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Consolidated Statements of Operations - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2017 | Mar. 31, 2016
Revenue: |  |
Net product sales | $ 4,169 |
Cost of goods sold | 775 |
Gross Profit | 3,394 |
Operating Expenses: |  |
Research and development | 30,876 | $ 23,425
Selling, general and administrative | 19,132 | 15,701
Changes in fair value of contingent consideration payable | 4,578 | 3,152
Restructuring charges |  | 50
Depreciation | 823 | 673
Total operating expenses | 55,409 | 43,001
Loss from operations | (52,015) | (43,001)
Other income (expenses): |  |
Interest income | 759 | 307
Interest expense | (4,290) | (945)
Other income (expense) | 610 | (52)
Loss before income tax benefit | (54,936) | (43,691)
Income tax expense | (56) |
Net loss attributable to common stockholders | $ (54,992) | $ (43,691)
Net loss attributable to common stockholders per common share - basic and diluted | $ (0.39) | $ (0.35)
Weighted-average common shares outstanding - basic and diluted | 142,770,629 | 125,178,517

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