<SEC-DOCUMENT>0000919574-17-001898.txt : 20170214
<SEC-HEADER>0000919574-17-001898.hdr.sgml : 20170214
<ACCEPTANCE-DATETIME>20170214130424
ACCESSION NUMBER:		0000919574-17-001898
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20170214
DATE AS OF CHANGE:		20170214

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMICUS THERAPEUTICS INC
		CENTRAL INDEX KEY:			0001178879
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				200422823
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-83043
		FILM NUMBER:		17606169

	BUSINESS ADDRESS:	
		STREET 1:		1 CEDAR BROOK DRIVE
		CITY:			CRANBURY
		STATE:			NJ
		ZIP:			08512
		BUSINESS PHONE:		(609) 662-2000

	MAIL ADDRESS:	
		STREET 1:		1 CEDAR BROOK DRIVE
		CITY:			CRANBURY
		STATE:			NJ
		ZIP:			08512

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Redmile Group, LLC
		CENTRAL INDEX KEY:			0001425738
		IRS NUMBER:				208592298
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		ONE LETTERMAN DRIVE
		STREET 2:		BUILDING D, SUITE D3-300
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129
		BUSINESS PHONE:		415-489-9980

	MAIL ADDRESS:	
		STREET 1:		ONE LETTERMAN DRIVE
		STREET 2:		BUILDING D, SUITE D3-300
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94129
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>d7412614_13g-a.htm
<TEXT>
<html>
<head>
<title></title>
<!--Licensed to: Seward & Kissel
    Document created using EDGARfilings PROfile 4.2.1.0
    Copyright 1995 - 2017 Summit Financial Printing, LLC.  All rights reserved.-->
</head>
<body style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif" bgcolor="#ffffff" text="#000000">
<div><br>
<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-WEIGHT: bold; TEXT-ALIGN: center; MARGIN-TOP: 18pt">UNITED STATES</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-WEIGHT: bold; TEXT-ALIGN: center">SECURITIES AND EXCHANGE COMMISSION</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-WEIGHT: bold; TEXT-ALIGN: center">WASHINGTON, DC 20549</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; FONT-WEIGHT: bold; TEXT-ALIGN: center">SCHEDULE 13G</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">Under the Securities Exchange Act of 1934</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(Amendment No. 4)*</div>

<div><br>
</div>

<div><br>
</div>

<table id="ze86fbd83ae87400c99e6fb7384f3df07" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">Amicus Therapeutics, Inc.</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(Name of Issuer)</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<table id="zb00df0b18e104eeebd9546dab4852f13" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">Common Stock, $0.01 par value per share</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(Title of Class of Securities)</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<table id="za3007a9a32c846baa85d4325a2de505b" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">03152W109</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(CUSIP Number)</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<table id="zee30d2da8d4b449583908c033a0db49c" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">December 31, 2016</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(Date of Event Which Requires Filing of this Statement)</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; TEXT-INDENT: 36pt">Check the appropriate box to designate the rule pursuant to which this Schedule is filed:</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; MARGIN-LEFT: 72pt">[X]&#160; Rule 13d-1(b)</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; MARGIN-LEFT: 72pt">[_]&#160; Rule 13d-1(c)</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; MARGIN-LEFT: 72pt">[_]&#160; Rule 13d-1(d)</div>

