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Consolidated Balance Sheets - USD ($) $ in Thousands | Dec. 31, 2018 | Dec. 31, 2017
--- | --- | ---
Current assets: |  |
Cash and cash equivalents | $ 79,749 | $ 49,060
Investments in marketable securities | 424,403 | 309,502
Accounts receivable | 21,962 | 9,464
Inventories | 8,390 | 4,623
Prepaid expenses and other current assets | 16,592 | 19,316
Total current assets | 551,096 | 391,965
Property and equipment, less accumulated depreciation of $15,671 and $12,515 at December 31, 2018 and 2017, respectively | 11,375 | 9,062
In-process research & development | 23,000 | 23,000
Goodwill | 197,797 | 197,797
Other non-current assets | 6,683 | 5,200
Total Assets | 789,951 | 627,024
Current liabilities: |  |
Accounts payable, accrued expenses, and other current liabilities | 80,625 | 53,890
Deferred reimbursements | 5,500 | 7,750
Contingent consideration payable | 0 | 8,400
Total current liabilities | 86,125 | 70,040
Deferred reimbursements | 10,156 | 14,156
Convertible notes | 175,006 | 164,167
Senior secured term loan | 146,734 | 0
Contingent consideration payable | 19,700 | 17,000
Deferred income taxes | 6,465 | 6,465
Other non-current liabilities | 2,853 | 2,346
Total Liabilities | 447,039 | 274,174
Commitments and contingencies |  |
Stockholders' equity: |  |
Common stock, $.01 par value, 500,000,000 shares authorized, 189,383,924 shares issued and outstanding at December 31, 2018 Common stock, $.01 par value, 250,000,000 shares authorized, 166,989,790 shares issued and outstanding at December 31, 2017 | 1,942 | 1,721
Additional paid-in capital | 1,740,061 | 1,400,758
Accumulated other comprehensive loss: |  |
Foreign currency translation adjustment | 495 | (1,659)
Unrealized loss on available-for securities | (427) | (436)
Warrants | 13,063 | 16,076
Accumulated deficit | (1,412,222) | (1,063,610)
Total stockholders' equity | 342,912 | 352,850
Total Liabilities and Stockholders' Equity | $ 789,951 | $ 627,024

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