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CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Income Statement [Abstract]      
Product and service revenue $ 23,223,265 $ 15,738,841 $ 4,832,773
Research and development contract revenue 3,886,114 3,597,870 7,459,783
Licensed technology revenue 516,563 135,938  
Total revenue 27,625,942 19,472,649 12,292,556
Cost of product and service revenue 30,669,602 23,111,151 7,246,453
Cost of research and development contract revenue 6,232,210 6,370,797 12,433,361
Research and development expense 5,655,748 12,901,170 16,324,373
Selling, general and administrative expenses 14,545,965 25,572,364 15,426,806
Gain on sale of assets (673,358) (3,217,594)  
Amortization of intangible assets 2,322,876 2,263,627 2,132,333
Operating loss (31,127,101) (47,528,866) (41,270,770)
Interest and other income and net realized losses from available-for-sale securities 248,430 1,056,932 1,689,299
Change in fair value of common stock warrant liability 3,447,153    
Change in fair value of auction rate securities repurchase agreement   (5,977,822) (4,246,524)
Net trading gain   5,977,822 4,246,524
Interest and other expense and foreign currency gain (loss) (22,436) (486,987) (1,127,081)
Net loss $ (27,453,954) $ (46,958,921) $ (40,708,552)
Loss per share:      
Basic and diluted (in dollars per share) $ (1.46) $ (3.58) $ (3.15)
Weighted average number of common shares outstanding (In shares) 18,778,066 13,123,162 12,911,066