<div><br>
</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; TEXT-INDENT: 36pt">The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<table id="z2830bc7cb2b44823872d8fcf0c346fb0" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 13.46%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CUSIP No.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 19.52%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">03152W109</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.42%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="z723150bbcaae4533a3bd4d991a1b5793" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">1.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">NAME OF REPORTING PERSONS</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">2.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 91.86%" colspan="2">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(a)&#160; [_]</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(b)&#160; [X]</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">3.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SEC USE ONLY</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">4.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CITIZENSHIP OR PLACE OF ORGANIZATION</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Delaware</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%" colspan="3">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">5.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SOLE VOTING POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">0</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">6.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SHARED VOTING POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">14,391,130</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">7.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SOLE DISPOSITIVE POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">0</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">8.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SHARED DISPOSITIVE POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">14,391,130</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">9.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 91.86%" colspan="2">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">14,391,130</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">10.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">[_]</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">11.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">9.97%</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">12.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">IA, OO</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>
</table>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<table id="zbffc634096e3433abdbacb995f971c74" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 13.46%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CUSIP No.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 19.52%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">03152W109</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.42%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="zc9ada90f92614943a8ce3cf4b75b37d7" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">1.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">NAME OF REPORTING PERSONS</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">2.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 91.86%" colspan="2">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(a)&#160; [_]</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(b)&#160; [X]</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">3.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SEC USE ONLY</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">4.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CITIZENSHIP OR PLACE OF ORGANIZATION</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">United States</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%" colspan="3">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">5.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SOLE VOTING POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">0</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">6.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SHARED VOTING POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">14,391,130</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">7.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SOLE DISPOSITIVE POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">0</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">8.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SHARED DISPOSITIVE POWER</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">14,391,130</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">9.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 91.86%" colspan="2">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">14,391,130</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">10.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">[_]</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">11.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">9.97%</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">12.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 8.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 81.26%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">IN, HC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.6%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<div><br>
</div>

<table id="zc2d8b7fb38bc449a89908d004e291d18" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 14.17%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">CUSIP No.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 16.14%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">03152W109</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 59.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.62%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="z63c3f64fac8444e8ab8d99d4dabc2b86" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.12%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 1.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.12%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(a)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 72.54%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Name of Issuer:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 72.54%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 72.54%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Amicus Therapeutics, Inc.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="z9dc6eff1a9ad44d0b4c75bbc0536cb3a" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.12%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">(b)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 72.54%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Address of issuer's principal executive offices:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 72.54%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">1 Cedar Brook Drive</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.12%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 72.54%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Cranbury, New Jersey 08512</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="ze0ff0aa8b8cc489faf1b59b0deba50f7" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.1%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 2.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(a)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Name of person filing:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="zcd706dc58121453185c7d604e591e0d3" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(b)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Address or principal business office or, if none, residence:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">One Letterman Drive</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Building D, Suite D3-300</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">The Presidio of San Francisco</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">San Francisco, California&#160; 94129</div>

<div>&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">c/o Redmile Group, LLC</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">One Letterman Drive</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Building D, Suite D3-300</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">The Presidio of San Francisco</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">San Francisco, California&#160; 94129</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="zc0c34c5ae3a24e0fb3371064ff1bdbeb" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(c)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Citizenship:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC &#8211; Delaware</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green &#8211; United States of America</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="zf45652d5275c47569e6e561049ba914a" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(d)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Title of class of securities:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Common Stock, $.01 par value per share</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="z2929b3f7a68d4acabb4df10709eb3500" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(e)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">CUSIP No.:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.1%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 73.02%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">03152W109</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.8%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="zce6a05515cfe431c9820f30e01320685" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.62%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 3.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.38%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">If This Statement is filed pursuant to &#167;&#167;.240.13d-1(b) or 240.13d-2(b), or (c), check whether the person filing is a</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z00884b74e8c2429888a28380a838fcec" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(a)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="ze231051ff5cb4c93958a058ad197ff57" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(b)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="zef4172da521347ada93a9319860c6cc2" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(c)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="ze8f3a18c9bae4dc8be30df05937cf355" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(d)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z0f934181f5ba42119d651d27e8e441d0" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(e)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[X]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">An investment adviser in accordance with <font style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif">&#167;</font>&#160;240.13d-1(b)(1)(ii)(E);</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z3935baa12e334e30ba1b56250415f7a3" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(f)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">An employee benefit plan or endowment fund in accordance with <font style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif">&#167;</font>&#160;240.13d-1(b)(1)(ii)(F);</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z14d2089373c1408cb7f676468f29e718" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(g)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[X]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">A parent holding company or control person in accordance with &#167;240.13d-1(b)(1)(ii)(G);</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="zf5e12f4e527c4a3284402bfe2e40021e" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(h)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C.1813);</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z4e2dde3321554cfa9657dbd632cc4913" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(i)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z05fcca34261640c081799688c0c977a5" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(j)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">A non-U.S. institution in accordance with &#167;240.13d-1(b)(1)(ii)(J);</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="zc88b2fca4cfb4bfdb690d3f9257e2017" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.31%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.24%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(k)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 6.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">[_]</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 80.4%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Group, in accordance with &#167;240.13d-1(b)(1)(ii)(K).&#160; If filing as a non-U.S. institution in accordance with &#167;240.13d-1(b)(1)(ii)(J), please specify the type of institution:</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z15bf3b46f9b3464ba93c2ec36ce067af" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 7.08%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 92.92%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<div><br>
</div>

