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Summary of Significant Accounting Policies - Equity Incentive Plan and Stock-Based Compensation (Details)	Dec. 31, 2017 item
Equity-based Compensation
Number of equity-based employee compensation plans	3

X

- Definition

Represents the number of plans under the equity-based arrangements.

+ References

No definition available.

+ Details

Name:	fold_ShareBasedCompensationNumberOfPlans
Namespace Prefix:	fold_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	instant

X

- References

No definition available.

+ Details

Name:	us-gaap_ShareBasedCompensationAbstract
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration