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Consolidated Statements of Changes in Equity - 9 months ended Sep. 30, 2018 - USD ($)
$ in Thousands
Total
Common Stock
Deficit
Accumulated other comprehensive income
Total shareholders' equity
Non-controlling interests
Beginning balance ( in shares) at Dec. 31, 2017   74,366,824        
Beginning balance at Dec. 31, 2017 $ 129,742 $ 430,383 $ (306,813) $ 2,289 $ 125,859 $ 3,883
Increase (Decrease) in Stockholders' Equity [Roll Forward]            
Net loss (17,582)   (17,485)   (17,485) (97)
Other comprehensive loss 657     657 657  
Shares issued for cash by at-the-market offering (in shares)   12,573,674        
Shares issued for cash by at-the-market offering 26,295 $ 26,295     26,295  
Shares issued for acquisition of Royalties (in shares)   1,102,840        
Shares issued for acquisition of Royalties 3,739 $ 3,739     3,739  
Share issuance cost (774) (774)     (774)  
Share-based compensation 2,241 $ 2,241     2,241  
Shares issued for exercise of stock options (in shares)   290,210        
Shares issued for exercise of stock options 619 $ 619     619  
Shares issued for exercise of warrants (in shares)   111,270        
Shares issued for exercise of warrants 366 $ 366     366  
Shares issued for the vesting of restricted stock units (in shares)   899,192        
Shares issued for consulting services (in shares)   185,614        
Shares issued for consulting services 364 $ 364     364  
Shares issued for consulting services (in shares)   0        
Shares issued for consulting services (914) $ (914)     (914)  
Ending balance (in shares) at Sep. 30, 2018   89,529,624        
Ending balance at Sep. 30, 2018 $ 144,753 $ 462,319 $ (324,298) $ 2,946 $ 140,967 $ 3,786