<table id="zf41fbfd9f6e7473cb7db1801badf4b6a" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 4.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Ownership.<sup style="vertical-align: text-top; line-height: 1; font-size: smaller">1</sup></div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z2cdbbf494967424992c70b82afe54433" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 90.86%" colspan="3">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(a)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Amount beneficially owned:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">14,391,130 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">14,391,130 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(b)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Percent of class:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">9.97%</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">9.97%</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(c)</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Number of shares as to which such person has:</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(i) Sole power to vote or to direct the vote</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">0 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">0 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(ii) Shared power to vote or to direct the vote</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">14,391,130 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">14,391,130 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(iii) Sole power to dispose or to direct the disposition of</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">0 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">0 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">(iv) Shared power to dispose or to direct the disposition of</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Redmile Group, LLC</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">14,391,130 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 56.41%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 25.27%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">14,391,130 shares</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.14%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 9.18%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 56.41%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 25.27%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<br>
<br>
<hr style="BORDER-TOP: 0px; HEIGHT: 1px; BORDER-RIGHT: 0px; BORDER-BOTTOM: 0px; COLOR: #000000; TEXT-ALIGN: left; MARGIN-LEFT: 0pt; BORDER-LEFT: 0px; WIDTH: 2in; BACKGROUND-COLOR: #000000; MARGIN-RIGHT: auto" align="left" noshade="noshade">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left"><sup style="vertical-align: text-top; line-height: 1; font-size: smaller">1</sup> Represented in part by 2,060,000 Warrants to purchase common stock, which may be exchanged for ordinary shares, par value $0.01 per share, at a 1:1 ratio.</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<table id="z6eb45f46a25242cd9b231888ac55ae07" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 5.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Ownership of Five Percent or Less of a Class.</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="zcc49ac5a79a64e77b6d79504527eabb8" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following&#160; [_].</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="zfa14e572cdab41dfae5e6bda05f4a992" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Instruction:&#160; Dissolution of a group requires a response to this item.</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 89.94%">
<div>&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">N/A</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z3629f96b4d2c4146ad966e7c4cf4be51" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; PADDING-BOTTOM: 2px; WIDTH: 10.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 6.</div>
</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Ownership of More Than Five Percent on Behalf of Another Person.</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">N/A</div>
</td>
</tr>
</table>

<div>&#160;</div>

<table id="z2f58ae19e56641779c8c9773ffc12d84" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 7.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="ze868f7a11138407c945dc75f89963942" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.78%" colspan="2">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">If a parent holding company or control person has filed this schedule, pursuant to Rule 13d-1(b)(1)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary.&#160; If a parent holding company or control person has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.</div>

<div>&#160;</div>
</td>
</tr>

<tr style="HEIGHT: 19px">
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 41.78%" colspan="2">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">See Exhibit B attached hereto.</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.22%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 41.78%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 47.34%">&#160;</td>
</tr>
</table>

<div><br>
</div>

<table id="z752595e03a0e47c79ce906007a55ffc1" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 8.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Identification and Classification of Members of the Group.</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z4c24247dbc464cd8a2c6b94d2149131b" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">N/A</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="za3d6dc6c345a48549fe6aa38660dcf83" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 9.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Notice of Dissolution of Group.</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="za9b13f93f19a48a6868743e1c53f3967" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.06%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.94%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">N/A</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="zfa1247b70ae24c0691fc7b2e3d91199e" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 10.28%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Item 10.</div>
</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 89.72%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Certification.</div>
</td>
</tr>
</table>

