Q25 vs 1Q25, unless otherwise noted Bps = basis points 1 Non-GAAP measures that management believes aid in the discussion of results. See Appendix for Non-GAAP reconciliations 4 2 All pre-provision net revenue (PPNR) figures set forth in this row are Non-GAAP measures. See footnote 1 for more information

Balance Sheet Highlights Average Investment Securities Average Loans Average Deposits $ in billions $ in billions $ in billions $22.0 $21.7 $21.7 $21.9 $21.4 $17.2 $17.2 $6.6 $17.1 $17.0 $17.4 $17.4 $17.2 $17.3 $17.0 $6.4 $16.9 $6.3 $6.1 $6.0 $4.6 $4.5 $4.5 $4.3 $4.4 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 Noninterest Bearing Interest Bearing 1 1 6.32% 6.20% Yield 6.39% 6.44% 6.26% Yield Cost 2.79% 3.68% 3.63% 3.54% 3.48% 3.48% 2.79% 2.60% 2.44% 2.36% Investment Securities Loans Deposits $ in billions; Period End Balances $ in billions; Period End Balances $ in billions; Period End Balances $21.9 $21.8 $21.9 $21.8 $21.7 $17.3 $17.2 $17.1 $17.1 $6.6 $17.2 $17.4 $17.4 $17.2 $17.4 $17.0 $6.3 $6.2 $6.1 $6.0 $4.6 $4.5 $4.5 $4.5 $4.5 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 Noninterest Bearing Interest Bearing 1 Yield is presented on a fully taxable equivalent (FTE) basis using an effective tax rate of 26.135% 5

Income Statement Highlights 2 2 2 Net Interest Income Total Revenue and Adjusted Total Revenue PPNR and Adjusted PPNR $ in millions $ in millions $ in millions $214.2 $214.2 $77.3 $209.6 $208.5 $208.5 $209.6 $75.6 $171.8 $203.2 $69.2 $66.4 $66.0 $67.4 $65.0 $164.9 $174.8 $163.4 $157.7 $37.6 3Q24 4Q24 1Q25 2Q25 3Q24 4Q24 1Q25 2Q25 3Q24 4Q24 1Q25 2Q25 Total Revenue Adjusted Revenue2 PPNR2 Adjusted PPNR2 1 NIM 2.74% 3.06% 2.87% 2.95% 2 2 2 NIE and Adjusted NIE Net Income and Adjusted Net Income Diluted EPS and Adjusted Diluted EPS $ in millions $ in millions $144.6 $0.44 $0.43 $143.6 $56.1 $54.8 $0.39 $0.38 $49.6 $0.37 $141.1 $48.3 $46.0 $139.3 $138.6 $137.2 $136.8 $33.1 $136.8 $32.4 $0.26 $0.26 $24.7 $0.20 3Q24 4Q24 1Q25 2Q25 3Q24 4Q24 1Q25 2Q25 3Q24 4Q24 1Q25 2Q25 Noninterest Expense Adjusted Noninterest Expense2 Net Income Adjusted Net Income2 Diluted EPS Adjusted Diluted EPS2 PPNR – Pre-provision net revenue NIE – Noninterest Expense 6 EPS – Earnings per Share 1 Net interest margin (NIM) is presented on a fully taxable equivalent (FTE) basis using an effective tax rate of 26.135% 2 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations

Net Interest Margin (FTE) Net Interest Margin Net Interest Margin Evolution FTE (%) FTE 2 bps 3.06% 4 bps +37 bps 5 bps 2.95% 3.06% Commentary 2.95% 2.87% (2Q25 vs 1Q25) +11 bps 2.74% 2.69% ❑ Expansion primarily driven by fixed-rate asset repricing coupled with decreased deposit costs from lower rates on time deposits and favorable funding mix shift ❑ NIM surpasses 3% mark ahead of expectations 1Q25 Funding Loan 2Q25 Other Rate Yield ▪ NIM at 3.06 percent, up 11 bps 2Q24 3Q24 4Q24 1Q25 2Q25 th ▪ 5 consecutive quarter of NIM expansion ❑ Reflects focus on maintaining loan pricing discipline and continued proactive deposit pricing management ▪ 6 bps increase in loan yields ▪ 8 bps decrease on cost of deposits 1 Estimated Future Swap Income Select Yields/Rates $ in millions; Based on Forward Fed Funds rates ❑ $37M of 6% subordinated debt from Spirit of Texas FTE (%) acquisition to be called on 7/31/25 6.39 6.44 6.32 6.20 6.26 Assumed Average Effective Fed Funds Rate ❑ Remaining balance of purchase accounting accretion at 5.84 4.20% 3.95% 3.64% 3.42% 3.23% 5.79 6/30/25 was $4.8 million 5.32 5.09 4.97 3.68 3.63 3.54 3.48 3.48 $7.7 $7.1 $6.2 $5.6 $5.3 2.79 2.79 2.60 2.44 2.36 2Q24 3Q24 4Q24 1Q25 2Q25 Loan Yield (FTE) Securities (FTE) 3Q25 4Q25 1Q26 2Q26 3Q26 Cost of Deposits Other Borrowings FTE – Fully taxable equivalent using an effective tax rate of 26.135% Totals may not foot due to rounding 7 1 Estimated swap income based on projected forward effective fed funds rates as of June 30, 2025. Does not include potential impact of hedge ineffectiveness that is recorded in interest income. Under the terms of the swap agreement, the Company receives Effective Fed Funds rate and pays a fixed rate of approximately 1.21%

Noninterest Income 2Q25 Adjusted 2Q25 vs Adjusted 1 $ in millions 1Q25 2Q24 Reported Adjusted Service charges on deposit accounts $ 12.6 $ 12.6 $ - - % $ 0.3 3 % Commentary Wealth management fees 9 .5 9.5 ( 0.2) (2) 0.3 3 ❑ Overall fee levels in-line with management Debit and credit card fees 8.6 8.6 0 .1 1 0.4 5 expectations following strong performance in 1Q25 Mortgage lending income 1 .7 1.7 ( 0.3) (16) ( 0.3) (14) ❑ Linked quarter decrease in swap fee income due Bank owned life insurance 3 .9 3.9 ( 0.2) ( 5) - - to large swap transaction recorded in 1Q25 Swap fee income 0.8 0.8 ( 0.6) (41) 0.2 30 ❑ Linked quarter decrease in “Other” noninterest income primarily driven by $1.4M SBIC valuation Other service charges and fees 1 .3 1.3 - (1) (0.1) (8) adjustment Other 4 .0 4.0 (2.6) (39) (1.8) (31) Total noninterest income $ 42.4 $ 42.4 $(3.8) ( 8) % $(0.9) (2) % Adjusted Total Revenue Per Employee Adjusted Noninterest Income Adjusted Total Revenue 1 1 1 (FTE) to Adjusted Total Revenue Per Avg. Diluted Share ($ in thousands) $1.69 $1.66 $72.7 $1.65 $71.1 $70.8 22.4% 22.0% 22.0% $1.61 $68.4 $66.6 20.9% $1.57 19.8% 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 Totals may not foot due to rounding FTE – Full-time equivalent 8 1 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations

