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Summary of Significant Accounting Policies - Foreign Currency Transactions (Details) - USD ($) $ in Thousands | 9 Months Ended |
--- | --- | ---
Sep. 30, 2018 | Sep. 30, 2017 | Dec. 31, 2017
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |
Total stockholders’ equity | $ 410,951 |  | $ 352,850
Retained earnings (accumulated deficit) | (1,334,141) |  | $ (1,063,610)
Net cash used in operating activities | (239,278) | $ (140,661) |
Accounting Standards Update 2018-02 |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |
Retained earnings (accumulated deficit) | 383 |  |
Accounting Standards Update 2016-18 |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |
Net cash used in operating activities |  | $ 1,100 |
Accumulated Foreign Currency Adjustment Attributable | Accounting Standards Update 2018-02 |  |  |
New Accounting Pronouncements or Change in Accounting Principle [Line Items] |  |  |
Total stockholders’ equity | $ (383) |  |

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