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Consolidated Statements of Operations - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Revenue:        
Net product sales $ 10,874 $ 2,127 $ 22,201 $ 2,127
Cost of goods sold 1,790 344 3,626 344
Gross Profit 9,084 1,783 18,575 1,783
Operating Expenses:        
Research and development 40,641 32,457 103,502 74,163
Selling, general and administrative 21,647 17,469 60,090 52,470
Changes in fair value of contingent consideration payable (244,250) (4,110) (238,622) 9,228
Loss on impairment of assets 465,427   465,427  
Restructuring charges   11   69
Depreciation 851 896 2,486 2,336
Total operating expenses 284,316 46,723 392,883 138,266
Loss from operations (275,232) (44,940) (374,308) (136,483)
Other income (expenses):        
Interest income 1,190 460 2,702 1,098
Interest expense (4,351) (1,517) (12,820) (3,517)
Other income (expense) 2,044 (910) 5,054 (3,199)
Loss before income tax benefit (276,349) (46,907) (379,372) (142,101)
Income tax benefit 164,683 253 164,578 706
Net loss attributable to common stockholders $ (111,666) $ (46,654) $ (214,794) $ (141,395)
Net loss attributable to common stockholders per common share - basic and diluted $ (0.69) $ (0.33) $ (1.44) $ (1.07)
Weighted-average common shares outstanding - basic and diluted 160,796,841 140,656,109 148,963,864 131,675,690