Noninterest Expense Commentary 2Q25 Adjusted 2Q25 vs Adjusted ❑ General decrease in expenses as we focused on 1 $ in millions 1Q25 2Q24 Reported Adjusted mitigating impact of 1Q25 fraud event ▪ Implemented early retirement program Salaries and employee benefits $ 73.9 $ 72.3 ($2.6) (3) % $ 1.7 2 % ▪ Deferred or eliminated certain controllable expenses Occupancy expense, net 11.8 1 1.4 ( 0.5) ( 4) ( 0.3) (2) ▪ Benefitted from $0.7 million recovery on fraud losses Furniture and equipment 5.5 5.5 0.1 1 ( 0.2) (3) ❑ Decrease in salary and employee benefits on a Deposit insurance 4 .9 4.9 ( 0.5) ( 9) ( 0.5) (9) linked quarter basis primarily reflects a seasonal decline in payroll taxes and equity compensation OREO and foreclosure expense 0 .2 0.2 - 9 0.1 85 expense, partially offset by annual merit increase Other 42.3 4 2.5 (3.4) ( 7) ( 1.8) (4) ❑ Decrease in “Other” noninterest expense on a linked quarter basis primarily due to a $4.3 million Total noninterest expense $138.6 $136.8 ($6.8) ( 5) % $(1.0) (1) % charge related to 1Q25 fraud event Adjusted Noninterest Expense as a 1 Adjusted Efficiency Ratio Employees (FTE) # of Financial Centers 1 Percentage of Total Average Assets 234 234 65.68% 64.75% 2.18% 63.38% 62.89% 2.05% 2.06% 2.03% 223 222 222 2,972 60.52% 2,961 2.00% 2,946 2,949 2,947 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 2Q24 3Q24 4Q24 1Q25 2Q25 Note: Numbers may not add due to rounding NM – not meaningful 9 FTE – full-time equivalent 1 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations

Deposits, Securities, Liquidity, Interest Rate Sensitivity and Capital 10

Deposits Deposit Mix 1 $ in billions; Period End Balances Linked Quarter Deposit Change $ in millions; Period End Balances Low-Cost Customer $21.9 $21.9 $21.8 $21.7 $21.8 Deposits Total Deposits $140 $2.9 $3.4 $3.3 $2.9 $3.2 Noninterest Bearing Transaction Accounts $13 $2.8 $2.7 $2.8 $3.0 $2.7 +$233M $2.9 $3.4 $3.3 $3.1 $3.0 Interest Bearing Transaction and Savings Accounts $220 Time Deposits $(81) $8.0 $8.5 $8.0 $8.2 $8.3 Public Funds (interest bearing) $(336) Brokered Deposits (MM & CDs) $324 $4.6 $4.5 $4.5 $4.5 $4.5 2Q24 3Q24 4Q24 1Q25 2Q25 Noninterest Bearing Interest Bearing Transaction Accounts Time Deposits Public Funds (interest bearing) Brokered Deposits 56% interest bearing deposit Evolution of Funding Rates 2 beta since 2Q24 Interest Bearing Deposits Commentary Cost of Deposits 5.33% 5.33% 5.33% 5.26% 5.27% Avg Fed Funds Rate 4.99% ❑ Positive remix in the quarter, led by a $233 million increase in low-cost customer deposits 4.66% 4.52% 4.33% 4.33% ❑ 8 basis point decrease in cost of deposits on a linked quarter basis 3.65% 3.53% 3.52% 3.48% 3.31% 3.28% 3.06% 3.05% 2.97% ❑ Focus remains on optimizing deposit balances and proactively managing costs 2.57% 2.10% 2.79% 2.79% 2.75% ❑ ~79% of deposits are FDIC insured or are collateralized deposits 2.58% 2.60% 1.41% 2.44% 2.37% 2.36% 1.96% 1.58% 1.02% 2Q22 3Q22 4Q22 1Q23 2Q23 3Q23 4Q23 1Q24 2Q24 3Q24 4Q24 1Q25 2Q25 Source: Average Fed Funds rate based on data from www.macrotrends.net 1 Linked quarter growth is 2Q25 vs 1Q25. The categories titled “Interest Bearing Transaction Accounts” and “Time Deposits” exclude public funds and brokered deposits, which are each shown as separate categories 11 2 Deposit beta calculated as change in cost of deposits from 2Q24 to 2Q25 divided by the change in quarterly average Federal Funds Effective rate for 2Q24 vs 2Q25

Securities: Targeted mix of securities to earning assets in mid-teens 2 Securities Portfolio Summary Securities Portfolio Bond Ratings Securities Portfolio by Type $ in millions 1 8% 8% Yield (FTE) Effective Duration At June 30, 2025 At June 30, 2025 HTM AFS HTM AFS HTM AFS Fixed Rate U.S. Guaranteed/GSE $1,482 $1,400 Municipal 3.26% 3.34% 12.35 12.94 Aaa/AAA 476 287 40% MBS/CMO 2.98 1.45 6.13 4.46 44% Aa/AA 1,161 481 Treasury/Agency 2.34 3.15 8.26 0.04 A 303 80 Corporate 4.26 6.12 3.74 1.03 Baa/BBB 158 147 Other 2.49 3.49 10.04 3.76 Not Rated 16 9 Treasury/Agency States and Political Subdivisions Variable Rate - 4.84 - - Total $3,595 $2,405 MBS/CMO Corporate & Other Total 3.13% 3.12% 9.21 6.05 Fair value $2,895 $2,405 AOCI Evolution and Projections $ in millions Projected AOCI “Burn” Down AOCI Position 3 AOCI Flat Rates 6/30/24 12/31/24 6/30/25 YE YE 9/30/24 3/31/25 YE 6/30/25 2025 2027 2026 $(302) $(327) $(336) $(357) $(361) $(368) $(381) $(381) $(405) ~6% ~14% 6% ~21% FTE – fully taxable equivalent using an effective tax rate of 26.135% Data presented on this slide is as of June 30, 2025, unless otherwise noted 12 1 Effective yield of securities portfolio at 6/30/25, excluding AOCI impact of HTM transfers made during 2Q22 2 Bond ratings reflect highest rating by Moody's Investors Service, Inc., Standard & Poor's or Fitch Ratings 3 Flat Rates: projected AOCI burn down assumes interest rates remain at 6/30/25 levels, a static investment portfolio and no additional bond sales. This projection is for illustrative purposes only. See “Forward-Looking Statements and Non-GAAP Financial Measures” for more information

Liquidity: Solid liquidity position and strategic use of wholesale funding Cash and Cash Equivalents + Wholesale Funding Additional Liquidity Sources $ in millions $ in millions Variable Rate Securities $ in millions June 30, Change vs FHLB borrowing availability $ 5,133 2025 1Q25 $1,245 $1,190 $1,166 $1,145 $1,125 $1,121 Unpledged securities 3,697 Brokered deposits $3,237 $ 323 Fed Funds lines and Fed Discount Window 1,894 FF purchased/securities sold 31 (19) FHLB advances 618 (250) Total at 6.30.25 $10,724 Other 16 (1) 1 Subordinated debt 366 - 2 Uninsured, non-collateralized deposits $4,595 Total $4,268 $ 53 1Q24 2Q24 3Q24 4Q24 1Q25 2Q25 Coverage ratio 2.3x Cash & Cash Equivalents Variable Rate Securities Borrowed Funds as a Percent of Total Liabilities Loan to Deposit Ratio Period End Balances Period End Balances 12.6% 78.7% 79.0% 78.8% 78.4% 77.7% 76.1% 10.4% 10.0% 8.9% 5.9% 5.7% 5.6% 4.9% 4.5% 2018 2019 2020 2021 2022 2023 2024 1Q25 2Q25 1Q24 2Q24 3Q24 4Q24 1Q25 2Q25 1 All subordinated debt outstanding at June 30, 2025, is callable by Simmons. See Slide 7 for information about the upcoming redemption of the 6% subordinated debt from the Spirit of Texas acquisition 2 Uninsured, non-collateralized deposits represent uninsured deposits of Simmons Bank, less the uninsured portion of collateralized deposits, and deposit balances of SFNC subsidiaries. See appendix for Non-GAAP reconciliations 13

