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Stockholders' Equity (Tables) | 12 Months Ended
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Dec. 31, 2016
Stockholders' Equity |
Schedule of fair value weighted-average assumptions |
|  | Years Ended December 31, |
|  | 2016 |  | 2015 |  | 2014 |
Expected stock price volatility |  |  | 81.3 | % |  | 75.9 | % |  | 81.3 | %
Risk free interest rate |  |  | 1.5 | % |  | 1.7 | % |  | 1.9 | %
Expected life of options (years) |  |  | 6.25 |  |  | 6.25 |  |  | 6.25 |
Expected annual dividend per share |  | $ | 0.00 |  | $ | 0.00 |  | $ | 0.00 |
Summary of stock options outstanding |
|  | Number of Shares |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life |  | Aggregate Intrinsic Value |
|  | (in thousands) |  |  |  |  |  | (in millions) |
Options outstanding, December 31, 2013 |  |  | 9,041.1 |  | $ | 5.65 |  |  |  |  |  |  |
Granted |  |  | 2,993.1 |  | $ | 2.99 |  |  |  |  |  |  |
Exercised |  |  | (965.6 | ) | $ | 3.80 |  |  |  |  |  |  |
Forfeited |  |  | (1,047.9 | ) | $ | 5.76 |  |  |  |  |  |  |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Options outstanding, December 31, 2014 |  |  | 10,020.7 |  | $ | 5.02 |  |  |  |  |  |  |
Granted |  |  | 3,917.2 |  | $ | 11.61 |  |  |  |  |  |  |
Exercised |  |  | (2,070.3 | ) | $ | 5.43 |  |  |  |  |  |  |
Forfeited |  |  | (138.4 | ) | $ | 7.76 |  |  |  |  |  |  |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Options outstanding, December 31, 2015 |  |  | 11,729.2 |  | $ | 7.11 |  |  |  |  |  |  |
Granted |  |  | 5,114.1 |  | $ | 7.67 |  |  |  |  |  |  |
Exercised |  |  | (723.1 | ) | $ | 4.20 |  |  |  |  |  |  |
Forfeited |  |  | (622.7 | ) | $ | 8.62 |  |  |  |  |  |  |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Options outstanding, December 31, 2016 |  |  | 15,497.5 |  | $ | 7.37 |  |  | 7.3 years |  | $ | 7.8 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Vested and unvested expected to vest, December 31, 2016 |  |  | (14,593.7 | ) | $ | 7.31 |  |  | 7.2 years |  | $ | 7.7 |
Exercisable at December 31, 2016 |  |  | 7,545.3 |  | $ | 6.57 |  |  | 5.8 years |  | $ | 5.8 |
Summary of non-vested Restricted Stock Units activity |
|  | Number of Share |  | Weighted Average Grant Date Fair Value |  | Weighted Average Remaining Years |  | Aggregate Intrinsic Value |
|  | (in thousands) |  |  |  |  |  | (in millions) |
Non-vested units as of December 31, 2014 |  |  | 955.0 |  | $ | 2.28 |  |  |  |  |  |  |
Granted |  |  | 366.0 |  | $ | 12.63 |  |  |  |  |  |  |
Vested |  |  | (842.5 | ) | $ | — |  |  |  |  |  |  |
Forfeited |  |  | — |  | $ | — |  |  |  |  |  |  |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Non-vested units as of December 31, 2015 |  |  | 478.5 |  | $ | 10.38 |  |  |  |  |  |  |
Granted |  |  | 582.7 |  | $ | 6.21 |  |  |  |  |  |  |
Vested |  |  | (281.9 | ) | $ | 8.73 |  |  |  |  |  |  |
Forfeited |  |  | (34.9 | ) | $ | 7.71 |  |  |  |  |  |  |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Non-vested units as of December 31, 2016 |  |  | 744.4 |  | $ | 7.86 |  |  | 2.62 |  | $ | — |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
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Summary of the equity-based compensation expense recognized in the statements of operations | The following table summarizes the equity-based compensation expense recognized in the statements of operations (in thousands):
|  | Years Ended December 31, |
|  | 2016 |  | 2015 |  | 2014 |
Equity compensation expense recognized in: |  |  |  |  |  |  |  |  |  |
Research and development expense |  | $ | 8,071 |  | $ | 4,600 |  | $ | 2,703 |
Selling, general and administrative expense |  |  | 9,433 |  |  | 5,372 |  |  | 3,305 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total equity compensation expense |  | $ | 17,504 |  | $ | 9,972 |  | $ | 6,008 |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
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