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Accounts Payable and Accrued Expenses | 12 Months Ended
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Dec. 31, 2018
Payables and Accruals [Abstract] |
Accounts Payable and Accrued Expenses | Accounts Payable and Accrued Expenses Accounts payable and accrued expenses consist of the following:
| December 31,
(in thousands) | 2018 |  | 2017
Accounts payable | $ | 6,606 |  |  | $ | 7,867 |
Accrued professional fees | 2,276 |  |  | 5,845 |
Accrued contract manufacturing & contract research costs | 5,890 |  |  | 4,632 |
Accrued compensation and benefits | 21,731 |  |  | 19,620 |
Accrued facility costs | 2,102 |  |  | 1,665 |
Accrued program fees | 16,674 |  |  | 5,707 |
Royalties payable | 4,463 |  |  | 2,529 |
Accrued interest | 4,189 |  |  | 313 |
Milestone payments | 9,000 |  |  | — |
Accrued sales rebates and discounts | 3,636 |  |  | 1,957 |
Other | 4,058 |  |  | 3,755 |
| $ | 80,625 |  |  | $ | 53,890 |

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- Definition The entire disclosure for accounts payable and accrued liabilities at the end of the reporting period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.19(a),20,24) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- References No definition available. + Details
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