Interest Rate Sensitivity Loan Portfolio – Repricing and Maturity (contractual) CD Maturities (over the next 12 months) At June 30, 2025 $ in millions In millions Repricing Term Rate Structure Weighted Average Rates 3 mo 3-12 1-3 3-5 Over 5 Total Variable Fixed 3.91% 4.42% 3.59% 4.36% 3.46% 4.09% 2.99% 4.24% or less mo years years years RE - Construction $2 ,325.4 $ 104.6 $ 278.1 $ 65.1 $ 11.5 $ 2,784.6 $ 2,262.0 $ 522.6 $1,685.1 $1,559.4 RE - Commercial 3,001.1 823.6 2,737.4 754.2 645.1 7,961.4 3,172.8 4,788.6 RE - Single-Family 615.7 273.1 597.6 404.3 735.0 2,625.7 1,408.6 1,217.1 $980.9 $714.9 Commercial 1,521.1 120.5 414.0 285.9 99.1 2,440.5 1,589.9 850.6 $539.2 Consumer 224.5 1 5.1 40.8 1 1.2 8.3 300.0 217.4 8 2.6 $222.0 $216.5 $101.3 1 Other 582.2 39.1 48.9 42.1 286.6 9 98.9 573.3 425.6 3Q25 4Q25 1Q26 2Q26 Total $ 8,269.9 $1 ,376.0 $ 4,116.9 $ 1,562.8 $1 ,785.5 $ 17,111.1 $ 9,224.0 $7 ,887.1 Customer CDs Brokered CDs 2 7.30% 5.57% 5.26% 6.11% 4.65% 6.25% 7.05% 5.37% Weighted average rate Balance Sheet Interest Rate Sensitivity Over the next 12 months (estimated) Additional Interest Rate Sensitivity Factors 5% Higher 5% Lower Change in Interest Rates Base Case 3 ❑ ~$115 million of projected securities principal maturities per quarter Deposit Betas Deposit Betas ❑ ~$2.4 billion of projected cash flows from fixed rate loans at a weighted average Down 25 bps 0.06% 0.10% 0.03% 4 rate of 5.91% ❑ ~$0.6 billion of FHLB advances maturing at a weighted average rate of 4.49% in Down 50 bps 0.08% 0.15% 0.01% 3Q25 5 ❑ ~29% of customer interest bearing deposits are tied to index rates, principally Down 75 bps 0.13% 0.23% 0.02% Fed Funds target rate Assumes a gradual change in interest rates and static balance sheet as of June 30, 2025. Interest rate cuts in September 2025, December 2025 and March 2026 Totals may not add due to rounding 1 Other includes agriculture, mortgage warehouse and other loans 14 2 Weighted average rates do not include mortgage warehouse and credit card portfolios 3 Projections over the next 12 months assuming a static balance sheet as of June 30, 2025 4 Cash flows from fixed rate loans over the next 12 months includes prepayment assumptions and are based on the forward rate curve 5 Customer interest bearing deposits includes savings, money market, checking and customer CDs. Does not include brokered deposits

Capital: Focused on maintaining a strong capital position 1 1 1 1 CET 1 Capital Ratio Total Risk-Based Capital Ratio Tier 1 Risk-Based Capital Ratio Tier 1 Leverage Ratio 12.36% 12.36% 12.21% 12.21% 14.59% 12.00% 12.00% 14.42% 14.17% 9.96% 9.83% 9.49% 2Q24 1Q25 2Q25 2Q24 1Q25 2Q25 2Q24 1Q25 2Q25 2Q24 1Q25 2Q25 WELL CAPITALIZED WELL CAPITALIZED WELL CAPITALIZED WELL CAPITALIZED 5.0% 6.5% 8.0% 10.0% 1 1,2 Book Value Per Common Share Tangible Book Value Per Common Share Capital Ratios (at 6/30/25) Total Risk-Based Capital Ratio CET 1 Capital Ratio $16.97 $28.17 $28.04 $16.81 12.36% 14.42% $27.56 $16.20 2 Equity to Assets Tangible Common Equity Ratio 8.46% 13.30% 3 Share Repurchase Program 2Q24 1Q25 2Q25 2Q24 1Q25 2Q25❑ No shares were repurchased during the first six months of 2025 ❑ $175M remaining authorization under the current program 1 2Q25 data as of June 30, 2025, 1Q25 data as of March 31, 2025, and 2Q24 data as of June 30, 2024 2 Non-GAAP measures that management believes aid in the discussion of results. See Appendix for Non-GAAP reconciliations 15 3 Market conditions and our capital needs (among other things) will drive decisions regarding additional, future stock repurchases

Loan Portfolio 16

Loans: Well-diversified, granular portfolio and conservative credit culture Loan Portfolio Waterfall Linked Quarter Change by Loan Type $ in millions $ in millions Total Loans $17 $2,225 RE – Commercial $(90) $17,094 $40 $17,111 RE – Construction $(2,248) $7 1 Funded loans Paydowns/ Other 2 Commercial $77 /advances payoffs RE – Single Family $(21) Consumer & Other $33 Agricultural $68 Mortgage Warehouse $(47) Total loans Total loans 3 Run-Off Portfolio $(10) at 3/31/25 at 6/30/25 Unfunded Commitments $ in millions Commentary RE - Construction Commercial RE - Single Family RE - Commercial Agriculture Consumer/Other ❑ Well-diversified, granular portfolio with no significant industry or geographic concentrations $3,888 $3,947 $3,746 $3,739 $3,681 ❑ Average loans at $17.0 billion, up 3% on a linked quarter annualized basis 94% variable rate ❑ Commercial loan pipeline remains strong and unfunded commitments rose for • 62% tied to Prime 3rd consecutive quarter • 38% tied to SOFR ❑ Minimal exposure to Shared National Credits (SNC) ▪ SNC totaled ~1% of total loans 2Q24 3Q24 4Q24 1Q25 2Q25 ▪ Additional banking relationships with all borrowers 1 “Other” includes linked quarter change associated with loan portfolios impacted by seasonality (agricultural, mortgage warehouse and credit cards) and change in run-off portfolio 2 Commercial loan change excludes the impact of loans included in the run-off portfolio 17 3 “Run-off portfolio” consists of small ticket equipment finance and acquired asset based lending portfolios

Pipelines: Represent opportunities that meet pricing and disciplined credit appetite Commercial Loan Pipeline by Category $ in millions Opportunity Proposal Ready to Close $1,815 $1,631 Commentary $757 $1,265 ❑ Continued focus on maintaining prudent underwriting $1,244 $564 standards and pricing discipline $1,013 $1,002 $948 $552 $549 ❑ $564 million of ready to close loans in the commercial $249 $292 1 $330 $381 pipeline as of June 30, 2025, with a rate of 7.35% $416 $121 $168 $199 $147 ❑ Mortgage loan originations in 2Q25 $189 ❑ 83% purchase ❑ 17% refinance $343 $485 $551 $527 $514 $809 $775 4Q23 1Q24 2Q24 3Q24 4Q24 1Q25 2Q25 Rate Ready to 8.44% 8.38% 8.68% 8.31% 7.93% 7.39% 7.35% 1 Close Mortgage Loan Volume $ in millions Mortgage Closed Loan Volume Mortgage Pipeline Volume $31 $25 $27 $29 $32 $16 $17 $111 $110 $89 $78 $75 $69 $69 4Q23 1Q24 2Q24 3Q24 4Q24 1Q25 2Q25 1 Rate ready to close represents the weighted average rate on commercial loans that are ready to close and does not include fees, including FAS 91 fees, associated with those commercial loans 18

