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Licenses (Details) - USD ($)	12 Months Ended
	Dec. 31, 2018	Sep. 30, 2018
License agreement | MSSM
Licenses
Upfront and annual license fees paid	$ 0
Potential milestone payments	0
Royalty expense	$ 7,600,000
Celenex
Licenses
Contingent consideration based on the achievement of certain milestones		$ 15,000,000
Nationwide Children's Hospital | Celenex
Licenses
Contingent consideration based on the achievement of certain milestones		$ 7,800,000

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 220
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.3)
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