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v3.8.0.1

Leases (Details) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2017 USD ($) ft² | Dec. 31, 2016 USD ($) | Dec. 31, 2015 USD ($)
Minimum lease payments |  |  |
2018 | $ 2,762 |  |
2019 | 2,575 |  |
2020 | 2,472 |  |
2021 | 2,240 |  |
2022 and beyond | 8,467 |  |
Total | 18,516 |  |
Rent expense, including fees for utilities and common area maintenances | 3,900 | $ 3,500 | $ 2,600
Equipment |  |  |
Capital Leases |  |  |
Capital lease obligation |  | $ 900 |
2018 | 356 |  |
2019 | 134 |  |
Total principal obligation | $ 490 |  |
Equipment | Minimum |  |  |
Capital Leases |  |  |
Fixed interest rate (as a percent) |  | 0.20% |
Term of capital lease (in months) |  | 36 months |
Equipment | Maximum |  |  |
Capital Leases |  |  |
Fixed interest rate (as a percent) |  | 5.70% |
Term of capital lease (in months) |  | 48 months |
Cranbury, New Jersey | Office and laboratory space |  |  |
Operating Leases |  |  |
Area of space leased (in square feet) | ft² | 90,000 |  |
Durham, North Carolina | Office space |  |  |
Operating Leases |  |  |
Area of space leased (in square feet) | ft² | 5,603 |  |
Buckinghamshire, United Kingdom | Office space |  |  |
Operating Leases |  |  |
Area of space leased (in square feet) | ft² | 9,821 |  |
Munich, Germany | Office space |  |  |
Operating Leases |  |  |
Area of space leased (in square feet) | ft² | 4,751 |  |

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- Definition Represents the amount of required minimum rental payments maturing in the fifth fiscal year following the latest fiscal year and thereafter for operating leases having an initial or remaining noncancelable letter-term in excess of one year. + References No definition available. + Details
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- Definition Amount equal to the present value (the principal) at the beginning of the lease term of minimum lease payments during the lease term (excluding that portion of the payments representing executory costs such as insurance, maintenance, and taxes to be paid by the lessor, together with any profit thereon) net of payments or other amounts applied to the principal through the balance sheet date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 840 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=84164817&loc=d3e45280-112737 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(22)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 944 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.7-03(a)(16)) -URI http://asc.fasb.org/extlink&oid=6879938&loc=d3e572229-122910 + Details
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