Loans: Conservative LTVs underpin prudent underwriting standards in key sectors Office (non-owner occupied permanent) Key Statistics At 6/30/25 Loan Portfolio – Geographic diversification By State By State NPL Ratio 0.00% 16% Past Due 30+ Days 0.00% 2% 19% 2% Average Loan Size $2.2M 33% 47% 8% Median Loan Size $0.5M $0.7B 2% Number of Loans <$1M 63% 4% 13% 1 Average LTV 47.3% $16.6B 12% 9% Weighted Average LTV 53.4% Texas Arkansas Tennessee Missouri Oklahoma Kansas Other Multifamily (permanent) Key Statistics At 6/30/25 19% 14% By State 6% NPL Ratio 1.29% 14% Texas Arkansas Tennessee Missouri 37% Past Due 30+ Days 0.24% Oklahoma Kansas Other 5% Average Loan Size $3.0M $0.9B 6% Median Loan Size $0.6M % of Total % of Total Top 10 MSAs Number of Loans <$1M 65% 1 1 Loans Commitments 15% 17% Average LTV 51.4% Dallas-Plano-Irving 9.5% 9.2% Texas Arkansas Tennessee Missouri Oklahoma Kansas Other Weighted Average LTV 62.3% Houston-Sugarland-Baytown 8.9% 8.3% Little Rock-North Little Rock-Conway 5.8% 6.0% Retail (non-owner occupied permanent) Key Statistics At 6/30/25 Nashville-Davidson-Murfreesboro 5.0% 5.9% By State NPL Ratio 0.47% 14% Memphis 5.0% 4.8% 1% Past Due 30+ Days 0.02% Fort Worth-Arlington 4.1% 4.0% 5% 47% Average Loan Size $1.8M Fayetteville-Springdale-Rogers 3.2% 3.1% 8% $0.9B Median Loan Size $0.9M St. Louis 2.7% 2.6% Number of Loans <$1M 51% 11% Kansas City 2.1% 2.4% Average LTV 48.1% Jonesboro 2.1% 2.1% 14% Weighted Average LTV 56.0% Texas Arkansas Tennessee Missouri Oklahoma Kansas Other Data shown above as of June 30, 2025 1 Total loans or commitments excluding credit card portfolio and mortgage warehouse 19

CLD: Quick recycling of capital given short duration of portfolio Construction and Land Development (CLD) By State % of Total % of Total Key Statistics At 6/30/25 Top 10 MSAs Loans Commitments NPL Ratio 0.36% Dallas-Plano-Irving 10.6% 10.3% Past Due 30+ Days 0.19% 29% Nashville-Davidson-Murfreesboro 8.2% 10.0% 43% Average Loan Size $1.4M Houston-Sugarland-Baytown 8.7% 7.7% Median Loan Size $0.3M Memphis 6.4% 5.4% $2.8B Number of Loans <$1M 84% 1% Little Rock-North Little Rock-Conway 5.7% 5.0% Average LTV 56.4% 2% Fort Worth-Arlington 4.4% 4.3% 4% Weighted Average LTV 53.7% Corpus Christi 2.7% 2.3% Weighted Average Maturity ~20 months 12% 9% Fayetteville-Springdale-Rogers 2.5% 2.5% Texas Arkansas Tennessee Missouri Orlando-Kissimmee-Sanford 2.3% 2.6% Oklahoma Kansas Other Phoenix-Mesa-Glendale 1.2% 3.8% CLD - Industrial Warehouse (non-owner occupied) CLD - Multifamily By State By State Key Statistics At 6/30/25 Key Statistics At 6/30/25 NPL Ratio 0.02% NPL Ratio 0.00% 19% Texas 24% Texas Past Due 30+ Days 0.00% Past Due 30+ Days 0.00% 42% Arkansas 40% Tennessee Average Loan Size $19.2M Average Loan Size $11.4M Tennessee Missouri $0.9B $0.5B 22% Median Loan Size $20.3M 5% Median Loan Size $5.5M Kansas Florida Number of Loans <$1M 30% 6% Number of Loans <$1M 35% Florida Other Average LTV 48.9% 7% Average LTV 41.1% Other 5% 14% 16% Weighted Average LTV 49.5% Weighted Average LTV 44.1% Weighted Average Maturity ~14 months Weighted Average Maturity ~13 months Data shown above as of June 30, 2025 20

Loans: Loan portfolio by type and key credit metrics as of March 31, 2025 as of June 30, 2025 % of % of Past Due 30+ Unfunded Unfunded Balance Total Balance Total Days Classified Nonperforming Commitment ACL Commitment $ in millions $ Loans $ Loans $ $ $ $ % Reserve Total Loan Portfolio Credit Card 180 1% 176 1% 2 1 1 - 3.46% - Consumer – Other 97 1% 124 1% 1 - - 34 2.73% 0.59% Real Estate – Construction 2,778 16% 2,785 16% 5 13 10 1,900 1.49% 1.03% Real Estate – Commercial 8,051 47% 7,961 47% 4 321 78 288 1.51% 0.34% Real Estate - Single-family 2,647 15% 2,626 15% 14 41 34 313 1.62% 0.80% Commercial 2,373 14% 2,440 14% 2 59 33 1,256 1.43% 0.16% Mortgage Warehouse 371 2% 324 2% - - - - 0.20% - Agriculture 265 2% 333 2% 1 2 1 155 0.66% 0.16% Other 332 2% 342 2% - - - 1 0.65% 0.06% Total Loan Portfolio 17,094 100% 17,111 100% 29 437 157 3,947 1.48% 0.65% Loan Concentration (Holding Company Level) C&D 93% 94% CRE 269% 268% Select Loan Categories Retail 1,227 7% 1,164 7% - 6 5 122 0.89% 0.61% Nursing / Extended Care 240 1% 231 1% - 108 - 2 7.71% 0.03% Healthcare 606 4% 586 3% - 19 3 93 1.10% 0.13% Multifamily 1,808 11% 1,852 11% 2 36 12 501 1.33% 0.51% Hotel 702 4% 698 4% - 61 27 164 3.98% 1.66% Restaurant 582 3% 603 4% - 37 28 33 3.64% 0.44% NOO Office 811 5% 782 5% - 15 8 127 2.43% 1.40% NOO Industrial Warehouse 1,366 8% 1,371 8% - 18 1 459 0.29% 0.14% 1 Run-Off Portfolio 57 <1% 47 <1% 1 4 4 12 7.16% - 1 “Run-off portfolio” consists of small ticket equipment finance and acquired asset based lending portfolios 21

Credit Quality 22

Credit Quality: Underlying credit metrics remain healthy Key Credit Quality Metrics 2Q24 3Q24 4Q24 1Q25 2Q25 Commentary Loans past due 30-89 days 0.15% 0.20% 0.22% 0.21% 0.17% ❑ Underlying credit metrics remain healthy Net charge-off ratio 0.19% 0.22% 0.27% 0.23% 0.25% ▪ 17 bps of loans past due 30-89 days, down 4 bps from 1Q25 levels 0.60% 0.59% 0.65% 0.89% 0.92% NPL ratio 1 ▪ 25 bps of net charge-offs in 2Q25; 3 bps associated with run-off portfolio 2 NPL ratio excluding Two Specific Credit Relationships 0.60% 0.63% 2 ▪ 63 bps NPL ratio excluding Two Specific Credit Relationships 0.39% 0.38% 0.45% 0.61% 0.62% NPA to total assets 2 NPA ratio excluding Two Specific Credit Relationships 0.42% 0.44% ❑ Two Specific Credit Relationships represent 57% of our Top 10 NPLs ACL to total loans 1.34% 1.35% 1.38% 1.48% 1.48% ▪ Continue to work closely with borrowers on resolution strategies Reserve for unfunded commitments 0.68% 0.70% 0.69% 0.66% 0.65% Top 10 Nonperforming Loans Nonperforming Loans Industry Outstanding ACL Reserve Reserve % $ in millions 1 CRE - Hotel $26.7M $16.8M 63% 57% $157.2 $152.4 of Top 10 2 CRE - Restaurant/C&I* $22.9M $13.9M 61% NPLs $49.6 $49.8 3 CLD – Office $8.5M $2.2M 26% $110.8 $103.4 $101.7 $5.5 $3.5 4 CRE – Multifamily* $6.8M - - $3.8 $7.4 $15.6 5 CRE - Ministorage $6.8M $1.0M 17% 6 CRE – Multifamily* $5.2M $1.1M 20% $105.3 $104.1 $98.8 $94.3 $87.8 7 C&I – Transportation $2.7M <$0.1M 2% 8 CRE – Owner Occupied $2.6M - - 2Q24 3Q24 4Q24 1Q25 2Q25 9 CRE – NOO Retail $2.5M - - Core Portfolio Run-Off Portfolio Two Specific Credit Relationships 10 C&I – Oil & Gas $2.4M $0.9M 38% 1 “Run-off portfolio” consists of small ticket equipment finance and acquired asset based lending portfolios 2 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations 23 * Represents acquired relationship from recent bank acquisitions. In the case of restaurant/C&I, the CRE portion of the relationship was from the most recent bank acquisition For purposes of the slides in this presentation, “Two Specific Credit Relationships” refers to the first two loans in the “Top 10 Nonperforming Loans” table on this slide

