Share based Compensation - Narrative (Details) $ / shares in Units, $ in Millions	9 Months Ended
Sep. 30, 2018 USD ($) $ / shares shares
Options to purchase common stock
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total unrecognized compensation costs \| $	$ 36.0
Unrecognized compensation costs, period for recognition (in years)	3 years
MPRSUs, Exercisable at period end (in shares)	9,406,000
Market Performance Based Restricted Stock Units \| Stock Option Plan Amended Restated 2007 Equity Incentive Plan \| Executive Officer
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Market performance-based restricted stock units granted (in shares)	187,222
Award vesting period (in years)	3 years
MPRSUs granted, weighted average exercise price (in dollars per share) \| $ / shares	$ 25.44
Market Performance Based Restricted Stock Units \| Stock Option Plan Amended Restated 2007 Equity Incentive Plan \| Executive Officer \| Maximum
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Award vesting rights	200.00%
MPRSUs, Exercisable at period end (in shares)	374,444
Market Performance Based Restricted Stock Units \| Stock Option Plan Amended Restated 2007 Equity Incentive Plan \| Executive Officer \| Cliff Vesting
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Award vesting period (in years)	3 years
Unvested restricted stock units \| Stock Option Plan Amended Restated 2007 Equity Incentive Plan
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Unrecognized compensation costs, period for recognition (in years)	3 years
Market performance-based restricted stock units granted (in shares)	1,635,000
MPRSUs granted, weighted average exercise price (in dollars per share) \| $ / shares	$ 16.57
RSUs vested and non-vested units expected to vest (in shares)	516,940
Unrecognized compensation cost \| $	$ 25.6
Unvested restricted stock units \| Stock Option Plan Amended Restated 2007 Equity Incentive Plan \| Contingent Consideration Liability Clinical Milestone
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Market performance-based restricted stock units granted (in shares)	187,211
Award vesting period (in years)	3 years

Weighted average period over which unrecognized compensation is expected to be recognized for equity-based compensation plans, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Unrecognized cost of unvested share-based awards, other than options, awarded to employees as compensation.

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Unrecognized cost of unvested options awarded to employees as compensation.

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Period which an employee's right to exercise an award is no longer contingent on satisfaction of either a service condition, market condition or a performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The number of equity-based payment instruments, excluding stock (or unit) options, that vested during the reporting period.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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Percentage of vesting of share-based compensation awards.

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