<div><br>
</div>

<table id="z20dfd94dd9554db8a31f2070f52129ae" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 100%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; TEXT-INDENT: 36pt">By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">SIGNATURE</div>

<div><br>
</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left; TEXT-INDENT: 36pt">After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.</div>

<div><br>
</div>

<table id="z2f149f5e7ff544149d6a43618fb9f51d" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">February 14, 2017</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(Date)</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">REDMILE GROUP, LLC</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">/s/ Jeremy C. Green</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green, Managing Member</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 50%">
<div>&#160;</div>

<div>&#160;</div>

<div>&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">JEREMY C. GREEN</div>

<div>&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">&#160;/s/ Jeremy C. Green</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">The original statement shall be signed by each person on whose behalf the statement is filed or his authorized representative.&#160; If the statement is signed on behalf of a person by his authorized representative other than an executive officer or general partner of the filing person, evidence of the representative's authority to sign on behalf of such person shall be filed with the statement, provided, however, that a power of attorney for this purpose which is already on file with the Commission may be incorporated by reference.&#160; The name and any title of each person who signs the statement shall be typed or printed beneath his signature.</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Note.&#160; Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See s.240.13d-7 for other parties for whom copies are to be sent.</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Attention.&#160; Intentional misstatements or omissions of fact constitute Federal criminal violations (see 18 U.S.C. 1001).</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">Exhibit A</div>

<div><br>
</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">AGREEMENT</div>

<div><br>
</div>

<div><br>
</div>

<div style="MARGIN-BOTTOM: 12pt; FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">The undersigned agree that this Schedule 13G, Amendment 4, dated February 14, 2017, relating to the common stock, par value $0.01, of Amicus Therapeutics, Inc. shall be filed on behalf of the undersigned.</div>

<div style="MARGIN-BOTTOM: 12pt"><br>
</div>

<table id="z3caa4e1fa33f4cc7bbd68b10ca64d46b" style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; BORDER-COLLAPSE: collapse; WIDTH: 100%" cellspacing="0" cellpadding="0">
<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">&#160;February 14, 2017</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: center">(Date)</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">REDMILE GROUP, LLC</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: #000000 2px solid; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">/s/ Jeremy C. Green</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="BORDER-TOP: #000000 2px solid; VERTICAL-ALIGN: top; WIDTH: 50%">
<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">Jeremy C. Green, Managing Member</div>
</td>
</tr>

<tr>
<td style="VERTICAL-ALIGN: top; WIDTH: 50%">&#160;</td>
<td style="VERTICAL-ALIGN: top; BORDER-BOTTOM: black 2px solid; WIDTH: 50%">
<div>&#160;</div>

<div>&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">JEREMY C. GREEN</div>

<div>&#160;</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">&#160;/s/ Jeremy C. Green</div>
</td>
</tr>
</table>

<div><br>
</div>

<div><br>
</div>

<div id="DSPFPageBreakArea" style="MARGIN-BOTTOM: 10pt; CLEAR: both; MARGIN-TOP: 10pt">
<div id="DSPFPageBreak" style="PAGE-BREAK-AFTER: always">
<hr style="BORDER-LEFT-WIDTH: 0px; HEIGHT: 2px; BORDER-RIGHT-WIDTH: 0px; BORDER-BOTTOM-WIDTH: 0px; COLOR: #000000; CLEAR: both; MARGIN: 4px 0px; BORDER-TOP-WIDTH: 0px; WIDTH: 100%; BACKGROUND-COLOR: #000000" noshade="noshade">
</div>
</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: right">Exhibit B</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: justify">Redmile Group, LLC is the relevant entity for which Jeremy C. Green may be considered a control person.</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div><br>
</div>

<div style="FONT-SIZE: 10pt; FONT-FAMILY: 'Times New Roman', Times, serif; TEXT-ALIGN: left">SK 25839 0001 7412614</div>
</div>
</body>
</html>

</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