Credit Quality: Nonperforming and past due loans Nonperforming Loans Evolution $ in millions $1.7 $10.7 $0.4 $157.2 $152.4 $(0.2) $(4.2) $(0.2) $(3.4) Run-Off 1Q25 RE - RE - RE – Commercial Consumer & Two Specific 2Q25 1 Construction Commercial Single Family Other Portfolio Credit Relationships 2 2 2 Past Due 30-89 days / Total Loans Nonperforming Loans / Total Loans Nonperforming Assets / Total Assets Strategic decision to de-risk certain elements of the loan portfolio through the planned exit of particular acquired non- relationship credits Annual Quarterly Annual Quarterly Annual Quarterly 0.96% 0.92% 0.64% 0.89% 0.62% 0.61% 0.55% 0.65% 0.65% 0.45% 0.45% 0.60% 0.59% 0.57% 0.39% 0.38% 0.50% 0.33% 0.65% 0.31% 0.42% 0.60% 0.63% 0.44% 0.24% 0.22% 0.21% 0.24% 0.22% 0.21% 0.20% 0.17% 0.15% 0.37% 0.11% 0.23% 0.18% NPL Ratio NPL Ratio, excluding Two Specific Credit Relationships3 NPA to Assets NPA to Assets, excluding Two Specific Credit Relationships3 2019 2020 2021 2022 2023 2024 2Q24 3Q24 4Q24 1Q25 2Q25 2019 2020 2021 2022 2023 2024 2Q24 3Q24 4Q24 1Q25 2Q25 2019 2020 2021 2022 2023 2024 2Q24 3Q24 4Q24 1Q25 2Q25 Source: S&P Global Market Intelligence 2019 – 2024; Company Reports 1 Consumer & Other includes credit card, consumer-other, mortgage warehouse, agriculture and other loan portfolios 24 2 As of December 31, for each respective year shown above; quarterly data as of the end of the quarter for each respective period 3 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations

ACL: Loan loss provision and net charge-offs Loan Loss Provision and Net Charge-Off Ratio Commentary $ in millions $40.0 0.40% ❑ NCO ratio of 25 bps in 2Q25; provision expense exceeded net charge-offs 0.27% 0.25% 0.30% $35.0 0.22% 0.23% 1 0.19% ▪ 3 bps associated with run-off portfolio 0.20% $30.0 $26.8▪ 3 bps associated with credit card portfolio 0.10% $25.0 ❑ ACL to total loans ended 2Q25 at 1.48%, unchanged from 1Q25 0.00% $20.0 -0.10% $13.3 $15.0 $12.1 $11.9 $11.1 -0.20% $1.8 $1.4 ACL METHODOLOGY AS OF 6/30/25 $2.8 $2.2 $10.0 $3.0 -0.30% ▪ Moody’s June 2025 scenarios with management’s weighting: $11.5 $5.0 Baseline (75%) / S1 (15%) / S3 (10%) $10.6 $9.3 $9.6 -0.40% $8.1 ▪ Total credit coverage / total commitments: 1.33% $0.0 -0.50% 2Q24 3Q24 4Q24 1Q25 2Q25 ACL and ACL to Total Loans NCO Provision Incremental Provision Provision attributable to Two Specific Credit Relationships NCO Ratio $ in millions $275.0 1.75% 1.48% 1.48% 1.55% 1.38% 1.35% 1.34% $250.0 1.35% $253.5 $252.2 1.15% Reserve for Unfunded Commitments $235.0 $225.0 $233.2 $230.4 0.95% As of As of As of As of As of $ in millions 6/30/24 9/30/24 12/31/24 3/31/25 6/30/25 0.75% $200.0 Unfunded Commitments $3,746 $3,681 $3,739 $3,888 $3,947 0.55% Reserve for Unfunded Commitments $25.6 $25.6 $25.6 $25.6 $25.6 0.35% $175.0 0.15% Provision for Unfunded Commitments - - - - - $150.0 -0.05% Reserve / Unfunded Balance 0.68% 0.70% 0.69% 0.66% 0.65% 2Q24 3Q24 4Q24 1Q25 2Q25 ACL ACL to Total Loans 1 “Run-off portfolio” consists of small ticket equipment finance and acquired asset based lending portfolios 25

