XML 16 R6.htm IDEA: XBRL DOCUMENT v3.7.0.1
Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Operating activities    
Net loss $ (54,992) $ (43,691)
Adjustments to reconcile net loss to net cash used in operating activities:    
Non-cash interest expense 2,403 451
Depreciation 823 673
Stock-based compensation 6,030 4,283
Restructuring charges   50
Change in fair value of derivative liability (163)  
Non-cash changes in the fair value of contingent consideration payable 4,578 3,152
Foreign currency remeasurement loss (604)  
Non-cash deferred taxes 49  
Changes in operating assets and liabilities:    
Accounts receivable (512)  
Inventories (243)  
Prepaid expenses and other current assets (5,846) (94)
Other non-current assets (459) (377)
Accounts payable and accrued expenses (1,271) (9,763)
Non-current liabilities 363 380
Net cash used in operating activities (49,844) (44,936)
Investing activities    
Sale and redemption of marketable securities 69,443 53,157
Purchases of marketable securities (161,123) (50,721)
Purchases of property and equipment (732) (2,878)
Net cash used in investing activities (92,412) (442)
Financing activities    
Payment of capital leases (71)  
Purchase of vested restricted stock units (261) (657)
Proceeds from exercise of stock options 265 155
Payment of deferred financing fees (28)  
Net cash used in financing activities (95) (502)
Effect of exchange rate changes on cash and cash equivalents 80 (95)
Net decrease in cash and cash equivalents (142,271) (45,975)
Cash and cash equivalents at beginning of year/period 187,026 69,485
Cash and cash equivalents at end of year/period 44,755 $ 23,510
Supplemental disclosures of cash flow information    
Cash paid during the period for interest $ 12