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Stockholders' Equity (Tables) | 3 Months Ended
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Mar. 31, 2017
Stockholders' Equity |
Schedule of fair value weighted-average assumptions |
|  | Three Months Ended March 31, |
|  | 2017 |  | 2016 |
Expected stock price volatility |  | 83.2 | % | 81.2 | %
Risk free interest rate |  | 2.1 | % | 1.8 | %
Expected life of options (years) |  | 6.25 |  | 6.25 |
Expected annual dividend per share |  | $ | 0.00 |  | $ | 0.00 |
Summary of stock options outstanding |
|  | Number of Shares |  | Weighted Average Exercise Price |  | Weighted Average Remaining Contractual Life |  | Aggregate Intrinsic Value |
|  | (in thousands) |  |  |  |  |  | (in millions) |
Options outstanding, December 31, 2016 |  | 15,497.5 |  | $ | 7.37 |  |  |  |  |
Granted |  | 2,605.3 |  | $ | 5.19 |  |  |  |  |
Exercised |  | (88.4 | ) | $ | 3.00 |  |  |  |  |
Forfeited |  | (192.6 | ) | $ | 9.24 |  |  |  |  |
Options outstanding, March 31, 2017 |  | 17,821.8 |  | $ | 7.05 |  | 7.5 years |  | $ | 26.1 |
Vested and unvested expected to vest, March 31, 2017 |  | 16,637.6 |  | $ | 7.05 |  | 7.3 years |  | $ | 24.8 |
Exercisable at March 31, 2017 |  | 8,564.0 |  | $ | 6.80 |  | 5.9 years |  | $ | 15.7 |
Summary of non-vested Restricted Stock Units activity |
|  | Number of Share (in thousands) |  | Weighted Average Grant Date Fair Value |  | Weighted Average Remaining Years |  | Aggregate Intrinsic Value (in millions) |
Non-vested units as of December 31, 2016 |  | 744.4 |  | $ | 7.86 |  |  |  |  |
Granted |  | 2,308.1 |  | $ | 5.64 |  |  |  |  |
Vested |  | (4.7 | ) | $ | 14.08 |  |  |  |  |
Forfeited |  | (25.9 | ) | $ | 5.81 |  |  |  |  |
Non-vested units as of March 31, 2017 |  | 3,021.9 |  | $ | 6.17 |  | 3 |  | $ | 21.5 |
Summary of the equity-based compensation expense recognized in the statements of operations | The following table summarizes information related to compensation expense recognized in the statements of operations related to the equity awards (in thousands):
|  | Three Months Ended March 31, |
|  | 2017 |  | 2016 |
Equity compensation expense recognized in: |  |  |  |  |
Research and development expense |  | $ | 2,753 |  | $ | 1,936 |
Selling, general and administrative expense |  | 3,277 |  | 2,347 |
Total equity compensation expense |  | $ | 6,030 |  | $ | 4,283 |

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- Definition Tabular disclosure of the number and weighted-average exercise prices (or conversion ratios) for share options (or share units) that were outstanding at the beginning and end of the year, vested and expected to vest, exercisable or convertible at the end of the year, and the number of share options or share units that were granted, exercised or converted, forfeited, and expired during the year. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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