Forward-Looking Statements and Non-GAAP Financial Measures Forward-Looking Statements. Certain statements by Simmons First National Corporation (the “Company”, which where appropriate includes the Company’s wholly-owned banking subsidiary, Simmons Bank) contained in this presentation may not be based on historical facts and should be considered forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements may be identified by reference to a future period(s) or by the use of forward-looking terminology, such as anticipate, “believe,” “continue,” estimate, expect, foresee,“ “indicate,” “plan,” “potential,” “project,” “target,” may, might, will, would, could,“ “should,” “likely” or intend, future or conditional verb tenses, and variations or negatives of such terms or by similar expressions. These forward-looking statements include, without limitation, statements relating to the Company’s future growth; business strategies; product development; revenue; expenses (including interest expense and non-interest expenses); assets; loan demand (including loan growth, loan capacity, and other lending activity); deposit levels; dividends; asset quality; profitability; earnings; critical accounting policies; accretion; net interest margin; noninterest income; the Company's common stock repurchase program; adequacy of the allowance for credit losses; income tax deductions; credit quality; level of credit losses from lending commitments; net interest revenue; interest rate sensitivity (including, among other things, the potential impact of rising rates); loan loss experience; liquidity; capital resources; future economic conditions and market risk; interest rates; the Company’s securities portfolio, including cash flows and unrealized losses thereon; legal and regulatory limitations and compliance and competition; anticipated loan principal reductions; plans for investments in and cash flows from securities; the estimated annual impact of securities sales; projections regarding loan repricing, securities investments and maturities thereof; the estimates of future swap income set forth on slide 7; the interest rate sensitivity estimates and projections set forth on slide 14; and the AOCI burn down projections set forth on slide 12. Readers are cautioned not to place undue reliance on the forward-looking statements contained in this presentation in that actual results could differ materially from those indicated in or implied by such forward-looking statements due to a variety of factors. These factors include, but are not limited to, changes in the Company's operating or expansion strategy; the availability of and costs associated with obtaining adequate and timely sources of liquidity; changes in credit quality; changes in general market and economic conditions; increased unemployment; labor shortages; possible adverse rulings, judgments, fines, settlements and other outcomes of pending or future litigation; the ability of the Company to collect amounts due under loan agreements; significant increases in nonaccrual loan balances; changes in consumer preferences and loan demand; the effectiveness of the Company's interest rate risk management strategies; laws and regulations affecting financial institutions in general or relating to taxes; the effect of pending or future legislation; changes in governmental administrations; the ability of the Company to repurchase its common stock on favorable terms; the ability of the Company to successfully manage and implement its acquisition strategy and integrate acquired institutions; changes in tariff policies; difficulties and delays in integrating an acquired business or fully realizing cost savings and other benefits of mergers and acquisitions; changes in interest rates, deposit flows, real estate values, and capital markets; increased inflation; customer acceptance of the Company's products and services and changes in customer behaviors; changes or disruptions in technology and IT systems (including cyber or other information technology threats, attacks and events); changes in accounting principles relating to loan loss recognition (current expected credit losses, or CECL); fraud that results in material losses or that we have not discovered yet that may result in material losses; the benefits associated with the Company’s early retirement program; pandemics or significant health hazards, severe weather conditions, natural disasters, terrorist activities, political crises, war, and other military conflicts (including the ongoing military conflicts between Russia and Ukraine and between Israel and Iran) or other major events, or the prospect of these events; increased competition in the markets in which the Company operates and from non-bank financial institutions; changes in governmental policies; loss of key employees; reliance on third parties for key services; the soundness of other financial institutions and any indirect exposure related to the closings of other financial institutions and their impact on the broader market through other customers, suppliers and partners, or that the conditions which resulted in the liquidity concerns experienced by closed financial institutions may also adversely impact, directly or indirectly, other financial institutions and market participants with which the Company has commercial or deposit relationships; increased delinquency and foreclosure rates on commercial real estate and other loans; and other risk factors. Other relevant risk factors are detailed in the Company’s Form 10-K for the year ended December 31, 2024, and other reports that the Company has filed with or furnished to the U.S. Securities and Exchange Commission (the SEC), all of which are available from the SEC on its website, www.sec.gov. In addition, there can be no guarantee that the board of directors (“Board”) of the Company will approve a quarterly dividend in future quarters, and the timing, payment, and amount of future dividends (if any) is subject to, among other things, the discretion of the Board and may differ significantly from past dividends. Any forward-looking statement speaks only as of the date of this presentation, and the Company undertakes no obligation to update these forward-looking statements to reflect events or circumstances that occur after the date of this presentation. Annualized, pro forma, projected and estimated numbers are used for illustrative purpose only, are based on hypothetical assumptions that may not accurately reflect future incomes, are not forecasts and are not guaranteed and may differ significantly from actual results. Non-GAAP Financial Measures. This presentation contains financial information determined by methods other than in accordance with U.S. generally accepted accounting principles (“GAAP”). The Company’s management uses these non-GAAP financial measures in their analysis of the Company’s performance and capital adequacy. These measures adjust GAAP performance measures to, among other things, include the tax benefit associated with revenue items that are tax-exempt, as well as exclude from net income (including on a per share diluted basis), pre-tax, pre-provision earnings, net charge-offs, income available to common shareholders, non-interest income, and non-interest expense certain income and expense items attributable to, for example, merger activity (primarily including merger-related expenses), gains and/or losses on sale of branches, net branch right-sizing initiatives, early retirement program, termination of vendor and software services, FDIC special assessment charges and expenses related to the fraud event reported in the first quarter of 2025. In addition, the Company also presents certain figures based on tangible common stockholders’ equity, tangible assets and tangible book value, which exclude goodwill and other intangible assets, and presents certain other figures to include the effect that accumulated other comprehensive income could have on the Company’s capital levels. The Company further presents certain figures that are exclusive of the impact of deposits and/or loans acquired through acquisitions, mortgage warehouse loans, and/or energy loans, gains and/or losses on the sale of securities, or the Two Specific Credit Relationships. The Company’s management believes that these non-GAAP financial measures are useful to investors because they, among other things, present the results of the Company’s ongoing operations without the effect of mergers or other items not central to the Company’s ongoing business, present the Company’s capital inclusive of the potential impact of AOCI (primarily comprised of unrealized losses on securities), as well as normalize for tax effects and certain other effects. Management, therefore, believes presentations of these non-GAAP financial measures provide useful supplemental information that is essential to a proper understanding of the operating results of the Company’s ongoing businesses, and management uses these non-GAAP financial measures to assess the performance of the Company’s ongoing businesses as related to prior financial periods. These non-GAAP disclosures should not be viewed as a substitute for operating results determined in accordance with GAAP, nor are they necessarily comparable to non-GAAP performance measures that may be presented by other companies. Where non-GAAP financial measures are used, the comparable GAAP financial measure, as well as the reconciliation to the comparable GAAP financial measure, can be found in the appendix to this presentation. 26

Appendix 27

Select Balance Sheet and Other Data 2Q25 vs 1Q25 2Q25 vs 2Q24 $ in millions, except per share data 2Q25 1Q25 2Q24 $ Change % Change $ Change % Change Period End Balances Total loans $17,111.1 $17,094.1 $17,192.4 $17.0 - % ($81.3) - % Investment securities 5,996.9 6,107.4 6,571.4 ( 110.6) (2) (574.5) (9) Total assets 26 ,693.6 26 ,793.0 27 ,369.1 ( 99.4) - (675.5) (2) Total deposits 21 ,825.0 21 ,684.6 21 ,840.9 14 0.4 1 (15.9) - Borrowed funds 1,032.0 1,301.3 1,765.3 (269.3) (21) (733.3) (42) Total stockholders' equity 3,549.2 3,531.5 3,458.9 17.7 1 90.3 3 Average Balances Total loans $17,046.8 $16,920.1 $17,101.8 $126.8 1 % ($55.0) - % Investment securities 6,047.8 6,148.6 6,632.5 (100.8) (2) (584.7) (9) Total assets 26 ,645.1 26 ,678.6 27,305.3 ( 33.5) - (660.1) (2) Total deposits 21 ,431.0 21,680.9 22 ,045.5 ( 249.9) (1) ( 614.5) (3) Borrowed funds 1,359.7 1,112.5 1,528.5 24 7.2 22 (168.8) (11) Total stockholders' equity 3,546.2 3,564.5 3,451.2 (18.3) (1) 95 .0 3 Select Other Data Equity to assets 13.30 % 13.18 % 12.64 % 1 Tangible common equity to tangible assets 8.46 8.34 7.84 Book value per share $28.17 $28.04 $27.56 $0.13 - % $0.61 2 % 1 16.97 16.81 16.20 0. 16 1 0. 77 5 Tangible book value per share Allowance for credit losses to total loans 1.48 % 1.48 % 1.34 % Nonperforming loan coverage ratio 161 165 223 1 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations 28

Income Summary 2Q25 Adjusted 2Q25 vs Adjusted 1 $ in millions, except per share data 1Q25 2Q24 Reported Adjusted Net interest income $171.8 $171.8 $8.4 5 % $ 17.9 12 % Noninterest income 4 2.4 4 2.4 (3.8) (8) (0.9) (2) Total revenue 214.2 214.2 4.6 2 17.0 9 Noninterest expense 138.6 136.8 (6.8) (5) (1.0) (1) 2 7 5.6 7 7.3 11.4 17 18.0 30 Pre-provision net revenue Provision for credit losses 1 1.9 11.9 (14.9) (55) 0.8 8 Provision for income taxes 8.9 9.3 3.3 54 2.9 46 Earnings $ 54.8 $ 56.1 $22.9 69 % $14.2 34 % Diluted EPS $ 0.43 $ 0.44 $0.18 69 % $0.11 33 % Totals may not foot due to rounding 1 Non-GAAP measures that management believes aid in the discussion of results. See appendix for Non-GAAP reconciliations 29 2 All pre-provision net revenue (PPNR) figures set forth in this row are Non-GAAP measures. See footnote 1 for more information

