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Description of Business (Details) $ / shares in Units, $ in Thousands	3 Months Ended
	Mar. 31, 2017 USD ($) $ / shares	Dec. 31, 2016 USD ($) $ / shares	May 31, 2016 item	Apr. 01, 2016
Corporate Information, Status of Operations and Management Plans
Number of Fabry causing mutations included in the label approved by the CHMP | item			313
Net product sales	$ 4,169
Common stock, par value (in dollars per share) | $ / shares	$ 0.01	$ 0.01
Accumulated deficit	$ (834,600)	$ (779,608)
Maximum
Corporate Information, Status of Operations and Management Plans
Percentage of patients with Fabry disease caused by mutations included in the label approved by the CHMP				0.5
Galafold | EU
Corporate Information, Status of Operations and Management Plans
Net product sales	$ 4,200

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Number of mutations causing Fabry disease included in approved CHMP label.

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Represents the portion of patients with Fabry disease caused by mutations included in the label approved by the CHMP.

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Face amount or stated value per share of common stock.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.29)
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Aggregate revenue during the period from the sale of goods in the normal course of business, after deducting returns, allowances and discounts.

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