Non-GAAP Reconciliations 2Q 3Q 4Q 1Q 2Q $ in thousands, except per share data 2024 2024 2024 2025 2025 1 Calculation of Adjusted Earnings Net Income $ 40,763 $ 24,740 $ 48,319 $ 32,388 $ 54,773 Certain items Branch right sizing, net 519 410 1,581 994 163 Loss (gain) on sale of securities - 28,393 - - - Early retirement program 118 (1) 200 - 1,594 FDIC special assessment 283 - - - - Termination of vendor and software services 615 (13) - - - 2 Tax effect (401) (7,524) (466) (260) (459) Certain items, net of tax 1,134 21,265 1,315 734 1,298 Adjusted earnings (non-GAAP) $ 41,897 $ 46,005 $ 49,634 $ 33,122 $ 56,071 1 Calculation of Earnings and Adjusted Earnings per Diluted Share Earnings available to common shareholders $ 40,763 $ 24,740 $ 48,319 $ 32,388 $ 54,773 Diluted earnings per share $ 0.32 $ 0.20 $ 0.38 $ 0.26 $ 0.43 Adjusted earnings available to common shareholders (non-GAAP) $ 41,897 $ 46,005 $ 49,634 $ 33,122 $ 56,071 Adjusted diluted earnings per share (non-GAAP) $ 0.33 $ 0.37 $ 0.39 $ 0.26 $ 0.44 Average Diluted Shares Outstanding 125,758,166 125,999,269 126,232,084 126,336,557 126,406,879 1 In this presentation, “Adjusted Earnings” may also be referred to as “Adjusted Net Income” 2 Effective tax rate of 26.135% 30

Non-GAAP Reconciliations 2Q 3Q 4Q 1Q 2Q 2024 2024 2024 2025 2025 $ in thousands Calculation of Pre-Provision Net Revenue (PPNR) Net interest income $ 153,905 $ 157,712 $ 164,942 $ 163,422 $ 171,824 Noninterest income 43,299 17,130 43,558 46,155 42,354 Less: Noninterest expense 139,354 137,193 141,117 144,580 138,589 Pre-Provision Net Revenue (PPNR) (non-GAAP) $ 57,850 $ 37,649 $ 67,383 $ 64,997 $ 75,589 Calculation of Adjusted Pre-Provision Net Revenue Pre-Provision Net Revenue (PPNR) (non-GAAP) $ 57,850 $ 37,649 $ 67,383 $ 64,997 $ 75,589 Plus: (Gain) loss on sale of securities - 28,393 - - - Plus: Branch right sizing costs, net 519 410 1,581 994 163 Plus: FDIC special assessment 283 - - - - Plus: Early retirement program 118 (1) 200 - 1,594 Plus: Termination of vendor and software services 615 (13) - - - Adjusted Pre-Provision Net Revenue (non-GAAP) $ 59,385 $ 66,438 $ 69,164 $ 65,991 $ 77,346 Calculation of Book Value and Tangible Book Value per Share Total common stockholders' equity $ 3,458,869 $ 3,528,833 $ 3,528,872 $ 3,531,485 $ 3,549,210 Intangible assets: Goodwill (1,320,799) (1,320,799) (1,320,799) (1,320,799) (1,320,799) Other intangible assets (104,943) (101,093) (97,242) (93,714) (90,617) Total intangible assets (1,425,742) (1,421,892) (1,418,041) (1,414,513) (1,411,416) Tangible common stockholders' equity (non-GAAP) $ 2,033,127 $ 2,106,941 $ 2,110,831 $ 2,116,972 $ 2,137,794 Shares of common stock outstanding 125,487,520 125,554,598 125,651,540 125,926,822 125,996,248 Book value per common share $ 27.56 $ 28.11 $ 28.08 $ 28.04 $ 28.17 Tangible book value per common share (non-GAAP) $ 16.20 $ 16.78 $ 16.80 $ 16.81 $ 16.97 31

Non-GAAP Reconciliations 2Q 3Q 4Q 1Q 2Q 2024 2024 2024 2025 2025 $ in thousands, except number of employees (FTE) Calculation of Total Revenue and Adjusted Total Revenue Net Interest Income (GAAP) $ 153,905 $ 157,712 $ 164,942 $ 163,422 $ 171,824 Noninterest Income (GAAP) 43,299 17,130 43,558 46,155 42,354 Total Revenue (non-GAAP) $ 197,204 $ 174,842 $ 208,500 $ 209,577 $ 214,178 Total Revenue (non-GAAP) $ 197,204 $ 174,842 $ 208,500 $ 209,577 $ 214,178 Less: Gain (loss) on sales of securities - (28,393) - - - Adjusted Total Revenue (non-GAAP) $ 197,204 $ 203,235 $ 208,500 $ 209,577 $ 214,178 Employees (FTE) 2,961 2,972 2,946 2,949 2,947 Total Revenue per Employee (FTE) $ 66.60 $ 58.83 $ 70.77 $ 71.07 $ 72.68 Adjusted Total Revenue per Employee (FTE) $ 66.60 $ 68.38 $ 70.77 $ 71.07 $ 72.68 Calculation of Adjusted Noninterest Income Noninterest Income (GAAP) $ 43,299 $ 17,130 $ 43,558 $ 46,155 $ 42,354 Less: Gain (loss) on sale of securities - (28,393) - - - Adjusted Noninterest Income (non-GAAP) $ 43,299 $ 45,523 $ 43,558 $ 46,155 $ 42,354 Calculation of Noninterest Income to Total Revenue Noninterest Income to Total Revenue 21.96% 9.80% 20.89% 22.02% 19.78% Adjusted Noninterest Income to Adjusted Total Revenue (non-GAAP) 21.96% 22.40% 20.89% 22.02% 19.78% Calculation of Total Revenue and Adjusted Total Revenue Per Share Average Diluted Shares Outstanding 125,758,166 125,999,269 126,232,084 126,336,557 126,406,879 Total Revenue per Average Diluted Shares Outstanding $ 1.57 $ 1.39 $ 1.65 $ 1.66 $ 1.69 Adjusted Total Revenue per Average Diluted Shares Outstanding (non-GAAP) $ 1.57 $ 1.61 $ 1.65 $ 1.66 $ 1.69 FTE – Full time equivalent 32

Non-GAAP Reconciliations 2Q 3Q 4Q 1Q 2Q 2024 2024 2024 2025 2025 $ in thousands Calculation of Adjusted Noninterest Expense Noninterest Expense (GAAP) $ 139,354 $ 137,193 $ 141,117 $ 144,580 $ 138,589 Less: Branch right sizing expense 519 410 1,581 994 163 Less: Early retirement program 118 (1) 200 - 1,594 Less: FDIC special assessment 283 - - - - Less: Termination of vendor and software services 615 (13) - - - Adjusted Noninterest Expense (non-GAAP) $ 137,819 $ 136,797 $ 139,336 $ 143,586 $ 136,832 Calculation of Noninterest Expense to Average Assets Average total assets $ 27,305,277 $ 27,216,440 $ 27,078,943 $ 26,678,628 $ 26,645,131 Noninterest expense to average total assets 2.05% 2.01% 2.07% 2.20% 2.09% Adjusted noninterest expense to average assets (non-GAAP) 2.03% 2.00% 2.05% 2.18% 2.06% Calculation of Efficiency Ratio and Adjusted Efficiency Ratio Noninterest Expense (efficiency ratio numerator) $ 139,354 $ 137,193 $ 141,117 $ 144,580 $ 138,589 Total Revenue $ 197,204 $ 174,842 $ 208,500 $ 209,577 $ 214,178 Fully taxable equivalent adjustment ___ _ _6,576 ___ _ _6,398 ___ _ _6,424 ___ _ _6,414 ___ _ _6,422 Efficiency ratio denominator $ 203,780 $ 181,240 $ 214,924 $ 215,991 $ 220,600 Efficiency ratio (based on GAAP figures) 68.38% 75.70% 65.66% 66.94% 62.82% Adjusted Noninterest Expense (non-GAAP) $ 137,819 $ 136,797 $ 139,336 $ 143,586 $ 136,832 Less: Other real estate and foreclosure expense 117 87 317 198 216 Less: Amortization of intangible assets ___ __ 3,852 ___ __ 3,851 ___ __ 3,850 ___ __ 3,527 ___ __ 3,098 Adjusted efficiency ratio numerator (non-GAAP) $ 133,850 $ 132,859 $ 135,169 $ 139,861 $ 133,518 Adjusted Total Revenue (non-GAAP) (reconciliation shown on page 32) $ 197,204 $ 203,235 $ 208,500 $ 209,577 $ 214,178 Fully taxable equivalent adjustment ___ _ _6,576 ___ _ _6,398 ___ _ _6,424 ___ _ _6,414 ___ _ _6,422 Adjusted efficiency ratio denominator (non-GAAP) $ 203,780 $ 209,633 $ 214,924 $ 215,991 $ 220,600 Adjusted Efficiency Ratio (non-GAAP) 65.68% 63.38% 62.89% 64.75% 60.52% Fully taxable equivalent adjustment using an effective tax rate of 26.135% 33

Non-GAAP Reconciliations 2Q 1Q 2Q 2024 2025 2025 $ in thousands Calculation of Adjusted Salaries and Employee Benefits Salaries and employee benefits (GAAP) $ 70,716 $ 74,824 $ 73,862 Less: Early retirement program 118 - 1,594 Less: Other (1) - (1) Total Adjusted Salaries and Employee Benefits (non-GAAP) $ 70,599 $ 74,824 $ 72,269 Calculation of Adjusted Occupancy Expense, Net Occupancy expense, net (GAAP) $ 11,864 $ 12,651 $ 11,844 Less: Branch right sizing expense 125 744 396 Total Adjusted Occupancy Expense (non-GAAP) $ 11,739 $ 11,907 $ 11,448 Calculation of Adjusted Furniture and Equipment Expense Furniture and Equipment Expense (GAAP) $ 5,623 $ 5,465 $ 5,474 Less: Branch right sizing expense 3 89 23 Total Adjusted Furniture and Equipment Expense (non-GAAP) $ 5,620 $ 5,376 $ 5,451 Calculation of Adjusted Other Noninterest Expense Other noninterest expense (GAAP) $ 45,352 $ 46,051 $ 42,276 Less: Branch right sizing expense 1,007 161 (255) Total Adjusted Other Noninterest Expense (non-GAAP) $ 44,345 $ 45,890 $ 42,531 Calculation of Adjusted Provision for Income Taxes Provision for income taxes (GAAP) $ 5,988 $ 5,812 $ 8,871 Less: Tax effect of certain items (non-GAAP) (reconciliation shown on page 30) (401) (260) (459) Adjusted provision for income taxes (non-GAAP) $ 6,389 $ 6,072 $ 9,330 34

Non-GAAP Reconciliations 2Q 1Q 2Q 2024 2025 2025 $ in thousands Calculation of Tangible Common Equity (TCE) Total common stockholders’ equity $ 3,458,869 $ 3,531,485 $ 3,549,210 Less: Intangible assets (1,425,742) (1,414,513) (1,411,416) Total tangible common stockholders’ equity (non-GAAP) $ 2,033,127 $ 2,116,972 $ 2,137,794 Total assets $ 27,369,072 $ 26,792,991 $ 26,693,620 Less: Intangible assets (1,425,742) (1,414,513) (1,411,416) Total tangible assets $ 25,943,330 $ 25,378,478 $ 25,282,204 Common equity to total assets 12.64% 13.18% 13.30% Tangible common equity to tangible common assets (non-GAAP) 7.84% 8.34% 8.46% Calculation of CET 1 Capital Ratio, Including the Impact of AOCI Total stockholders’ equity $ 3,458,869 $ 3,531,485 $ 3,549,210 CECL transition provision 30,873 - - Disallowed intangible assets, net of deferred tax (1,391,969) (1,381,953) (1,379,104) Unrealized loss (gain) on available for sale securities (AOCI) ____ _ 405,481 ____ _ 367,710 ____ _ 380,900 Total tier 1 capital (CET 1) $ 2,503,254 $ 2,517,242 $ 2,551,006 Total tier 1 capital (CET 1) $ 2,503,254 $ 2,517,242 $ 2,551,006 Less: Unrealized loss (gain) on available for sale securities (AOCI) 405,481 367,710 380,900 Total tier 1 capital, including AOCI (non-GAAP) $ 2,097,773 $ 2,149,532 $ 2,170,106 Risk weighted assets $ 20,856.194 $ 20,621,540 $ 20,646,324 CET 1 capital ratio 12.00% 12.21% 12.36% CET 1 capital ratio, including AOCI (non-GAAP) 10.06% 10.42% 10.51% 35

Non-GAAP Reconciliations 2Q 1Q 2Q 2024 2025 2025 $ in thousands Calculation of Uninsured, Non-Collateralized Deposit Coverage Ratio Uninsured deposits at Simmons Bank $ 8,186,903 $ 8,614,833 $ 8,407,847 Less: Collateralized deposits (excluding portion that is FDIC insured) 2,835,424 3,005,328 2,691,215 Less: Intercompany eliminations ______ 943,979 __ __1,073,500 _____1,121,932 Total uninsured, non-collateralized deposits (non-GAAP) $ 4,407,500 $ 4,536,005 $ 4,594,700 FHLB borrowing availability $ 4,910,000 $ 4,432,000 $ 5,133,000 Unpledged securities 4,145,000 4,197,000 3,697,000 1 Fed funds lines, Fed discount window and Bank Term Funding Program 2,065,000 1,780,000 1,894,000 Additional liquidity sources $ 11,120,000 $ 10,409,000 $ 10,724,000 Uninsured, non-collateralized deposit coverage ratio (non-GAAP) 2.5x 2.3x 2.3x Calculation of Net Charge-Off Ratio, Excluding Run-Off Portfolio Net charge-offs $ 8,077 $ 9,648 $ 10,576 Less: Net charge-offs from run-off portfolio ______ 6,700 ______ 1,900 ______ 1,100 Net charge-offs excluding run-off portfolio (non-GAAP) $ 1,377 $ 7,748 $ 9,476 Average total loans $ 17,101,799 $ 16,920,050 $ 17,046,802 Net charge-offs as a percentage of average total loans (annualized) (NCO ratio) 0.19% 0.23% 0.25% NCO ratio excluding NCOs associated with run-off portfolios (annualized) (non- GAAP) 0.03% 0.19% 0.22% 1 The Bank Term Funding Program closed for new loans on March 11, 2024. At no time did Simmons borrow funds under this program. 36

Non-GAAP Reconciliations 1Q 2Q 2025 2025 $ in thousands Calculation of NPL ratio, excluding Two Specific Credit Relationships Nonperforming loans $ 152,391 $ 157,162 Less: Two Specific Credit Relationships 49,761 49,572 Nonperforming Loans, excluding Two Specific Credit Relationships (non-GAAP) $ 102,630 $ 107,590 Total loans $ 17,094,078 $ 17,111,096 Less: Two Specific Credit Relationships 49,761 49,572 Total Loans, excluding Two Specific Credit Relationships (non-GAAP) $ 17,044,317 $ 17,061,524 Nonperforming loans ratio (NPL Ratio) 0.89% 0.92% NPL ratio, excluding Two Specific Credit Relationships (non-GAAP) 0.60% 0.63% Calculation of NPA to Total Assets, excluding Two Specific Credit Relationships Nonperforming assets $ 162,345 $ 166,715 Less: Two Specific Credit Relationships 49,761 49,572 Nonperforming Assets, excluding Two Specific Credit Relationships (non-GAAP) $ 112,584 $ 117,143 Total assets $ 26,792,991 $ 26,693,620 Less: Two Specific Credit Relationships 49,761 49,572 Total Assets, excluding Two Specific Credit Relationships (non-GAAP) $ 26,743,230 $ 26,644,048 Nonperforming assets to total assets 0.61% 0.62% Nonperforming assets to total assets, excluding Two Specific Credit Relationships (non-GAAP) 0.42% 0.44% 37

Nasdaq SFNC nd 2 Quarter 2025 Earnings Presentation July 17, 2025